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The map label for this gene is mdtI

Identifier: 29141856

GI number: 29141856

Start: 1448322

End: 1448651

Strand: Direct

Name: mdtI

Synonym: t1403

Alternate gene names: 29141856

Gene position: 1448322-1448651 (Clockwise)

Preceding gene: 29141855

Following gene: 29141859

Centisome position: 30.22

GC content: 55.45

Gene sequence:

>330_bases
GTGCAACAATTTGAATGGATACACGGCGCCTGGCTTGGGCTGGCAATAATGCTGGAAATCGCGGCTAACGTTCTGTTGAA
ATTTTCGGACGGCTTTCGCCGTAAATGCTATGGCATCTTATCGCTTGCCGCTGTTCTGGCCGCCTTCAGCGCGCTTTCCC
AGGCGGTAAAAGGGATAGACCTGTCGGTGGCGTATGCGCTATGGGGCGGTTTTGGTATTGCCGCCACGCTGGCGGCGGGC
TGGGTGCTCTTCGGCCAGCGCTTAAATCCCAAAGGCTGGGTTGGCGTGATATTGCTGCTCGCCGGAATGGTCATGATAAA
ATTTGCCTGA

Upstream 100 bases:

>100_bases
TCAACCATGAAGATTGCCGGCTTGCTGACGCTGGTCGCCGGCATCGTATTGATCAAATCAGGGACGCGTAAACCCGGCAA
ACCGGTGAAGGAGGCGACTC

Downstream 100 bases:

>100_bases
GACGATCGCTGCCGGTCAGGCAGCGATTCCCGCATTAATCCTGCGCCAGAGCTTTCAGCTTATCGCGAAAGCCGGTGACG
GATATAGCGCGGTTATCGGC

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAG
WVLFGQRLNPKGWVGVILLLAGMVMIKFA

Sequences:

>Translated_109_residues
MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAG
WVLFGQRLNPKGWVGVILLLAGMVMIKFA
>Mature_109_residues
MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAG
WVLFGQRLNPKGWVGVILLLAGMVMIKFA

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=83.4862385321101, Blast_Score=166, Evalue=4e-43,
Organism=Escherichia coli, GI1786755, Length=98, Percent_Identity=35.7142857142857, Blast_Score=62, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTI_SALA4 (B5F6G3)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002146561.1
- ProteinModelPortal:   B5F6G3
- GeneID:   6796428
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B1690
- HOGENOM:   HBG740972
- OMA:   AGWIMFN
- ProtClustDB:   PRK10650
- GO:   GO:0006810
- HAMAP:   MF_01597
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 11686; Mature: 11686

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe4f39a8)-; HASH(0xb7e1b4c)-; HASH(0xe7974e0)-; HASH(0xda4ce60)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA