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The map label for this gene is xpt

Identifier: 29345837

GI number: 29345837

Start: 513881

End: 514453

Strand: Reverse

Name: xpt

Synonym: BT_0427

Alternate gene names: 29345837

Gene position: 514453-513881 (Counterclockwise)

Preceding gene: 29345838

Following gene: 29345818

Centisome position: 8.22

GC content: 41.88

Gene sequence:

>573_bases
ATGCAATTACTAAAAAAAAGAATTCTGCAGGACGGAAAATGCTACGAAGGAGGCATCCTTAAAGTAGATGGTTTTATCAA
TCACCAGATGGATCCTGTCCTGATGAAATCCATCGGAGTAGAATTTGTCCGCCGCTTTGCAGCCACAAACGTAAACAAGA
TCATGACTATAGAAGCAAGCGGTATCGCTCCTGCCATCATGACGGGCTATCTCATGGACTTACCGGTTGTATTCGCCAAA
AAGAAATCACCCAAAACCATTCAGAACGCACTAAGCACTACCGTACACTCGTTCACCAAAGACCGTGATTATGAAGTAGT
GATCAGTGCCGATTTTCTGACTCCAAATGACAATGTTCTTTTTGTTGATGATTTCCTTGCCTACGGAAATGCCGCATTAG
GCATTCTCGACCTCATAGAGCAATCCGGAGCAAAATTGGTAGGCATGGGGTTCATTATCGAAAAAGCCTTCCAAAATGGA
CGTAAAATACTGGAAGAGAAAGGTGTCAGAGTAGAAAGCCTTGCCATAATCGAAGACTTATCCAACTGCTGTATTAAAAT
AAAAGATCAATAA

Upstream 100 bases:

>100_bases
ATAAATATTCAAATGCCCGATGTGCTAATATGCCAACCCAATACTGTATGATATCAGTAACAAATGGCATATTAGCACAT
TATTTAATTATCAGATTATA

Downstream 100 bases:

>100_bases
GCTGAGTCGGGGTTAAAATAATGCCCCTTGCCTTTTGTCTTTTTACCATATTGCACCGCATGCTGAGGGCACACATGATA
ACATGCCAGGCAGGCGGTGC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MQLLKKRILQDGKCYEGGILKVDGFINHQMDPVLMKSIGVEFVRRFAATNVNKIMTIEASGIAPAIMTGYLMDLPVVFAK
KKSPKTIQNALSTTVHSFTKDRDYEVVISADFLTPNDNVLFVDDFLAYGNAALGILDLIEQSGAKLVGMGFIIEKAFQNG
RKILEEKGVRVESLAIIEDLSNCCIKIKDQ

Sequences:

>Translated_190_residues
MQLLKKRILQDGKCYEGGILKVDGFINHQMDPVLMKSIGVEFVRRFAATNVNKIMTIEASGIAPAIMTGYLMDLPVVFAK
KKSPKTIQNALSTTVHSFTKDRDYEVVISADFLTPNDNVLFVDDFLAYGNAALGILDLIEQSGAKLVGMGFIIEKAFQNG
RKILEEKGVRVESLAIIEDLSNCCIKIKDQ
>Mature_190_residues
MQLLKKRILQDGKCYEGGILKVDGFINHQMDPVLMKSIGVEFVRRFAATNVNKIMTIEASGIAPAIMTGYLMDLPVVFAK
KKSPKTIQNALSTTVHSFTKDRDYEVVISADFLTPNDNVLFVDDFLAYGNAALGILDLIEQSGAKLVGMGFIIEKAFQNG
RKILEEKGVRVESLAIIEDLSNCCIKIKDQ

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_BACTN (Q8AAN7)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809340.1
- HSSP:   P42085
- ProteinModelPortal:   Q8AAN7
- SMR:   Q8AAN7
- GeneID:   1072656
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0427
- NMPDR:   fig|226186.1.peg.427
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   BTHE226186:BT_0427-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21018; Mature: 21018

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLKKRILQDGKCYEGGILKVDGFINHQMDPVLMKSIGVEFVRRFAATNVNKIMTIEAS
CHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GIAPAIMTGYLMDLPVVFAKKKSPKTIQNALSTTVHSFTKDRDYEVVISADFLTPNDNVL
CCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEE
FVDDFLAYGNAALGILDLIEQSGAKLVGMGFIIEKAFQNGRKILEEKGVRVESLAIIEDL
EEEHHHHHCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SNCCIKIKDQ
HHCEEEECCC
>Mature Secondary Structure
MQLLKKRILQDGKCYEGGILKVDGFINHQMDPVLMKSIGVEFVRRFAATNVNKIMTIEAS
CHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GIAPAIMTGYLMDLPVVFAKKKSPKTIQNALSTTVHSFTKDRDYEVVISADFLTPNDNVL
CCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEE
FVDDFLAYGNAALGILDLIEQSGAKLVGMGFIIEKAFQNGRKILEEKGVRVESLAIIEDL
EEEHHHHHCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SNCCIKIKDQ
HHCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928