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The map label for this gene is gudP [H]

Identifier: 29143981

GI number: 29143981

Start: 3799074

End: 3800336

Strand: Reverse

Name: gudP [H]

Synonym: t3687

Alternate gene names: 29143981

Gene position: 3800336-3799074 (Counterclockwise)

Preceding gene: 29143986

Following gene: 29143980

Centisome position: 79.31

GC content: 47.66

Gene sequence:

>1263_bases
ATGTCGATGGCCCTTACCGCCCCGCCTGGCAGGAAAAGATTTTTAATCGTTGCCTGTCTGTTTATTGGAATATTCATTGC
CTATCTCGACCGCGTTAATGTTTCGGTATTAGCCGCAAACGAACCCTTCTTAGCCTATATGGGTATTGAAGGCATGCCAT
TGCAAATTGGCATGATGATGACCGTTTTTCTTGCCGCTTATGGTATCGCTAATGTTGTATTATCACCACTTGGCGACTAC
CTTGGTCCGAGAAAAGCGATGATGCTTTGTATCCTAATCTGGACCATCGCCTTAATTATTGGCGGAGTTGCGACATCGTT
TGCATTAATTATTATTTGCCGCATATTACTGGGTATCGGAGAGGGTTTTTATTATCCGCTGCAAAGCGTATTTATTAAAA
ACTGGTTTCCGAAGCAGGAGCGTGGCCGGGCAAACGCAGCGTGGATCGTCGGCCAGTCGGTCGCGCCCGCCATTGCGATG
CCTTTTTTCACCTGGTGGATAGGCACCCACGGCTGGCGTTCCAACTTCTTTTTATGCGCCGCTCTCGGGTTAATCCCACT
CTGGCTACTTTGGCGATATGTTGCTGATAAACCAGAACAACATAAAAGTATCAGCGAGCAGGAACTGGCTTATATCAAAG
CCGGGCAGGAAACGGAAAGCGCAAGCAGCAGCGAAAGTTTTATGTTGCGGGTAAAACCGGTGATTACCAACTATTGCTAC
TGGTTGCTGGTGCTGTGGTACCTGTGTCTGCAATGCCTGTACTGGGGGATGATTACCTGGCTGCCAACCTATCTTAAATC
AGCCAGAGGATTTAGCTGGGCAGAAATGGGCTGGCTAGCGTCGCTGCCGTTTGTCTTGTCGATATTTTCCAAAGCCGCCG
CGGGCGTCTTCGTCGATAAAATAGGACGCAGCGCCCCCATATTAATGGTGTTAATGTTTTTCGCCGGTATCAGTATCTAT
TTCGGCACAATAACCGAACACAAATATATGTCAGCGGTACTACTCTCCTTCGCCGTCGCTTTTTGCACGATGGGTACGCC
TGTTGCGTGGACATTATTACAAGGGATGGTGTCCGGGAAATCTATTTCCGCCGCCAGCGGCGTAATGAACGGCGTCGCGA
ACGGCCTGTCATCATTATCACCAGTATTTATCGGTTTATTTATCTCTATTACAGGAACCTATACCGGCGGCTTATTATGT
CTGGTTTTCATCAGCGCTATCGCCGTGGTATCTGCATTCGTTTTAACGATTAAAAAATATTAA

Upstream 100 bases:

>100_bases
CCGTTTTTCTAATCTCATCGATATTGTTACCCTGGTCATGAATCACCCTATTGTAAAAATAAACAAAAATGATGTTAATT
TAATTAAAGGAGATCGCCAA

Downstream 100 bases:

>100_bases
TCACAAGGAGTAAATGATGAAAATTACCAGCATTGATATTATTGATGTTGCTAATGATTTTGCGTCCGCCACCAGCAAAT
GGCGTCCGGTGGTGGTAAAA

Product: membrane transport protein

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDY
LGPRKAMMLCILIWTIALIIGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESASSSESFMLRVKPVITNYCY
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGVFVDKIGRSAPILMVLMFFAGISIY
FGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMVSGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLC
LVFISAIAVVSAFVLTIKKY

Sequences:

>Translated_420_residues
MSMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDY
LGPRKAMMLCILIWTIALIIGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESASSSESFMLRVKPVITNYCY
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGVFVDKIGRSAPILMVLMFFAGISIY
FGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMVSGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLC
LVFISAIAVVSAFVLTIKKY
>Mature_419_residues
SMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDYL
GPRKAMMLCILIWTIALIIGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMP
FFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESASSSESFMLRVKPVITNYCYW
LLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGVFVDKIGRSAPILMVLMFFAGISIYF
GTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMVSGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCL
VFISAIAVVSAFVLTIKKY

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=318, Percent_Identity=23.5849056603774, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI9966811, Length=359, Percent_Identity=23.6768802228412, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI9945322, Length=193, Percent_Identity=25.3886010362694, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789152, Length=429, Percent_Identity=26.1072261072261, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI2367379, Length=407, Percent_Identity=27.027027027027, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI87082320, Length=428, Percent_Identity=26.8691588785047, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789515, Length=413, Percent_Identity=23.0024213075061, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082071, Length=432, Percent_Identity=23.1481481481481, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI2367193, Length=276, Percent_Identity=24.6376811594203, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082404, Length=214, Percent_Identity=24.2990654205607, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=241, Percent_Identity=26.5560165975104, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25141318, Length=241, Percent_Identity=26.5560165975104, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17569727, Length=305, Percent_Identity=26.8852459016393, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25141316, Length=241, Percent_Identity=26.5560165975104, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25141341, Length=261, Percent_Identity=26.8199233716475, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI32567120, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561502, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561498, Length=210, Percent_Identity=25.7142857142857, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534558, Length=210, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533554, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560966, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=332, Percent_Identity=22.5903614457831, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=274, Percent_Identity=21.5328467153285, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=236, Percent_Identity=22.8813559322034, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17561500, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534562, Length=232, Percent_Identity=25.4310344827586, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193208223, Length=209, Percent_Identity=26.7942583732057, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=239, Percent_Identity=23.0125523012552, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=258, Percent_Identity=24.4186046511628, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=203, Percent_Identity=23.1527093596059, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=203, Percent_Identity=23.1527093596059, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=258, Percent_Identity=24.4186046511628, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641682, Length=269, Percent_Identity=25.6505576208178, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI45550460, Length=417, Percent_Identity=23.021582733813, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19922400, Length=304, Percent_Identity=23.3552631578947, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654215, Length=319, Percent_Identity=23.1974921630094, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580790, Length=257, Percent_Identity=23.7354085603113, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130167, Length=310, Percent_Identity=24.1935483870968, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583789, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648416, Length=304, Percent_Identity=23.0263157894737, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356189, Length=304, Percent_Identity=23.0263157894737, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655255, Length=309, Percent_Identity=22.9773462783171, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573299, Length=402, Percent_Identity=23.6318407960199, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20130135, Length=409, Percent_Identity=22.2493887530562, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655271, Length=409, Percent_Identity=22.2493887530562, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46148; Mature: 46017

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCHHHHHHH
TVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALIIGGVATSFALIIICRILLGIG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMPFFTWWIGTHGWRSNFFLCA
CCHHHHHHHHHHHHCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESASSSESFMLRVKPVITNYCY
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHH
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGVFVDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRSAPILMVLMFFAGISIYFGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMVSGK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCLVFISAIAVVSAFVLTIKKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCHHHHHHH
TVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALIIGGVATSFALIIICRILLGIG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMPFFTWWIGTHGWRSNFFLCA
CCHHHHHHHHHHHHCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESASSSESFMLRVKPVITNYCY
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHH
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFSKAAAGVFVDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRSAPILMVLMFFAGISIYFGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMVSGK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCLVFISAIAVVSAFVLTIKKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]