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The map label for this gene is yeeJ [C]

Identifier: 29142013

GI number: 29142013

Start: 1631872

End: 1633854

Strand: Reverse

Name: yeeJ [C]

Synonym: t1573

Alternate gene names: 29142013

Gene position: 1633854-1631872 (Counterclockwise)

Preceding gene: 29142014

Following gene: 29142012

Centisome position: 34.1

GC content: 50.98

Gene sequence:

>1983_bases
GTGGTTTTTTCTAAAAAACCCATTACTAAATATATAACCTGGGCCATTGTTACCAGTCAGATTCCACTGCCGGTCATCGC
TGATAGCGATAATGAAATTCAGTCATGGATTGCAGGGACGGCATCGTCTATTTCTCCGCATCTGCAGGAGGGGACGCTGG
AGGATTATGCCAAAGGAAAAATAAAGGCATTACCAGGGCAAGCCGCTAATCATCTGGTGAACGAGGGGATGAAGAGCGCT
TTTCCGGAGATTATTTTCCGTGGTGGCGTCAATCTTGAAGATGGCGCGAAATATCGCTCATCAGAGTTCGATATGTTTAT
TCCCGTCCAGGAAACAACATCGTCTTTACTCTTTGGCCAGCTTGGCTTTCGCGACCACGACAGCAGCAGTTTCGATGGCC
GCACCTATGTTAACGTTGGTGTGGGTTATCGCCAGGAGGTCAATGGATGGCTGCTCGGCGTCAATACGTTTCTGGATGCC
GACATCCGTTATTCCCACTTGCGTGGCGGCATTGGCGGGGAAGTCTATAAAGACAGTCTGGCCTTTTCCGGCAACTATTA
TTTCCCTCTCACCGGCTGGAAAACGTCAGTAGTTCATGAATTACATGATGAGCGTCCGGCATATGGCTTTGATCTGCGAA
CAAAAGGCACGCTTCCCGATTTTCCCTGGTTCAGTGGCGAGCTGACATATGAACAGTATTACGGGGATAAAGTTGATCTA
TTGGGTAACGGTACATTAAGCCGGAATCCCCGCGCCGCAGGTGCGGCTCTGGTCTGGAATCCTGTCCCCTTGCTTGAGGT
CAGAGCAGGATATCGGGACGCCGGTAACGGCGGATCGCAGGCAGAGGGCGGTCTGAGAGTCAACTATTCCTTCGGTACGC
CGTTACATGAACAGCTTGATTACCGCAACGTTGGGGCGCCGTCGAATACGACTAATCGGCGTGCCTTTGTCGATCGTAAT
TACGATATCGTCATGGCGTATCGGGAGCAGGCCAGTAAAATCCGCATTATGGCAATGCCGGTGTCAGGCCTGTCCGGGAC
GCTGGTGATATTAATGGCGACGGTAGATAGCCGTTACCCGATTGAGAAAGTTGAGTGGTCGGGTGATGCGGAACTTCTCG
CCGGACTTCAGCTTCAGGGGAGTTTGGGCAGCGGCCTTATCCTTCCTCAACTTCCGCTGACGGCGACCGACGGTCAGGAG
TATAGCCTTTATTTAACGGTGACTGACAGCCGGGGTACTCGCGTGACCTCCGAGCGTATCCCGGTAAGGGTGACACAGGA
TGAGACCAGTTTCCGTTCCTGGATAAATGTTATCAATGACGATGTTCAGGTTGAGGACGGCAACTTTGTTATCAGTACGC
CGCTTCCTGCCGGAGAAGAGGGGAAGGTTATTGAGTGGCACTACGTGCGCGAGCGTTCTGAAGAGGAGTGGGCGTCGCTC
AAACCACGTCATATTAAGTATCAATCAGATACGCCGGGTCTGGCATTTAAAGCGCTCGGTGGTACAGAGCGTGACGGCCA
TTGGGTTGAACGGGTTCTGGTGACCCATATCGGCGATGATGCCCGCTCGCTCAAATTACATATTGAAGCAAGCGGACCAG
ACGATAAACATCCGGTGAAGGGTACCGTACTACTACAAGCGCAGTCAGACAGTATTGCGCAGAAGGTCACTTCTGTGGAG
GTGCTTTTTACGCAGGGTACTGAAGAAGCCAACGGAAGCGTTACTGCGCCAGTCGTCGGAACAGAAATGCGAGCCAGAAC
GCTTTGTGTAAATAACACGGACTGTACTGATGCGTTTAATTATCAGTGGGAAATCTCGGATGAAATGAAATCCTGGCAAT
CCGTACCGGGGGCGACAAAGGCCACCTGGCTTCTTCCTTATAGTCTTAATGGGGAATCGCTTCAGAATAAATATATCCGC
GTCAGAATTATTTCTGATAAGGGAAATGCTAAGGGTAATACCGCAACCTCTGATGCGAATTAA

Upstream 100 bases:

>100_bases
AGAATAAACGCGCTATCCGTCGCTGATGGTTATCGCCAAATAAACATCTTATTTAAATACTCCCTCTGCCAGGCAGGGGG
ATATAGCAGGAGACAATAAA

Downstream 100 bases:

>100_bases
TGTTTTAAAAAGGATCAACAGTGCGTATGTCGAAACATAATCTTATTATCTATAGCCTGCTTCTGGCGGCTGTGCCGATA
AGCGTCTTGGCGGATTCGTC

Product: invasin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGKIKALPGQAANHLVNEGMKSA
FPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQLGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDA
DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRN
YDIVMAYREQASKIRIMAMPVSGLSGTLVILMATVDSRYPIEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQE
YSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFVISTPLPAGEEGKVIEWHYVRERSEEEWASL
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVE
VLFTQGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIR
VRIISDKGNAKGNTATSDAN

Sequences:

>Translated_660_residues
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGKIKALPGQAANHLVNEGMKSA
FPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQLGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDA
DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRN
YDIVMAYREQASKIRIMAMPVSGLSGTLVILMATVDSRYPIEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQE
YSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFVISTPLPAGEEGKVIEWHYVRERSEEEWASL
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVE
VLFTQGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIR
VRIISDKGNAKGNTATSDAN
>Mature_660_residues
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGKIKALPGQAANHLVNEGMKSA
FPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQLGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDA
DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRN
YDIVMAYREQASKIRIMAMPVSGLSGTLVILMATVDSRYPIEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQE
YSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFVISTPLPAGEEGKVIEWHYVRERSEEEWASL
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVE
VLFTQGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIR
VRIISDKGNAKGNTATSDAN

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=270, Percent_Identity=35.1851851851852, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI145693120, Length=376, Percent_Identity=30.0531914893617, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 72777; Mature: 72777

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGK
CCCCCCCHHHHEEEEEEECCCCEEEEECCCHHHHHHHHCCCHHCCCHHHCCCHHHHHCCC
IKALPGQAANHLVNEGMKSAFPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQ
EEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHC
LGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDADIRYSHLRGGIGGEVYKDSL
CCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEEHHHCCCCCEEHHHCCCCCCCEECCCE
AFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
EECCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEHHHHCCCEEEE
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLD
EECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHCC
YRNVGAPSNTTNRRAFVDRNYDIVMAYREQASKIRIMAMPVSGLSGTLVILMATVDSRYP
CCCCCCCCCCCCCEEEEECCCEEEEEEECCCCEEEEEEEECCCCCCEEEEEEEECCCCCC
IEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQEYSLYLTVTDSRGTRVTSERI
CEEEECCCCHHEEEEEEEECCCCCCEEECCCCEEECCCCEEEEEEEEECCCCCEEECCCC
PVRVTQDETSFRSWINVINDDVQVEDGNFVISTPLPAGEEGKVIEWHYVRERSEEEWASL
CEEEECCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCEEEEEEHHCCCHHHHHCC
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVK
CCCEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCC
GTVLLQAQSDSIAQKVTSVEVLFTQGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFN
EEEEEEECCCHHHHHHCEEEEEEECCCCCCCCCEEECEECCCCEEEEEEECCCCCCCCCC
YQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIRVRIISDKGNAKGNTATSDAN
EEEEECHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGK
CCCCCCCHHHHEEEEEEECCCCEEEEECCCHHHHHHHHCCCHHCCCHHHCCCHHHHHCCC
IKALPGQAANHLVNEGMKSAFPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQ
EEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHC
LGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDADIRYSHLRGGIGGEVYKDSL
CCCCCCCCCCCCCEEEEEECCCCEECCCEEEEEEHHHCCCCCEEHHHCCCCCCCEECCCE
AFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
EECCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEHHHHCCCEEEE
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLD
EECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHCC
YRNVGAPSNTTNRRAFVDRNYDIVMAYREQASKIRIMAMPVSGLSGTLVILMATVDSRYP
CCCCCCCCCCCCCEEEEECCCEEEEEEECCCCEEEEEEEECCCCCCEEEEEEEECCCCCC
IEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQEYSLYLTVTDSRGTRVTSERI
CEEEECCCCHHEEEEEEEECCCCCCEEECCCCEEECCCCEEEEEEEEECCCCCEEECCCC
PVRVTQDETSFRSWINVINDDVQVEDGNFVISTPLPAGEEGKVIEWHYVRERSEEEWASL
CEEEECCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCEEEEEEHHCCCHHHHHCC
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVK
CCCEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCC
GTVLLQAQSDSIAQKVTSVEVLFTQGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFN
EEEEEEECCCHHHHHHCEEEEEEECCCCCCCCCEEECEECCCCEEEEEEECCCCCCCCCC
YQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIRVRIISDKGNAKGNTATSDAN
EEEEECHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]