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The map label for this gene is ccmC [H]

Identifier: 29141126

GI number: 29141126

Start: 695425

End: 696162

Strand: Direct

Name: ccmC [H]

Synonym: t0612

Alternate gene names: 29141126

Gene position: 695425-696162 (Clockwise)

Preceding gene: 29141125

Following gene: 29141127

Centisome position: 14.51

GC content: 65.18

Gene sequence:

>738_bases
ATGTGGAAAACCCTTCATCAGCTGGCGGCGCCGCCCCGGCTGTATCAGATTTGCGGCAGGCTTGTGCCGTGGCTGGCGGC
AGCCGGCATCATTGTGCTGGCCACGGGCTGGGTCCGGGGCTTTGGTTTCGCCCCGGCGGACTACCAGCAGGGGGAGAGCT
ACCGCATTATGTACCTGCATGTCCCGGCGGCCATCTGGTCGATGGGTATCTATGCGGCGATGGCGGTGGCGGCGTTCACC
GGGCTGGTCTGGCAGATGAAAATGGCCAGCCTTGCCGTCGCGGCGATGGCGCCGGTGGGGGCGGTGTACACCTTCATCGC
GCTGGTCACCGGCGCGGCGTGGGGCAAACCGATGTGGGGCACCTGGTGGGTGTGGGACGCGCGCCTGACCTCGGAGCTGG
TGCTGCTGTTTCTCTATGCCGGGGTCATCGCCCTGTGGCACGCCTTTGACGACCGTAAAATGGCCGGGCGCGCGGCGGGC
ATTCTGGTGCTGGTCGGCGTGGTGAACCTGCCGGTTATCCACTATTCCGTCGAGTGGTGGAACACCCTGCACCAGGGCTC
GACGCGGATGCAGCTGAGTATCGACCCGGCGATGCGCTCGCCGCTGCGCTGGGCCATCGCCGGCTTCCTGCTGCTCTTTA
TGACGCTGGCGCTGATGCGGATGCGCAACCTGATTTTACTGATGGAAAAACGCCGCCCGTGGGTGAGCGAACTGATACTG
AAAAGGGGGCACCGGTGA

Upstream 100 bases:

>100_bases
GTTAAGCCCGTTCGCCACCGCGGCGGCGCTGCGCATCAGTACGCAGTAGCGCCCCGGCACGACGGACATTTTACTGGTTT
CAGGAGGTCAGGTGACGACT

Downstream 100 bases:

>100_bases
GTCCGGCATTTTCATCGTGGAGCGATTTTTTCGCCATGGGCGGGTACGCCTTTTTTGTCTGGCTGGCGGTGGCGATGACC
GTGGCGCCGCTGGCGCTGCT

Product: heme exporter protein C1

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGESYRIMYLHVPAAIWSMGIYAAMAVAAFT
GLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLALMRMRNLILLMEKRRPWVSELIL
KRGHR

Sequences:

>Translated_245_residues
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGESYRIMYLHVPAAIWSMGIYAAMAVAAFT
GLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLALMRMRNLILLMEKRRPWVSELIL
KRGHR
>Mature_245_residues
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGESYRIMYLHVPAAIWSMGIYAAMAVAAFT
GLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLALMRMRNLILLMEKRRPWVSELIL
KRGHR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=245, Percent_Identity=86.530612244898, Blast_Score=435, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 27539; Mature: 27539

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGESYRIMYLH
CCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
VPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAGILVLVGVVNLPVIHYSVEWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEEHHHH
NTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLALMRMRNLILLMEKRRPWVSELIL
HHHHCCCCEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KRGHR
HCCCC
>Mature Secondary Structure
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGESYRIMYLH
CCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
VPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAGILVLVGVVNLPVIHYSVEWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEEHHHH
NTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLALMRMRNLILLMEKRRPWVSELIL
HHHHCCCCEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KRGHR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]