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The map label for this gene is pmrD [H]

Identifier: 29141074

GI number: 29141074

Start: 635546

End: 635803

Strand: Direct

Name: pmrD [H]

Synonym: t0559

Alternate gene names: 29141074

Gene position: 635546-635803 (Clockwise)

Preceding gene: 29141073

Following gene: 29141082

Centisome position: 13.26

GC content: 47.67

Gene sequence:

>258_bases
ATGGAATGGTTGGTTAAGAAATCGCATTATGTCAAAAAGAGGGCGTGCCATGTTCTGGTGCTGTGCGATAGCGGCGGTTC
GCTAAAAATGATCGCCGAGGCGAATTCCATGATATTACTGAGTCCCGGCGATATCCTGTCGCCTTTACAGGATGCGCAGT
ATTGTATTAATCGGGAAAAACACCAGACCTTAAAAATCGTTGATGCACGCTGTTATTCCTGCGACGAATGGCAGCGGTTG
ACGCGCAAGCCATTATGA

Upstream 100 bases:

>100_bases
TAATGTTAGGTTAATATACAACCATTCCATCGCTATTGCCGTTTTGTTTATCCGTTGATGTGTAACGTGTTATGAACAAT
CAGCGTGAAACGGGGGCGCT

Downstream 100 bases:

>100_bases
TCTGGCGGGCAGAAAAATCAGCATTACCCCCGCCATAATGCACAATACGCCGAGCATCGCTTTTAGGCTGAAAGCGCCTT
GCAAACCGGGTAACAACATT

Product: polymyxin B resistance protein

Products: NA

Alternate protein names: BasR post-transcriptional activator; Polymyxin resistance protein pmrD [H]

Number of amino acids: Translated: 85; Mature: 85

Protein sequence:

>85_residues
MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGDILSPLQDAQYCINREKHQTLKIVDARCYSCDEWQRL
TRKPL

Sequences:

>Translated_85_residues
MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGDILSPLQDAQYCINREKHQTLKIVDARCYSCDEWQRL
TRKPL
>Mature_85_residues
MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGDILSPLQDAQYCINREKHQTLKIVDARCYSCDEWQRL
TRKPL

Specific function: Interacts with phosphorylated BasR protein to mediate transcriptional induction of BasR-activated genes to induce polymyxin resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pmrD family [H]

Homologues:

Organism=Escherichia coli, GI87082076, Length=79, Percent_Identity=59.4936708860759, Blast_Score=96, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020146
- ProDom:   PD028730 [H]

Pfam domain/function: PF11183 PmrD [H]

EC number: NA

Molecular weight: Translated: 9776; Mature: 9776

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
5.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
9.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGDILSPLQDAQYCINREK
CCCCCCCHHHHHHCCCEEEEEECCCCCEEEEECCCCEEEECCCHHCCHHHHHHHHHCCCC
HQTLKIVDARCYSCDEWQRLTRKPL
CCEEEEEECCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGDILSPLQDAQYCINREK
CCCCCCCHHHHHHCCCEEEEEECCCCCEEEEECCCCEEEECCCHHCCHHHHHHHHHCCCC
HQTLKIVDARCYSCDEWQRLTRKPL
CCEEEEEECCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8206837; 11677609; 9570402 [H]