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The map label for this gene is sgbE [H]

Identifier: 29144121

GI number: 29144121

Start: 3968932

End: 3969627

Strand: Reverse

Name: sgbE [H]

Synonym: t3842

Alternate gene names: 29144121

Gene position: 3969627-3968932 (Counterclockwise)

Preceding gene: 29144122

Following gene: 29144119

Centisome position: 82.84

GC content: 59.05

Gene sequence:

>696_bases
ATGTTAGAGCAACTGAAAGCCGAGGTGCTGGCGGCCAACCTGGCCCTCCCGGCGCACGGGCTGGTCACCTTTACCTGGGG
CAACGTCAGCGCGGTCGATGAGACGCGCAAGCTGATGGTCATTAAGCCTTCCGGCGTCGAATATGAGGTGATGACCGCCG
ACGATATGGTGGTGGTAGAGATCGCCAGCGGTAAGGTCGTTGAAGGCAACAAAAAACCGTCGTCCGATACCGCGACCCAT
CTGGCGCTCTATCGCCGCTATCCGCAGATCGGTGGGATCGTGCATACCCATTCCCGCCATGCGACGATCTGGTCGCAGGC
CGGGCTCGATCTGCCCGCCTGGGGCACCACCCACGCCGACTATTTCTATGGCGCGATCCCCTGTACCCGGCTGATGACCG
TTGAGGAAATTAACGGCGAGTACGAGTATCAGACCGGCGAGGTGATTATTAAAACCTTTGAAGAGCGCGGTCTCGATCCG
GCGCAAATCCCGGCGGTATTAGTTCATTCACACGGCCCGTTTGCCTGGGGTAAAAATGCCGCCGATGCCGTCCACAACGC
CGTGGTGCTTGAGGAGTGCGCCTATATGGGGCTGTTCTCGCGCCAGCTGGCCCCGCAGCTACCGGATATGCAGCCGGAAT
TGCTCGATAAACACTATCTGCGTAAACATGGCGCGAACGCCTATTACGGGCAGTAA

Upstream 100 bases:

>100_bases
TTCTGATTGAGATGTGGACAGAGAAAGCCAGCGAGCCGGTGCTGGAAATTATCCAGGCCCGCCGCTGGATTGAATCACGG
ATGCAGGAAGGAGGTTTCAC

Downstream 100 bases:

>100_bases
TATCGGCAGTCACAGCCTGTGTCGGATGGCGGCTGCGCCTTATCCGACCTACAAGATTTGCAATATCAATACGTTGTGAT
GAACTCTTGTAGGCCCGATA

Product: L-ribulose-5-phosphate 4-epimerase

Products: NA

Alternate protein names: Phosphoribulose isomerase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVEIASGKVVEGNKKPSSDTATH
LALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKHYLRKHGANAYYGQ

Sequences:

>Translated_231_residues
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVEIASGKVVEGNKKPSSDTATH
LALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKHYLRKHGANAYYGQ
>Mature_231_residues
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVEIASGKVVEGNKKPSSDTATH
LALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKHYLRKHGANAYYGQ

Specific function: Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790008, Length=231, Percent_Identity=93.0735930735931, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI1786247, Length=231, Percent_Identity=76.6233766233766, Blast_Score=375, Evalue=1e-106,
Organism=Escherichia coli, GI1790642, Length=230, Percent_Identity=63.0434782608696, Blast_Score=303, Evalue=7e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004661 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =5.1.3.4 [H]

Molecular weight: Translated: 25486; Mature: 25486

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVE
CHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCEEEEECCCCCEEEEEECCCEEEEE
IASGKVVEGNKKPSSDTATHLALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHAD
ECCCEEEECCCCCCCHHHHHHHHHHHCHHHCCEEEECCCCEEEHHHCCCCCCCCCCCCCC
YFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDPAQIPAVLVHSHGPFAWGKNA
CEECCCCHHHEEEHHHCCCEEEEECCHHHEEEHHHHCCCHHHCCEEEEECCCCCCCCCCH
ADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKHYLRKHGANAYYGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPSGVEYEVMTADDMVVVE
CHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCEEEEECCCCCEEEEEECCCEEEEE
IASGKVVEGNKKPSSDTATHLALYRRYPQIGGIVHTHSRHATIWSQAGLDLPAWGTTHAD
ECCCEEEECCCCCCCHHHHHHHHHHHCHHHCCEEEECCCCEEEHHHCCCCCCCCCCCCCC
YFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDPAQIPAVLVHSHGPFAWGKNA
CEECCCCHHHEEEHHHCCCEEEEECCHHHEEEHHHHCCCHHHCCEEEEECCCCCCCCCCH
ADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKHYLRKHGANAYYGQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 11741871 [H]