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The map label for this gene is arsA [H]

Identifier: 29345526

GI number: 29345526

Start: 107019

End: 108731

Strand: Reverse

Name: arsA [H]

Synonym: BT_0116

Alternate gene names: 29345526

Gene position: 108731-107019 (Counterclockwise)

Preceding gene: 29345527

Following gene: 29345525

Centisome position: 1.74

GC content: 40.57

Gene sequence:

>1713_bases
ATGAAAGCATTTAATTTATCCGATATAGAACTAACAAAATACTTATTCTTCACAGGAAAAGGTGGAGTAGGAAAAACCTC
TATTGCTTGCGCTACGGCAGTGGGATTAGCTGATAAAGGGGAGAAAATTCTTCTTATCAGTACAGACCCGGCTTCTAACC
TGCAAGATGTTTTCAATCAAACCCTAAACGGACATGGTACAGCTATTTCAGAAGTACCGGGGCTGACGGTCGTAAACCTT
GACCCTGAACAGGCAGCAGCAGAGTACAGGGAAAGTGTGATTGCACCTTTTAGAGGACAATTACCTGAAAGCGTTATTCA
AAATATGGAAGAACAACTTTCAGGCTCTTGTACGGTAGAAATCGCTGCCTTTAATGAGTTTTCAGACTTTATCACCGATG
CTGATAAAGCGAAGGAATACGACCACATTATTTTTGATACAGCACCTACCGGACACACATTGCGAATGTTGCAGCTTCCA
TCGGCATGGAGTACATTTATTAGTGAAAGTACACATGGCGCATCTTGTTTAGGACAATTATCAGGCTTGGAAGAAAGGAA
AGGTATCTATAAACAGGCGGTTGATACATTGTCTGATACAAGCGCAACCCGGTTAGTATTGGTAAGCCGTCCTGAAATAG
CACCGTTGAAAGAAGCTGCCCGTTCTTCGCATGAATTACAACTATTGGGAATTAAAAATCAGCTATTGGTGATAAATGGT
GTTTTACAGCAATTAGATGAAGCAGACAATGTTTCACAACAACTGTATAACAGGCAGCAAAAGGCGTTACAAAGTATGCC
TATTGCATTATCTGAATATCCCATGTATAGCGTTCCTCTGCGTTCTTACAATTTATCCAATATTGCCAATATCCGCCGTA
TGCTATACAGTGATAGTATTACGAATGAAATTCGTTATCAGCCGATAACTGATAGCAAAAGTATAGATGAATTGGTAAAT
GACCTCTATACTTCCGGTAAACGAGTAGTGTTCACAATGGGAAAAGGTGGCGTAGGAAAAACGACCTTAGCCACAGAAAT
AGCCTTGAAATTAACAAAGCTCGGTGCAAAGGTTCATCTTACCACTACTGACCCGGCAAATCACCTGAACTATGATTTTG
CCATCAAATCAGGTATTACGGTAAGCCATATAGACGAAGCGGAAGTGCTGGAAAAATACAAGAATGAAGTTCGTAGCAAA
GCTGCCGAAACCATGACTGCCGAAGATATGGAATATATAGAGGAAGATTTACGTTCACCATGTACGCAAGAAATCGCCGT
ATTTAAGGCTTTTGCTGAAATTGTAGATAAAGCGGAGAATGAAATCGTAGTGATTGATACTGCACCAACAGGACATACTT
TGTTGCTTTTGGATGCTACCCAAAGCTATCACAAAGAAGTAGAACGTACACAGGGAGAAGTAACCGGAGCAGTAGCCAAT
TTATTACCCCGTTTACGCAATCCACAGGAAACGGAAGTAGTAATAGTCACTTTACCCGAAGCAACACCTGTTTTTGAAGC
AGAACGCCTACAAATGGATTTGCAGCGTGCCGGGATTAACAACAAATGGTGGGTAGTAAATGCCTGTTTGTCATTGACAA
ATACAGCAAATTCATTTTTGCAAGCAAAAGCGCAAAGTGAATTGACTTGGATTAAGAAAGTAGAAGAATTGTCAAAGGGC
AATACTGCCCTGATTGAATGGAAAAACTTATAA

Upstream 100 bases:

>100_bases
TAAAGATTATCCCACAACTAAACAAATGAGTGAATGGACAGGAATTAATTTAGACTTGATGCCCGTTAAATAATCGTTGA
ACAAATTAATATACAGAATA

Downstream 100 bases:

>100_bases
GAATATGAAGATTTTAATCCTTTGCACTGGTAACAGTTGCCGTAGCCAAATGGCACACGGTTTCTTACAGTCATTCGATA
AAAACATGGATGTCTTTTCA

Product: arsenical pump-driving ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MKAFNLSDIELTKYLFFTGKGGVGKTSIACATAVGLADKGEKILLISTDPASNLQDVFNQTLNGHGTAISEVPGLTVVNL
DPEQAAAEYRESVIAPFRGQLPESVIQNMEEQLSGSCTVEIAAFNEFSDFITDADKAKEYDHIIFDTAPTGHTLRMLQLP
SAWSTFISESTHGASCLGQLSGLEERKGIYKQAVDTLSDTSATRLVLVSRPEIAPLKEAARSSHELQLLGIKNQLLVING
VLQQLDEADNVSQQLYNRQQKALQSMPIALSEYPMYSVPLRSYNLSNIANIRRMLYSDSITNEIRYQPITDSKSIDELVN
DLYTSGKRVVFTMGKGGVGKTTLATEIALKLTKLGAKVHLTTTDPANHLNYDFAIKSGITVSHIDEAEVLEKYKNEVRSK
AAETMTAEDMEYIEEDLRSPCTQEIAVFKAFAEIVDKAENEIVVIDTAPTGHTLLLLDATQSYHKEVERTQGEVTGAVAN
LLPRLRNPQETEVVIVTLPEATPVFEAERLQMDLQRAGINNKWWVVNACLSLTNTANSFLQAKAQSELTWIKKVEELSKG
NTALIEWKNL

Sequences:

>Translated_570_residues
MKAFNLSDIELTKYLFFTGKGGVGKTSIACATAVGLADKGEKILLISTDPASNLQDVFNQTLNGHGTAISEVPGLTVVNL
DPEQAAAEYRESVIAPFRGQLPESVIQNMEEQLSGSCTVEIAAFNEFSDFITDADKAKEYDHIIFDTAPTGHTLRMLQLP
SAWSTFISESTHGASCLGQLSGLEERKGIYKQAVDTLSDTSATRLVLVSRPEIAPLKEAARSSHELQLLGIKNQLLVING
VLQQLDEADNVSQQLYNRQQKALQSMPIALSEYPMYSVPLRSYNLSNIANIRRMLYSDSITNEIRYQPITDSKSIDELVN
DLYTSGKRVVFTMGKGGVGKTTLATEIALKLTKLGAKVHLTTTDPANHLNYDFAIKSGITVSHIDEAEVLEKYKNEVRSK
AAETMTAEDMEYIEEDLRSPCTQEIAVFKAFAEIVDKAENEIVVIDTAPTGHTLLLLDATQSYHKEVERTQGEVTGAVAN
LLPRLRNPQETEVVIVTLPEATPVFEAERLQMDLQRAGINNKWWVVNACLSLTNTANSFLQAKAQSELTWIKKVEELSKG
NTALIEWKNL
>Mature_570_residues
MKAFNLSDIELTKYLFFTGKGGVGKTSIACATAVGLADKGEKILLISTDPASNLQDVFNQTLNGHGTAISEVPGLTVVNL
DPEQAAAEYRESVIAPFRGQLPESVIQNMEEQLSGSCTVEIAAFNEFSDFITDADKAKEYDHIIFDTAPTGHTLRMLQLP
SAWSTFISESTHGASCLGQLSGLEERKGIYKQAVDTLSDTSATRLVLVSRPEIAPLKEAARSSHELQLLGIKNQLLVING
VLQQLDEADNVSQQLYNRQQKALQSMPIALSEYPMYSVPLRSYNLSNIANIRRMLYSDSITNEIRYQPITDSKSIDELVN
DLYTSGKRVVFTMGKGGVGKTTLATEIALKLTKLGAKVHLTTTDPANHLNYDFAIKSGITVSHIDEAEVLEKYKNEVRSK
AAETMTAEDMEYIEEDLRSPCTQEIAVFKAFAEIVDKAENEIVVIDTAPTGHTLLLLDATQSYHKEVERTQGEVTGAVAN
LLPRLRNPQETEVVIVTLPEATPVFEAERLQMDLQRAGINNKWWVVNACLSLTNTANSFLQAKAQSELTWIKKVEELSKG
NTALIEWKNL

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=301, Percent_Identity=26.9102990033223, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17557003, Length=269, Percent_Identity=27.5092936802974, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320103, Length=321, Percent_Identity=25.5451713395639, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586297, Length=316, Percent_Identity=26.2658227848101, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003593
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 62806; Mature: 62806

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFNLSDIELTKYLFFTGKGGVGKTSIACATAVGLADKGEKILLISTDPASNLQDVFNQ
CCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHH
TLNGHGTAISEVPGLTVVNLDPEQAAAEYRESVIAPFRGQLPESVIQNMEEQLSGSCTVE
HCCCCCCCHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
IAAFNEFSDFITDADKAKEYDHIIFDTAPTGHTLRMLQLPSAWSTFISESTHGASCLGQL
EEECHHHHHHHCCCHHHCCCCEEEEECCCCCCEEEEEECCHHHHHHHCCCCCHHHHHHHH
SGLEERKGIYKQAVDTLSDTSATRLVLVSRPEIAPLKEAARSSHELQLLGIKNQLLVING
CCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCCEEEEECCCCEEHHHH
VLQQLDEADNVSQQLYNRQQKALQSMPIALSEYPMYSVPLRSYNLSNIANIRRMLYSDSI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCHHHHHHHHHHHHHCCC
TNEIRYQPITDSKSIDELVNDLYTSGKRVVFTMGKGGVGKTTLATEIALKLTKLGAKVHL
CCCEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEE
TTTDPANHLNYDFAIKSGITVSHIDEAEVLEKYKNEVRSKAAETMTAEDMEYIEEDLRSP
EECCCCHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CTQEIAVFKAFAEIVDKAENEIVVIDTAPTGHTLLLLDATQSYHKEVERTQGEVTGAVAN
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
LLPRLRNPQETEVVIVTLPEATPVFEAERLQMDLQRAGINNKWWVVNACLSLTNTANSFL
HHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHH
QAKAQSELTWIKKVEELSKGNTALIEWKNL
HHHHHHHHHHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MKAFNLSDIELTKYLFFTGKGGVGKTSIACATAVGLADKGEKILLISTDPASNLQDVFNQ
CCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHH
TLNGHGTAISEVPGLTVVNLDPEQAAAEYRESVIAPFRGQLPESVIQNMEEQLSGSCTVE
HCCCCCCCHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
IAAFNEFSDFITDADKAKEYDHIIFDTAPTGHTLRMLQLPSAWSTFISESTHGASCLGQL
EEECHHHHHHHCCCHHHCCCCEEEEECCCCCCEEEEEECCHHHHHHHCCCCCHHHHHHHH
SGLEERKGIYKQAVDTLSDTSATRLVLVSRPEIAPLKEAARSSHELQLLGIKNQLLVING
CCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCCEEEEECCCCEEHHHH
VLQQLDEADNVSQQLYNRQQKALQSMPIALSEYPMYSVPLRSYNLSNIANIRRMLYSDSI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCHHHHHHHHHHHHHCCC
TNEIRYQPITDSKSIDELVNDLYTSGKRVVFTMGKGGVGKTTLATEIALKLTKLGAKVHL
CCCEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEE
TTTDPANHLNYDFAIKSGITVSHIDEAEVLEKYKNEVRSKAAETMTAEDMEYIEEDLRSP
EECCCCHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CTQEIAVFKAFAEIVDKAENEIVVIDTAPTGHTLLLLDATQSYHKEVERTQGEVTGAVAN
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
LLPRLRNPQETEVVIVTLPEATPVFEAERLQMDLQRAGINNKWWVVNACLSLTNTANSFL
HHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHH
QAKAQSELTWIKKVEELSKGNTALIEWKNL
HHHHHHHHHHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3021763; 1704144 [H]