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The map label for this gene is nuoA

Identifier: 29141051

GI number: 29141051

Start: 610189

End: 610632

Strand: Direct

Name: nuoA

Synonym: t0536

Alternate gene names: 29141051

Gene position: 610189-610632 (Clockwise)

Preceding gene: 29141050

Following gene: 29141052

Centisome position: 12.73

GC content: 52.93

Gene sequence:

>444_bases
ATGAGTATGTCAACATCCACTGAAGTCATCGCTCATCACTGGGCATTCGCTATCTTTCTTATCGTTGCCATTGGCCTGTG
CTGCCTGATGCTGGTAGGCGGTTGGTTTTTGGGCGGTCGCGCACGCGCGAGGCACAAGAACGTTCCGTTTGAATCAGGTA
TCGACTCGGTCGGCACCGCCCGCTTACGCTTGTCTGCCAAGTTTTACCTGGTAGCCATGTTCTTCGTTATCTTCGACGTT
GAAGCGCTGTATCTGTTCGCATGGTCAACTTCTATCCGCGAAAGCGGCTGGGTTGGCTTTGTGGAAGCTGCAATTTTTAT
TTTTGTGTTACTGGCTGGTCTGGTTTATCTGGCGCGTATTGGCGCGTTGGACTGGACGCCCGCGCGTTCACGCCGCGAGC
GTATGAACCCGGAAACGAACAGTATCGCTAATCGTCAACGCTAA

Upstream 100 bases:

>100_bases
TACAGTAATTGTAGGGTTTTTTTATTCCTCCCCTGAATCGATGTGGCGTCCATCTGCCGTAAAGAGCAGAGGAACTGGCG
CTACTTTTGATGAGTAAGCA

Downstream 100 bases:

>100_bases
CCGCGAGGCATTAAGATGGATTATACGCTCACCCGCATAGATCCTAACGGTGAGAATGACCGTTACCCCCTGCAAAAACA
GGAGATCGTAACCGACCCCC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDV
EALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR

Sequences:

>Translated_147_residues
MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDV
EALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR
>Mature_146_residues
SMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVE
ALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=147, Percent_Identity=97.9591836734694, Blast_Score=291, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_SALA4 (B5EZK9)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002147286.1
- PRIDE:   B5EZK9
- GeneID:   6795244
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B2467
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- ProtClustDB:   PRK06602
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 16494; Mature: 16362

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc428e88)-; HASH(0xd142fac)-; HASH(0xc0bfcb4)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHCCCCCCCHH
RLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GALDWTPARSRRERMNPETNSIANRQR
CCCCCCCCHHHHHHCCCCHHHHCCCCH
>Mature Secondary Structure 
SMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHCCCCCCCHH
RLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GALDWTPARSRRERMNPETNSIANRQR
CCCCCCCCHHHHHHCCCCHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA