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The map label for this gene is cyaD [H]

Identifier: 29143015

GI number: 29143015

Start: 2733252

End: 2734415

Strand: Direct

Name: cyaD [H]

Synonym: t2646

Alternate gene names: 29143015

Gene position: 2733252-2734415 (Clockwise)

Preceding gene: 29143014

Following gene: 29143016

Centisome position: 57.04

GC content: 53.35

Gene sequence:

>1164_bases
ATGGACGATTTCGATATTCAGCGTGAACGGGCGTTTTCCGGCGCGGGTCGTATTGTTCTGATCTGCTCACTGTTATTTCT
CATTCTCGGCATCTGGGCGTGGTTTGGCCGACTGGATGAGGTTTCCACCGGCAACGGGAAAGTAATCCCCAGTTCACGCG
AACAGGTTCTGCAGTCGCTGGATGGCGGCATTCTGGCGCAGTTGACGGTGCGGGAAGGCGACAGAGTTCAGGCTAACCAG
ATTGTCGCCCAGCTTGATCCGACGCGTCTGGCGTCCAATGTTGGTGAAAGTGCGGCAAAATATCGCGCTTCACTCGCCTC
CAGCGCACGGTTAACCGCGGAAGTCAGCGACTTACCTCTCGCCTTCCCCGCTGAGCTGAACGGCTGGCCGGATCTGATTG
CCGCAGAGACGCGTCTCTATAAAAGCCGCCGCGCGCAGCTGGCCGATACCGAAGCCGAGCTACGGGATGCGCTGGCGTCG
GTTAATAAAGAGCTGACCATTACCCAGCGGCTGGAGAAAAGCGGCGCGGCCAGTCATGTTGAAGTGCTACGCCTGCAACG
ACAAAAAAGCGATTTAGGCTTAAAAATTACCGATCTGCGCTCACAATATTATGTGCAGGCACGCGAAGCGTTATCAAAAG
CGAACGCTGAGGTCGATATGCTCTCCGCCATTTTAAAAGGACGCGAGGATTCCGTCACCCGCCTTACCATACGTTCGCCG
GTACGCGGCATTGTTAAAAATATCCAGGTCACGACGATTGGCGGCGTGATCCCGCCTAACGGTGAGATGATGGAGATAGT
GCCGGTAGACGATCGTCTGTTGATTGAAACCCGCCTTTCGCCGCGTGATATCGCCTTTATTCATCCCGGCCAACGCGCAT
TGGTTAAAATTACTGCTTACGATTACGCCATTTACGGCGGGCTTGACGGCGTGGTGGAGACCATTTCACCGGATACCATT
CAGGATAAAGTGAAACCGGAAATTTTCTACTATCGCGTGTTTATCCGCACCCACCAGGACTATCTACAAAATAAATCAGG
ACGCCGTTTTTCGATTGTTCCAGGCATGATCGCCACGGTGGATATCAAAACCGGTGAAAAAACCATTGTCGACTATTTAA
TCAAACCGTTTAATCGCGCGAAAGAAGCGCTGCGCGAGCGGTAA

Upstream 100 bases:

>100_bases
CTGGTGATGGACGCGCCAAAAGCGCAGGCGCTTAACGCGGATCGGATGCAAAGTCACCGTCGGGAGTAGAAAAATGAAAA
TCAATCAGCATGATGCCGCG

Downstream 100 bases:

>100_bases
ATCGCTGAAGATAAGAAGATACGGGGGCTGGTCACGCGTGTCACAAGTCTGTTATACTTACCTTACACATTGGGGCTGAT
TCTGGATTCGACGGGATTTG

Product: type I secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQLTVREGDRVQANQ
IVAQLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALAS
VNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDSVTRLTIRSP
VRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGVVETISPDTI
QDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER

Sequences:

>Translated_387_residues
MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQLTVREGDRVQANQ
IVAQLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALAS
VNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDSVTRLTIRSP
VRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGVVETISPDTI
QDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER
>Mature_387_residues
MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQLTVREGDRVQANQ
IVAQLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALAS
VNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDSVTRLTIRSP
VRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGVVETISPDTI
QDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER

Specific function: CyaD is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43020; Mature: 43020

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSL
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHC
DGGILAQLTVREGDRVQANQIVAQLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPL
CCCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCE
AFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALASVNKELTITQRLEKSGAASHV
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHH
EVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDSVTRLTIRSP
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEHHH
VRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAY
HHHHHHCCEEEEECCEECCCCCEEEEEECCCEEEEEECCCCCCEEEECCCCEEEEEEEEE
DYAIYGGLDGVVETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATV
EEEEECCHHHHHHHCCCCHHHHHCCCEEEEEEEEHHHHHHHHCCCCCCEEEECCCEEEEE
DIKTGEKTIVDYLIKPFNRAKEALRER
EECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTGNGKVIPSSREQVLQSL
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHC
DGGILAQLTVREGDRVQANQIVAQLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPL
CCCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCE
AFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALASVNKELTITQRLEKSGAASHV
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHH
EVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEVDMLSAILKGREDSVTRLTIRSP
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEHHH
VRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAY
HHHHHHCCEEEEECCEECCCCCEEEEEECCCEEEEEECCCCCCEEEECCCCEEEEEEEEE
DYAIYGGLDGVVETISPDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATV
EEEEECCHHHHHHHCCCCHHHHHCCCEEEEEEEEHHHHHHHHCCCCCCEEEECCCEEEEE
DIKTGEKTIVDYLIKPFNRAKEALRER
EECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2905265; 12910271 [H]