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The map label for this gene is blh [H]

Identifier: 291481566

GI number: 291481566

Start: 2069469

End: 2070347

Strand: Direct

Name: blh [H]

Synonym: NA

Alternate gene names: 291481566

Gene position: 2069469-2070347 (Clockwise)

Preceding gene: 94314265

Following gene: 94314269

Centisome position: 80.21

GC content: 64.96

Gene sequence:

>879_bases
ATGACAACACAGATGGTCATCGAAGCCTTCTTCGACCCCGATACGTGGACCCTGAGCTACCTCGTGCTCGACCGTGAGAG
CCAGCAGTGCGCGATGATCGACAGCGTGCTCCACTACGACCCGAAATCCGGCCGTACCGGAACCGCCAGCGCAGACCGCA
TGATCGACCGCGTGCAGACGCTCGGCGCCAGCGTGCAGTGGATTCTGGAAACCCACGTACATGCCGACCATCTGTCCGCC
GCGCCCTACCTCAAGGCCAGGCTCGGCGGCCAGATCGCCATCGGCAGCCATATCACCACGGTGCAGAAGGTATTCGGCAC
GCTGTTCAACAGCGGCCCGGAGTTCGCGCATGACGGCAGTCAGTTCGACCGCCTGCTGCAGGACGGCGACACGCTCTCGA
TCGGCAGCCTGCAGGTGCGCGCGATGCACACCCCCGGCCACACACCGGCCTGCATGACGTACGTGATCAGCAACGGCAAG
GACACCGCCGCATTCGTTGGCGACACGCTGTTCATGCCCGACTACGGCACCGCCCGCTGCGATTTCCCCGGCGGCGATGC
GCGCACGCTCTACCGCTCCATCAACAAGGTGCTGAGCCTGCCCGCCGATACGCGCCTGTACATGTGCCACGACTACCAGC
CCGGCGGACGCGAGCTGCTGTTCATGTCCACGGTGGCGGAAGAGCGCGCCAGCAACATCCATGTGCGCGATGGCGTGAGC
GAGGACGAGTTCGTCGCGATGCGCCAGGCCCGCGACGCCACGCTGTCCATGCCCACGCTGATCCTGCCATCGGTGCAGGT
CAATATGCGCGCCGGAGAAATGCCGCCGCCGGAAGCCAACGGCACGCGCTATCTGAAGATCCCGATCAACGCGCTTTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: putative metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:
NA

Sequences:

>Translated_292_residues
MTTQMVIEAFFDPDTWTLSYLVLDRESQQCAMIDSVLHYDPKSGRTGTASADRMIDRVQTLGASVQWILETHVHADHLSA
APYLKARLGGQIAIGSHITTVQKVFGTLFNSGPEFAHDGSQFDRLLQDGDTLSIGSLQVRAMHTPGHTPACMTYVISNGK
DTAAFVGDTLFMPDYGTARCDFPGGDARTLYRSINKVLSLPADTRLYMCHDYQPGGRELLFMSTVAEERASNIHVRDGVS
EDEFVAMRQARDATLSMPTLILPSVQVNMRAGEMPPPEANGTRYLKIPINAL
>Mature_291_residues
TTQMVIEAFFDPDTWTLSYLVLDRESQQCAMIDSVLHYDPKSGRTGTASADRMIDRVQTLGASVQWILETHVHADHLSAA
PYLKARLGGQIAIGSHITTVQKVFGTLFNSGPEFAHDGSQFDRLLQDGDTLSIGSLQVRAMHTPGHTPACMTYVISNGKD
TAAFVGDTLFMPDYGTARCDFPGGDARTLYRSINKVLSLPADTRLYMCHDYQPGGRELLFMSTVAEERASNIHVRDGVSE
DEFVAMRQARDATLSMPTLILPSVQVNMRAGEMPPPEANGTRYLKIPINAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=273, Percent_Identity=31.1355311355311, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17538952, Length=258, Percent_Identity=28.2945736434109, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330176, Length=264, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32101; Mature: 31970

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQMVIEAFFDPDTWTLSYLVLDRESQQCAMIDSVLHYDPKSGRTGTASADRMIDRVQT
CCHHHEEEEHCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LGASVQWILETHVHADHLSAAPYLKARLGGQIAIGSHITTVQKVFGTLFNSGPEFAHDGS
HCCHHEEHHHHHCCHHHHCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCHH
QFDRLLQDGDTLSIGSLQVRAMHTPGHTPACMTYVISNGKDTAAFVGDTLFMPDYGTARC
HHHHHHHCCCEEEECCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCEEECCCCCCEEC
DFPGGDARTLYRSINKVLSLPADTRLYMCHDYQPGGRELLFMSTVAEERASNIHVRDGVS
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHCCEEEECCCC
EDEFVAMRQARDATLSMPTLILPSVQVNMRAGEMPPPEANGTRYLKIPINAL
HHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
TTQMVIEAFFDPDTWTLSYLVLDRESQQCAMIDSVLHYDPKSGRTGTASADRMIDRVQT
CHHHEEEEHCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LGASVQWILETHVHADHLSAAPYLKARLGGQIAIGSHITTVQKVFGTLFNSGPEFAHDGS
HCCHHEEHHHHHCCHHHHCCCCHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCHH
QFDRLLQDGDTLSIGSLQVRAMHTPGHTPACMTYVISNGKDTAAFVGDTLFMPDYGTARC
HHHHHHHCCCEEEECCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCEEECCCCCCEEC
DFPGGDARTLYRSINKVLSLPADTRLYMCHDYQPGGRELLFMSTVAEERASNIHVRDGVS
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHCCEEEECCCC
EDEFVAMRQARDATLSMPTLILPSVQVNMRAGEMPPPEANGTRYLKIPINAL
HHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]