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The map label for this gene is nanM [H]

Identifier: 29142221

GI number: 29142221

Start: 1850105

End: 1851259

Strand: Reverse

Name: nanM [H]

Synonym: t1790

Alternate gene names: 29142221

Gene position: 1851259-1850105 (Counterclockwise)

Preceding gene: 29142226

Following gene: 29142220

Centisome position: 38.63

GC content: 40.26

Gene sequence:

>1155_bases
ATGGGGATGCAGATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTATCAGTTGCTATCACCACATCAGG
ATATGCAACCACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACTGGCGCTATTGATAATAATGGCGTGATTTATG
TCGGCTTAGGTACCGCAGGGACATCCTGGTATAAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCG
TTTCCTGGTGGAGCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATAAGCTGTATGTTTTTGGTGGCGTAGGGAAAAA
AAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCACCGGTGAAAAATACATGGCAAAAAGTTGATA
CTATATCTCCAGTTGGATTAACAGGGCATACGGGAGTAAAATTAAACGAAACGATGGTACTTATTACCGGAGGGGTTAAT
GAGCATATCTTTGATAAGTATTTTATTGATATAGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATCTATAATTATTT
TAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTACAATGCTAAAGAGAACACATGGAAGAATGCCG
GTGAGCTGCCAGGCGCGGGGACGGCAGGATCGTCATCGGTAATGGAAAATAATTTCTTGATGCTGATTAATGGTGAGCTC
AAACCGGGTTTACGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAGAACAGCCAGTT
ACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTTTCGGGCTATAGCCACGGTGTCCTGCTTGTCG
GTGGTGGCGCGAATTTTCCGGGAGCAAAACAAAATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAATAAAAAA
TGGCGAGATGAAGTCTATGGTTTGATTAATGGCCATTGGCAATATATGGGTAAAATGAAACAACCTCTCGGCTATGGTGT
ATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCTAAAGGGAAACCTGTTTCGTCTGTAACCTCCT
TTACCATGCGTGATGGTAATTTATTAATAAAATAA

Upstream 100 bases:

>100_bases
TTATTTTTAGCGCTTGGTCACATTTTGTCATTTTCATTGTTGAAATTATGCACCATAAGATCACTAATGATGAAGCTTTA
CTCCAGTTGTATTTCTTCGC

Downstream 100 bases:

>100_bases
TTTTTTAAATACAAAAATAAAGTTAATTGATAAGCGGAGTATTTTATGAAAATCAACAGATATCTTCTGGGTATGGTTTC
GTTTATAGCATTTTCATCAT

Product: N-acetylneuraminic acid mutarotase

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase; Neu5Ac mutarotase; Sialic acid epimerase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKS
FPGGAREQSVSVFLNDKLYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVN
EHIFDKYFIDIAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMENNFLMLINGEL
KPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKK
WRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK

Sequences:

>Translated_384_residues
MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKS
FPGGAREQSVSVFLNDKLYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVN
EHIFDKYFIDIAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMENNFLMLINGEL
KPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKK
WRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK
>Mature_383_residues
GMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSF
PGGAREQSVSVFLNDKLYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNE
HIFDKYFIDIAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMENNFLMLINGELK
PGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKKW
RDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

Organism=Escherichia coli, GI87082419, Length=374, Percent_Identity=40.9090909090909, Blast_Score=295, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 42387; Mature: 42256

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCCCCCCEEEEEECCCC
TSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDKLYVFGGVGKKNSESPLQVYSDVY
CEEEEEEEHHHCCHHHHHHCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHH
KYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIAAADESEKN
HCCCCHHHHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCHHHHHEEEEEEEECCCCCCC
KVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMENNFLMLINGEL
CEEEECCCCCHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
KPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFP
CCCCCHHEEEEEEECCCCEEEEECCCCCCCCCCHHHHCCHHHCCCCCCCEEEEECCCCCC
GAKQNYTNGKFYSHEGINKKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGG
CCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCEEEEEEC
ENAKGKPVSSVTSFTMRDGNLLIK
CCCCCCCCHHHEEEEEECCCEEEC
>Mature Secondary Structure 
GMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAG
CCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCCCCCCEEEEEECCCC
TSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDKLYVFGGVGKKNSESPLQVYSDVY
CEEEEEEEHHHCCHHHHHHCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHH
KYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIAAADESEKN
HCCCCHHHHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCHHHHHEEEEEEEECCCCCCC
KVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMENNFLMLINGEL
CEEEECCCCCHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
KPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFP
CCCCCHHEEEEEEECCCCEEEEECCCCCCCCCCHHHHCCHHHCCCCCCCEEEEECCCCCC
GAKQNYTNGKFYSHEGINKKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGG
CCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCEEEEEEC
ENAKGKPVSSVTSFTMRDGNLLIK
CCCCCCCCHHHEEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA