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The map label for this gene is dtpB [H]

Identifier: 29144195

GI number: 29144195

Start: 4061730

End: 4063199

Strand: Reverse

Name: dtpB [H]

Synonym: t3924

Alternate gene names: 29144195

Gene position: 4063199-4061730 (Counterclockwise)

Preceding gene: 29144196

Following gene: 29144191

Centisome position: 84.79

GC content: 50.75

Gene sequence:

>1470_bases
ATGAATACAACTGCACCTACGGGCTTGCTGCAGCAACCTCGTCCATTCTTCATGATCTTTTTTGTAGAATTATGGGAACG
ATTTAGCTATTACGGCGTCCAGGGCATCCTGGCGGTCTTTTTCGTTAAACAATTGGGTTTTTCTCAGGAACAGGCCTTTA
TTACTTTTGGCGCTTTTGCGGCGCTGGTTTATGGCCTGATCTCCATCGGCGGCTATGTTGGCGACCATCTGTTAGGGACT
AAACGCACCCTGGTCCTGGGCGCGATTGTGCTGGCGATTGGCTATTTTATGACTGGTATGTCGCTATTAAATCCCGATCT
GATTTTTATCGCACTGGGTACGATTGCCGTGGGCAACGGGTTATTTAAAGCCAATCCCGCCAGCCTGCTCTCTAAATGCT
ATCAGCCTAAAGATCCCCGGCTGGATGGCGCTTTCACCCTGTTTTATATGTCGATTAACATCGGTTCTTTGTTATCGCTA
TCGCTGGCGCCGGTGATTGCCGATAAATTTGGCTATGCGGTGACCTATAATCTGTGCGGCGCTGGTTTAATTGTTGCGCT
TCTGGTGTACTTCGCCTGCCGTGGCATGGTGAAAAATATCGGTTCTGAACCGGATCATAAACCGCTACGTTTTCGCAATT
TGCTGCTGGTACTACTCGGCACCGTCGTCATGATTTTCCTCTGCGCCTGGCTGATGCACAACGTTAAGATTGCCAATCTG
GTGCTCATCGTCCTTTCTATCGTCGTCACTATTTTCTTCTTTCGCGAAGCGTTTCGTCTGGATAAAACCGGCCGCAATAA
AATGTTCGTGGCGTTTATTCTGATGATTGAAGCCGTGCTGTTTTACATTCTGTATGCGCAGATGCCTACCTCACTGAACT
TCTTTGCGATTAATAACGTGCATCATGAAATTCTTGGATTCGCCATTAACCCGGTGAGTTTTCAGGCGCTGAACCCATTC
TGGGTGGTCGTCGCCAGTCCGGTACTGGCAGCGATTTACACCCGACTGGGTAGCAAAGGCAAAGATCTGACTATGCCGAT
GAAGTTTACGCTCGGCATGTTCCTCTGCGCGCTGGGTTTTCTGACCGCCGCCGCCGGGATGTGGTTTGCCGATGCGCAAG
GATTGACGTCGCCGTGGTTTATCGTGCTAGTGTATCTGTTCCAGAGTCTGGGCGAGTTGCTGATTAGCGCGCTGGGACTG
GCAATGGTCGCCGCTCTGGTGCCGCAGCATCTGATGGGCTTTATTCTGGGAATGTGGTTCCTGACCCAGGCCGCCGCCTT
CCTGCTCGGCGGTTATGTGGCGACCTTCACTGCCGTACCGGAAAACATCACCGATCCGTTACAGACGCTGCCCATTTATA
CCGGCGTCTTTAGCAAAATTGGTCTGGTAACGCTGGCGGTCACCGTGGTGATGGCCATTATGGTGCCGTGGTTAAACCGA
ATGATTAATACGCAAGGTACCGAACAGTAA

Upstream 100 bases:

>100_bases
ATCAGGCTAATAACCGCAGTCTATATCAGGGTAAGACTTTTCGGCGCGTTTTGATATACGCGTTCATACGTTTCGGGATG
GCATTAAAAGGCGAAGGAAT

Downstream 100 bases:

>100_bases
TACTCAGTGCCGGATGCGGCTTACGCCTTATCCGGCCTACAAATAATTGAGAATCGTAGGCCCGATAAGCGTAGCGCCAT
CGGGCAATCCGTTACTCCGT

Product: inner membrane transporter YhiP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFSYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANL
VLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGL
AMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNR
MINTQGTEQ

Sequences:

>Translated_489_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFSYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANL
VLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGL
AMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNR
MINTQGTEQ
>Mature_489_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFSYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANL
VLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPF
WVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGL
AMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNR
MINTQGTEQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=389, Percent_Identity=23.6503856041131, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI226371746, Length=358, Percent_Identity=25.1396648044693, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226371748, Length=350, Percent_Identity=24.8571428571429, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789911, Length=489, Percent_Identity=87.5255623721881, Blast_Score=878, Evalue=0.0,
Organism=Escherichia coli, GI1787922, Length=471, Percent_Identity=52.2292993630573, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1786927, Length=437, Percent_Identity=26.5446224256293, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1790572, Length=469, Percent_Identity=28.1449893390192, Blast_Score=165, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17541704, Length=391, Percent_Identity=24.2966751918159, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17569141, Length=202, Percent_Identity=28.2178217821782, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571098, Length=212, Percent_Identity=25.4716981132075, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571102, Length=204, Percent_Identity=25.9803921568627, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571100, Length=204, Percent_Identity=25.9803921568627, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24639583, Length=342, Percent_Identity=24.2690058479532, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639585, Length=331, Percent_Identity=24.4712990936556, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639581, Length=331, Percent_Identity=24.4712990936556, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53661; Mature: 53661

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCC
>Mature Secondary Structure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HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]