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The map label for this gene is menC [H]

Identifier: 29141072

GI number: 29141072

Start: 633122

End: 634084

Strand: Direct

Name: menC [H]

Synonym: t0557

Alternate gene names: 29141072

Gene position: 633122-634084 (Clockwise)

Preceding gene: 29141071

Following gene: 29141073

Centisome position: 13.21

GC content: 60.33

Gene sequence:

>963_bases
ATGCGTAGCGCGCAGGTATACCGCTGGCAGATCCCCATGGACGCGGGGGTGGTTCTGCGCGACAGGCGGTTAAAAACTCG
CGACGGGCTGTATGTTTGTCTGCGTGACGGCGAGCGTGAAGGGTGGGGAGAGATCTCCCCGCTGCCGGGCTTCAGTCAGG
AAACGTGGGAAGAGGCGCAGACGGCGCTCCTGACATGGGTGAATGACTGGCTTCAGGGGAGCGAGGGATTACCGGAGATG
CCTTCGGTCGCGTTTGGCGCAAGCTGCGCGCTGGCGGAACTGACTGGCGTCTTGCCGGAGGCGGCGGACTATCGCGCCGC
GCCGTTATGCACTGGCGATCCTGACGATTTGGTACTGCGGCTTGCCGATATGCCCGGCGAGAAAATCGCTAAGGTCAAAG
TGGGTCTCTATGAAGCGGTACGCGACGGCATGGTGGTTAATTTGCTGCTGGAGGCGATCCCGGATCTGCATCTGCGTCTG
GATGCGAATCGCGCCTGGACGCCGCTAAAAGCCCAACAGTTCGCAAAGTATGTTAATCCGGATTACCGCGCTCGTATCGC
CTTTCTCGAAGAACCGTGTAAGACGCGGGATGATTCCCGCGCCTTTGCCCGTGAAACCGGCATCGCGATTGCCTGGGACG
AAAGTCTGCGCGAAGCGGATTTCACCTTTGAAGCCGAAGAGGGCGTCAGGGCTGTGGTTATCAAACCTACGCTGACCGGA
TCGCTTGATAAAGTGCGTGAGCAAGTCGCTGCCGCCCATGCGTTGGGACTGACGGCGGTCATCAGCTCTTCGATCGAGTC
CAGCCTCGGCCTGACGCAACTGGCGCGGATTGCCGCCTGGTTGACGCCGGGAACGCTGCCCGGACTGGATACCTTGCATC
TGATGCAGGCGCAACAGGTTCGCCCCTGGCCTGGTAACGCGTTGCCTTGTCTGAAGCGTGATGAGCTGGAACGACTGTTA
TGA

Upstream 100 bases:

>100_bases
CTACCATGCTGTTCTACATGACGGAAGAAGGGCAGGAAGGCCGTAACGCCTTTAACCAGAAGCGTCAGCCTGACTTCAGC
AAATTCAAACGGAACCCATA

Downstream 100 bases:

>100_bases
CATTCACGGACTGGCCGTGGCGCCACTGGCGTCAGGTTCGCAGTCAGGCGCCCGCTCTGCGCCTGAACGATGAAGTGCTA
AGCTGGCGCGCCCTCTGTGA

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGEISPLPGFSQETWEEAQTALLTWVNDWLQGSEGLPEM
PSVAFGASCALAELTGVLPEAADYRAAPLCTGDPDDLVLRLADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
DANRAWTPLKAQQFAKYVNPDYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLREADFTFEAEEGVRAVVIKPTLTG
SLDKVREQVAAAHALGLTAVISSSIESSLGLTQLARIAAWLTPGTLPGLDTLHLMQAQQVRPWPGNALPCLKRDELERLL

Sequences:

>Translated_320_residues
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGEISPLPGFSQETWEEAQTALLTWVNDWLQGSEGLPEM
PSVAFGASCALAELTGVLPEAADYRAAPLCTGDPDDLVLRLADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
DANRAWTPLKAQQFAKYVNPDYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLREADFTFEAEEGVRAVVIKPTLTG
SLDKVREQVAAAHALGLTAVISSSIESSLGLTQLARIAAWLTPGTLPGLDTLHLMQAQQVRPWPGNALPCLKRDELERLL
>Mature_320_residues
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGEISPLPGFSQETWEEAQTALLTWVNDWLQGSEGLPEM
PSVAFGASCALAELTGVLPEAADYRAAPLCTGDPDDLVLRLADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
DANRAWTPLKAQQFAKYVNPDYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLREADFTFEAEEGVRAVVIKPTLTG
SLDKVREQVAAAHALGLTAVISSSIESSLGLTQLARIAAWLTPGTLPGLDTLHLMQAQQVRPWPGNALPCLKRDELERLL

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=320, Percent_Identity=88.4375, Blast_Score=574, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35360; Mature: 35360

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGEISPLPGFSQETWEEAQ
CCCCCEEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
TALLTWVNDWLQGSEGLPEMPSVAFGASCALAELTGVLPEAADYRAAPLCTGDPDDLVLR
HHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEE
LADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKAQQFAKYVNP
ECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCC
DYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLREADFTFEAEEGVRAVVIKPTLTG
CHHEEHHHHHCCCCCCCHHHHHHHHCCEEEEECCHHHHCCCEEECCCCCEEEEECCCCCC
SLDKVREQVAAAHALGLTAVISSSIESSLGLTQLARIAAWLTPGTLPGLDTLHLMQAQQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
RPWPGNALPCLKRDELERLL
CCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGEISPLPGFSQETWEEAQ
CCCCCEEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
TALLTWVNDWLQGSEGLPEMPSVAFGASCALAELTGVLPEAADYRAAPLCTGDPDDLVLR
HHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEE
LADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKAQQFAKYVNP
ECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCC
DYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLREADFTFEAEEGVRAVVIKPTLTG
CHHEEHHHHHCCCCCCCHHHHHHHHCCEEEEECCHHHHCCCEEECCCCCEEEEECCCCCC
SLDKVREQVAAAHALGLTAVISSSIESSLGLTQLARIAAWLTPGTLPGLDTLHLMQAQQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
RPWPGNALPCLKRDELERLL
CCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA