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The map label for this gene is cvrA [H]

Identifier: 29346095

GI number: 29346095

Start: 851405

End: 852877

Strand: Reverse

Name: cvrA [H]

Synonym: BT_0685

Alternate gene names: 29346095

Gene position: 852877-851405 (Counterclockwise)

Preceding gene: 161511194

Following gene: 29346094

Centisome position: 13.62

GC content: 46.84

Gene sequence:

>1473_bases
ATGATATTTACAGCAGAAAACACCCTACTAATTGGTTCTATCTTACTTTTCGTTAGCATCGTTGTCGGAAAAACAGGATA
TCGCTTCGGAGTGCCCACCTTATTACTGTTCCTCGTAGTAGGAATGTTGTTCGGAAGTGACGGACTCGGACTCCAGTTTC
ATGACGCAAAAGATGCGCAATTCATCGGTATGGTTGCTTTAAGCATCATCCTGTTTTCGGGAGGTATGGATACGAAATTC
AGAGAAATCAAACCCATTTTAGGTCCAGGTATCGTGCTTTCTACCGTCGGAGTTCTACTAACCGCTCTTTTCACCGGATT
ATTTATCTGGTGGCTGTCCGGAATGAGCTGGACGAATATCTATCTGCCTATCACCACGTCATTGCTACTGGCATCTACCA
TGTCCTCTACGGACTCGGCTTCGGTGTTCGCCATCCTGCGTTCGCAGAAGATGAATCTGAAACACAACCTCCGCCCCATG
CTGGAGCTGGAAAGTGGAAGTAACGACCCGATGGCATACATGCTCACCATTGTCCTGATACAGTTTATCCAATCGGCAGG
TATGGGAGTCGGGGCTATCGCCGCTTCTTTCATCATTCAGTTTATAGTCGGCGCGGCTGCCGGATACGTGCTCGGAAAAC
TGGCTATCCGTATGCTGAACAAGCTCAACATCGACAATCAGGCGTTGTATCCTATCTTGTTGCTGGCGTTTGTTTTCTTC
ACCTTCTCTATCACTGATTTACTGAAAGGAAATGGTTACCTTGCCGTATATATCGCAGGTATTATGGTAGGAAACAACAA
GATCATGCACCGCAAAGACATTTATACGTTCATGGACGGACTTACCTGGTTGTTCCAGATCATCATGTTCCTCTGCCTCG
GACTTCTCGTTAATCCTCATGAAATGCTGGAAGTTGCAGCAGTAGCACTATTGATCGGTGTCTTCATGATTGTGATCGGT
CGCCCGTTAAGTGTGTTCCTCTGTTTGCTTCCGTTCCGGAAGATTACAATGAAATCGCGGCTGTTCGTCTCCTGGGTAGG
ATTGCGTGGAGCAGTTCCCATTATCTTCGCCACTTATCCGGTGGTTGCAGGAGTCGAAGGATCGAATATTATCTTTAATG
TCGTATTCTTCATCACAATCGTTTCACTGGTAGTGCAGGGAACAACGGTTTCTTTCGTTGCCCGCCTGTTACATCTGTCC
AAACCGCTGGAAAAGACGGGGAATGATTTCGGAGTGGAACTTCCGGAAGAGATTGATACAGACCTCAAAGATATGACTAT
CACACAGGAAATGCTGGAAGAGGCAGATACGCTGAAAGATATGAATCTCCCCAAAGGCACGCTGGTAATGATTGTGAAAC
GTGGGGATGAGTTCCTGATACCGAACGGAACGCTGAAACTGCATGTGAACGATAAATTGCTGCTCATCTCCGAAAAGCCC
AAAGAGGACGAGGAAGCCAACAGCGAATCCTGA

Upstream 100 bases:

>100_bases
AAATACATCCAAAAAGACTCTTTATTTGTTTTAAATAATGTGTAACTTCGCACGGTGAGACCTATTACGACACATTTAAT
AACTTAATAATATATTGCCT

Downstream 100 bases:

>100_bases
TGTTTATAGGGACTGACTAAAAAGTCAATAGTATCTCCAATTCCCCTCCTTTCGGAAAGGAGAGGTGGCTGAAAGCCGGG
GTGGTAGGTAAAATAAGGTT

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MIFTAENTLLIGSILLFVSIVVGKTGYRFGVPTLLLFLVVGMLFGSDGLGLQFHDAKDAQFIGMVALSIILFSGGMDTKF
REIKPILGPGIVLSTVGVLLTALFTGLFIWWLSGMSWTNIYLPITTSLLLASTMSSTDSASVFAILRSQKMNLKHNLRPM
LELESGSNDPMAYMLTIVLIQFIQSAGMGVGAIAASFIIQFIVGAAAGYVLGKLAIRMLNKLNIDNQALYPILLLAFVFF
TFSITDLLKGNGYLAVYIAGIMVGNNKIMHRKDIYTFMDGLTWLFQIIMFLCLGLLVNPHEMLEVAAVALLIGVFMIVIG
RPLSVFLCLLPFRKITMKSRLFVSWVGLRGAVPIIFATYPVVAGVEGSNIIFNVVFFITIVSLVVQGTTVSFVARLLHLS
KPLEKTGNDFGVELPEEIDTDLKDMTITQEMLEEADTLKDMNLPKGTLVMIVKRGDEFLIPNGTLKLHVNDKLLLISEKP
KEDEEANSES

Sequences:

>Translated_490_residues
MIFTAENTLLIGSILLFVSIVVGKTGYRFGVPTLLLFLVVGMLFGSDGLGLQFHDAKDAQFIGMVALSIILFSGGMDTKF
REIKPILGPGIVLSTVGVLLTALFTGLFIWWLSGMSWTNIYLPITTSLLLASTMSSTDSASVFAILRSQKMNLKHNLRPM
LELESGSNDPMAYMLTIVLIQFIQSAGMGVGAIAASFIIQFIVGAAAGYVLGKLAIRMLNKLNIDNQALYPILLLAFVFF
TFSITDLLKGNGYLAVYIAGIMVGNNKIMHRKDIYTFMDGLTWLFQIIMFLCLGLLVNPHEMLEVAAVALLIGVFMIVIG
RPLSVFLCLLPFRKITMKSRLFVSWVGLRGAVPIIFATYPVVAGVEGSNIIFNVVFFITIVSLVVQGTTVSFVARLLHLS
KPLEKTGNDFGVELPEEIDTDLKDMTITQEMLEEADTLKDMNLPKGTLVMIVKRGDEFLIPNGTLKLHVNDKLLLISEKP
KEDEEANSES
>Mature_490_residues
MIFTAENTLLIGSILLFVSIVVGKTGYRFGVPTLLLFLVVGMLFGSDGLGLQFHDAKDAQFIGMVALSIILFSGGMDTKF
REIKPILGPGIVLSTVGVLLTALFTGLFIWWLSGMSWTNIYLPITTSLLLASTMSSTDSASVFAILRSQKMNLKHNLRPM
LELESGSNDPMAYMLTIVLIQFIQSAGMGVGAIAASFIIQFIVGAAAGYVLGKLAIRMLNKLNIDNQALYPILLLAFVFF
TFSITDLLKGNGYLAVYIAGIMVGNNKIMHRKDIYTFMDGLTWLFQIIMFLCLGLLVNPHEMLEVAAVALLIGVFMIVIG
RPLSVFLCLLPFRKITMKSRLFVSWVGLRGAVPIIFATYPVVAGVEGSNIIFNVVFFITIVSLVVQGTTVSFVARLLHLS
KPLEKTGNDFGVELPEEIDTDLKDMTITQEMLEEADTLKDMNLPKGTLVMIVKRGDEFLIPNGTLKLHVNDKLLLISEKP
KEDEEANSES

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=480, Percent_Identity=39.375, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 53774; Mature: 53774

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFTAENTLLIGSILLFVSIVVGKTGYRFGVPTLLLFLVVGMLFGSDGLGLQFHDAKDAQ
CEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHH
FIGMVALSIILFSGGMDTKFREIKPILGPGIVLSTVGVLLTALFTGLFIWWLSGMSWTNI
HHHHHHHHHHHHCCCCCCHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
YLPITTSLLLASTMSSTDSASVFAILRSQKMNLKHNLRPMLELESGSNDPMAYMLTIVLI
EEHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCEEEECCCCCCHHHHHHHHHHH
QFIQSAGMGVGAIAASFIIQFIVGAAAGYVLGKLAIRMLNKLNIDNQALYPILLLAFVFF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TFSITDLLKGNGYLAVYIAGIMVGNNKIMHRKDIYTFMDGLTWLFQIIMFLCLGLLVNPH
HHHHHHHHCCCCEEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EMLEVAAVALLIGVFMIVIGRPLSVFLCLLPFRKITMKSRLFVSWVGLRGAVPIIFATYP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHH
VVAGVEGSNIIFNVVFFITIVSLVVQGTTVSFVARLLHLSKPLEKTGNDFGVELPEEIDT
HHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHCC
DLKDMTITQEMLEEADTLKDMNLPKGTLVMIVKRGDEFLIPNGTLKLHVNDKLLLISEKP
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCEEEEEECCEEEEEECCC
KEDEEANSES
CCCCCCCCCC
>Mature Secondary Structure
MIFTAENTLLIGSILLFVSIVVGKTGYRFGVPTLLLFLVVGMLFGSDGLGLQFHDAKDAQ
CEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHH
FIGMVALSIILFSGGMDTKFREIKPILGPGIVLSTVGVLLTALFTGLFIWWLSGMSWTNI
HHHHHHHHHHHHCCCCCCHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
YLPITTSLLLASTMSSTDSASVFAILRSQKMNLKHNLRPMLELESGSNDPMAYMLTIVLI
EEHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCEEEECCCCCCHHHHHHHHHHH
QFIQSAGMGVGAIAASFIIQFIVGAAAGYVLGKLAIRMLNKLNIDNQALYPILLLAFVFF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TFSITDLLKGNGYLAVYIAGIMVGNNKIMHRKDIYTFMDGLTWLFQIIMFLCLGLLVNPH
HHHHHHHHCCCCEEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EMLEVAAVALLIGVFMIVIGRPLSVFLCLLPFRKITMKSRLFVSWVGLRGAVPIIFATYP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHH
VVAGVEGSNIIFNVVFFITIVSLVVQGTTVSFVARLLHLSKPLEKTGNDFGVELPEEIDT
HHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHCC
DLKDMTITQEMLEEADTLKDMNLPKGTLVMIVKRGDEFLIPNGTLKLHVNDKLLLISEKP
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCEEEEEECCEEEEEECCC
KEDEEANSES
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA