Definition Bacteroides thetaiotaomicron VPI-5482 chromosome, complete genome.
Accession NC_004663
Length 6,260,361

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The map label for this gene is mdlB [C]

Identifier: 29345483

GI number: 29345483

Start: 69588

End: 71018

Strand: Reverse

Name: mdlB [C]

Synonym: BT_0073

Alternate gene names: 29345483

Gene position: 71018-69588 (Counterclockwise)

Preceding gene: 29345484

Following gene: 29345482

Centisome position: 1.13

GC content: 60.24

Gene sequence:

>1431_bases
ATGGATATGAAGGCGGGAATGAGTATGAAAGAAGGAGCGGAATGGCTGTGGAACGCCTCACGGGGATATCGCTCCCCCAT
TCTGGCGGGTATTCTTGCCGGGACAGTTCGCATCGGCGTGTCCCTCACGTTCGTCTGGTTCTGCAAGCACCTGATAGATA
CCGCCACCCATCAGGCGGACGGGAACATCATCCTGGGACTGGCGGCCATGGCGGGATGCATCGTCCTGCAACTGCTGCTG
TCCGCACTTGTCAGCCGTCTCTATGCGCACACGGAGATCAGCCTGCGCAACAGACTGCGGCAGGATCTGCTCGAACATAT
CCTGAAAAGCCGGTGGAACGGTCGCGAGACATTCCATTCCGGCGATATGCTCAACCGCATGGAGGAGGATGTCCGTACCG
TGACGGACCTGCTGGCGGGTTCCATCCCCTTGGTCGGAACCACGCTGTTCCAACTGGCCGGCGCCGCGCTGTTCCTGTTC
TGTCTCGACCGGCGGATGGCTGTCGTCATCCTGCTTATCATGCCGTTGGCGTTGCTGTGCAGCAAGCTCTACATGAAGCG
GATGCGGCGTCTGACACGTGAGATACGGGCGACGGACAGCCGTGTGCAAAGCCATCTGCAGGAGAACCTGCAGCACCGCA
CCCTGATTTCCGTCCTGGAATGCACCCCGGTGGCAGCGGACACGATGTCCTCACTCCAGTCGGGGCTGAAACGGCTGGTG
ATGCGGCGCAACTCATTTTCCATCTTTTCAAGTATCATGGTGCAGGCGGGGTTCGCCCTCGGCTATGTGACCGCTTTCGC
ATGGGGAATATACGGGCTGGACACCGGTACGGTAACATTCGGCACGCTGGCCGCCTTCCTGCAACTGGTGGCACAGGTAC
AACGCCCTGTCGTGGAGCTGGCCCGGCAGGTTCCGGTGTTTATCGGCGCACTGACTTCCGTGGAGAGGATAGACGAGCTC
AACTCCATGCCGCTGGAGGAACAGGGCGAGCCTGTCATCCTGGGTGGCAAGGCTGGTGTCCGTGTGGAGAATGTTACTTT
TACCTATCCCGGCGGCAGACGTAAGGTGCTGGAACATTTCACATACGATTTCAAGCCGGGGAGCCTGACCGCCGTGCTCG
GGGAGACCGGCAGCGGGAAGAGTACGCTGGTACGGCTGATACTGGCCTTGTTGCAGCCCGACGGGGGAAACATCACGCTG
TATGACAAGACCCGGCCCGTGCCCGTTTCTCCACTCACACGGGGGAATTTCGTGTATGTCCCGCAGGGGAATACGCTCGT
CAGCGGCACATTGCGCGACAACCTGCTGTTGGGCAATCCCGAAGCTACCGACGGGCAGATGCGGGAAGCGTTGCATACGG
CGGCGGCCGATTTTGTACGGGAACTGCCGCAAGGACTGGACACCCCTGCGGCGAGATGGGAACGGGCATAA

Upstream 100 bases:

>100_bases
GTTATGTGGACTGCGACGCAGGGGGTGAACGGTGCAAGGCGAAGATATGGGGCAGGCTGCTCCCTATTCGCCGGTATTTG
CTGTACATATACAGACGGGT

Downstream 100 bases:

>100_bases
GTGAGGGGCAGGCGCAACGCATAGCCATCGCGCGCGGACTGCTCCGCCCCGGTAACATCGTCCTGCTGGACGAGCCCACC
TCCTCGCTGGATTCCGATAC

Product: putative ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MDMKAGMSMKEGAEWLWNASRGYRSPILAGILAGTVRIGVSLTFVWFCKHLIDTATHQADGNIILGLAAMAGCIVLQLLL
SALVSRLYAHTEISLRNRLRQDLLEHILKSRWNGRETFHSGDMLNRMEEDVRTVTDLLAGSIPLVGTTLFQLAGAALFLF
CLDRRMAVVILLIMPLALLCSKLYMKRMRRLTREIRATDSRVQSHLQENLQHRTLISVLECTPVAADTMSSLQSGLKRLV
MRRNSFSIFSSIMVQAGFALGYVTAFAWGIYGLDTGTVTFGTLAAFLQLVAQVQRPVVELARQVPVFIGALTSVERIDEL
NSMPLEEQGEPVILGGKAGVRVENVTFTYPGGRRKVLEHFTYDFKPGSLTAVLGETGSGKSTLVRLILALLQPDGGNITL
YDKTRPVPVSPLTRGNFVYVPQGNTLVSGTLRDNLLLGNPEATDGQMREALHTAAADFVRELPQGLDTPAARWERA

Sequences:

>Translated_476_residues
MDMKAGMSMKEGAEWLWNASRGYRSPILAGILAGTVRIGVSLTFVWFCKHLIDTATHQADGNIILGLAAMAGCIVLQLLL
SALVSRLYAHTEISLRNRLRQDLLEHILKSRWNGRETFHSGDMLNRMEEDVRTVTDLLAGSIPLVGTTLFQLAGAALFLF
CLDRRMAVVILLIMPLALLCSKLYMKRMRRLTREIRATDSRVQSHLQENLQHRTLISVLECTPVAADTMSSLQSGLKRLV
MRRNSFSIFSSIMVQAGFALGYVTAFAWGIYGLDTGTVTFGTLAAFLQLVAQVQRPVVELARQVPVFIGALTSVERIDEL
NSMPLEEQGEPVILGGKAGVRVENVTFTYPGGRRKVLEHFTYDFKPGSLTAVLGETGSGKSTLVRLILALLQPDGGNITL
YDKTRPVPVSPLTRGNFVYVPQGNTLVSGTLRDNLLLGNPEATDGQMREALHTAAADFVRELPQGLDTPAARWERA
>Mature_476_residues
MDMKAGMSMKEGAEWLWNASRGYRSPILAGILAGTVRIGVSLTFVWFCKHLIDTATHQADGNIILGLAAMAGCIVLQLLL
SALVSRLYAHTEISLRNRLRQDLLEHILKSRWNGRETFHSGDMLNRMEEDVRTVTDLLAGSIPLVGTTLFQLAGAALFLF
CLDRRMAVVILLIMPLALLCSKLYMKRMRRLTREIRATDSRVQSHLQENLQHRTLISVLECTPVAADTMSSLQSGLKRLV
MRRNSFSIFSSIMVQAGFALGYVTAFAWGIYGLDTGTVTFGTLAAFLQLVAQVQRPVVELARQVPVFIGALTSVERIDEL
NSMPLEEQGEPVILGGKAGVRVENVTFTYPGGRRKVLEHFTYDFKPGSLTAVLGETGSGKSTLVRLILALLQPDGGNITL
YDKTRPVPVSPLTRGNFVYVPQGNTLVSGTLRDNLLLGNPEATDGQMREALHTAAADFVRELPQGLDTPAARWERA

Specific function: Unknown

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955966, Length=390, Percent_Identity=25.1282051282051, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI45243524, Length=390, Percent_Identity=25.1282051282051, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI73747915, Length=388, Percent_Identity=24.4845360824742, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI73747917, Length=388, Percent_Identity=24.4845360824742, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI171184400, Length=405, Percent_Identity=24.9382716049383, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI157502201, Length=433, Percent_Identity=26.5588914549654, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21536378, Length=403, Percent_Identity=24.0694789081886, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI134142337, Length=390, Percent_Identity=23.8461538461538, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI134142345, Length=390, Percent_Identity=23.8461538461538, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI134142340, Length=390, Percent_Identity=23.8461538461538, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI134142335, Length=390, Percent_Identity=23.8461538461538, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI134142342, Length=390, Percent_Identity=23.8461538461538, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI42490749, Length=224, Percent_Identity=29.4642857142857, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI9955970, Length=456, Percent_Identity=23.4649122807018, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI156105685, Length=397, Percent_Identity=22.9219143576826, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI9665248, Length=203, Percent_Identity=30.5418719211823, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI25914749, Length=131, Percent_Identity=35.8778625954198, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4557481, Length=391, Percent_Identity=25.3196930946292, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1786654, Length=464, Percent_Identity=24.5689655172414, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786653, Length=424, Percent_Identity=25.2358490566038, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1787143, Length=459, Percent_Identity=23.0936819172113, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787112, Length=351, Percent_Identity=26.2108262108262, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787113, Length=234, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788540, Length=320, Percent_Identity=23.125, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17533971, Length=490, Percent_Identity=24.4897959183673, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17558664, Length=398, Percent_Identity=23.3668341708543, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32563727, Length=319, Percent_Identity=21.9435736677116, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17511077, Length=319, Percent_Identity=21.9435736677116, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533592, Length=399, Percent_Identity=24.812030075188, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565938, Length=398, Percent_Identity=25.6281407035176, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17541710, Length=391, Percent_Identity=24.5524296675192, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567265, Length=413, Percent_Identity=23.0024213075061, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25146765, Length=383, Percent_Identity=23.4986945169713, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115534520, Length=230, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193202349, Length=403, Percent_Identity=26.7990074441687, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567269, Length=133, Percent_Identity=38.3458646616541, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17543740, Length=408, Percent_Identity=21.8137254901961, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86564969, Length=388, Percent_Identity=24.4845360824742, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17569145, Length=410, Percent_Identity=23.9024390243902, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71992066, Length=384, Percent_Identity=24.7395833333333, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71988343, Length=466, Percent_Identity=22.5321888412017, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567243, Length=407, Percent_Identity=23.3415233415233, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569081, Length=390, Percent_Identity=22.3076923076923, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=164, Percent_Identity=32.3170731707317, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=394, Percent_Identity=20.3045685279188, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=167, Percent_Identity=32.9341317365269, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=220, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=382, Percent_Identity=22.2513089005236, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=226, Percent_Identity=28.7610619469027, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321752, Length=406, Percent_Identity=22.4137931034483, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323217, Length=422, Percent_Identity=24.4075829383886, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324985, Length=419, Percent_Identity=20.0477326968974, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320339, Length=373, Percent_Identity=23.3243967828418, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322980, Length=380, Percent_Identity=21.3157894736842, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322640, Length=479, Percent_Identity=22.1294363256785, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322957, Length=129, Percent_Identity=31.7829457364341, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641565, Length=380, Percent_Identity=25.2631578947368, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397593, Length=476, Percent_Identity=25.4201680672269, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550390, Length=423, Percent_Identity=23.4042553191489, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653245, Length=462, Percent_Identity=22.0779220779221, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281363262, Length=149, Percent_Identity=32.8859060402685, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45552335, Length=400, Percent_Identity=21.75, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45552345, Length=400, Percent_Identity=21.75, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62484234, Length=411, Percent_Identity=22.3844282238443, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45552347, Length=400, Percent_Identity=22.25, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45552339, Length=400, Percent_Identity=22.75, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45552337, Length=400, Percent_Identity=22.25, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45552351, Length=400, Percent_Identity=22.75, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45552361, Length=377, Percent_Identity=22.2811671087533, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45552349, Length=377, Percent_Identity=22.2811671087533, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 52367; Mature: 52367

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDMKAGMSMKEGAEWLWNASRGYRSPILAGILAGTVRIGVSLTFVWFCKHLIDTATHQAD
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GNIILGLAAMAGCIVLQLLLSALVSRLYAHTEISLRNRLRQDLLEHILKSRWNGRETFHS
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
GDMLNRMEEDVRTVTDLLAGSIPLVGTTLFQLAGAALFLFCLDRRMAVVILLIMPLALLC
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLYMKRMRRLTREIRATDSRVQSHLQENLQHRTLISVLECTPVAADTMSSLQSGLKRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MRRNSFSIFSSIMVQAGFALGYVTAFAWGIYGLDTGTVTFGTLAAFLQLVAQVQRPVVEL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARQVPVFIGALTSVERIDELNSMPLEEQGEPVILGGKAGVRVENVTFTYPGGRRKVLEHF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHH
TYDFKPGSLTAVLGETGSGKSTLVRLILALLQPDGGNITLYDKTRPVPVSPLTRGNFVYV
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEE
PQGNTLVSGTLRDNLLLGNPEATDGQMREALHTAAADFVRELPQGLDTPAARWERA
ECCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
>Mature Secondary Structure
MDMKAGMSMKEGAEWLWNASRGYRSPILAGILAGTVRIGVSLTFVWFCKHLIDTATHQAD
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GNIILGLAAMAGCIVLQLLLSALVSRLYAHTEISLRNRLRQDLLEHILKSRWNGRETFHS
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
GDMLNRMEEDVRTVTDLLAGSIPLVGTTLFQLAGAALFLFCLDRRMAVVILLIMPLALLC
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLYMKRMRRLTREIRATDSRVQSHLQENLQHRTLISVLECTPVAADTMSSLQSGLKRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MRRNSFSIFSSIMVQAGFALGYVTAFAWGIYGLDTGTVTFGTLAAFLQLVAQVQRPVVEL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARQVPVFIGALTSVERIDELNSMPLEEQGEPVILGGKAGVRVENVTFTYPGGRRKVLEHF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHH
TYDFKPGSLTAVLGETGSGKSTLVRLILALLQPDGGNITLYDKTRPVPVSPLTRGNFVYV
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEE
PQGNTLVSGTLRDNLLLGNPEATDGQMREALHTAAADFVRELPQGLDTPAARWERA
ECCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]