Click here to switch to the map view.

The map label for this gene is apaH [H]

Identifier: 29140633

GI number: 29140633

Start: 101219

End: 102067

Strand: Reverse

Name: apaH [H]

Synonym: t0091

Alternate gene names: 29140633

Gene position: 102067-101219 (Counterclockwise)

Preceding gene: 29140634

Following gene: 29140625

Centisome position: 2.13

GC content: 55.48

Gene sequence:

>849_bases
ATGGCAACTTATCTCATCGGCGACGTTCACGGTTGCTACGACGAACTGATCGCCTTATTACAGCAAGTGGAATTTACGCC
AGATACAGACACTCTATGGCTGACTGGCGATTTGGTCGCCCGCGGTCCCGGTTCGCTGGACGTGTTACGCTACGTCAAAT
CGCTTGGCAATAGCGTGCGTTTGGTGCTGGGGAATCACGATTTACACCTGTTGGCCGTATTCGCCGGGATTAGCCGCAAC
AAACCTAAAGACCGGCTGACCCCGCTTCTTGAAGCGCCGGACGCCGATGAGCTGTTGAATTGGTTACGCCGTCAGCCGCT
GTTGCAGGTAGATGAAGAGAAAAAGCTGGTCATGGCGCATGCGGGTATTACCCCACAGTGGGATTTGCAGACGGCAAAAG
AGTGCGCCCGCGATGTTGAAGCGGTGCTGTCGAGCGACTCGTACCCGTTTTTCCTCGACGCGATGTATGGCGATATGCCG
AATAACTGGTCGCCGGAGTTAAGCGGTCTGGCGCGGCTACGCTTTATTACTAATGCCTTTACCCGTATGCGTTACTGCTT
TCCTAACGGTCAACTGGATATGTACAGCAAAGCGTCGCCGGAAAATGCCCCTGCGCCGCTGAAGCCGTGGTTCGCCATTC
CGGGACCGGTGAGCGAGGCTTACAGTATTGCTTTCGGGCACTGGGCGTCGCTGGAAGGGAAAGGGACGCCAGAAGGTATT
TACGCGCTGGATACCGGCTGCTGCTGGGGCGGGGAGTTAACCTGTTTACGTTGGGAAGATAAACAGTATTTTGTGCAGCC
GTCAAACCGCCAGATGGATATGGGCGAAGGCGAAGCGGTCAACGCCTGA

Upstream 100 bases:

>100_bases
GGTCATTACGAAATGATCGATGAAAATGGCGACGCCTTTACCATCGACATTCCCGTGTTTCGACTCGCCGTCCCTACACT
CATTCACTAAAATTATAACA

Downstream 100 bases:

>100_bases
TAGGTTTATGCCTGATGGCGCTACGCTTATCAGGCCTACATCCGGCTCAAGAGTAGGCCGGATAAGGCATTTCGCCGCCA
TCCGGCACTACAGCGTTAAC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRN
KPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
NNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGI
YALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA

Sequences:

>Translated_282_residues
MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRN
KPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
NNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGI
YALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
>Mature_281_residues
ATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNK
PKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPN
NWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGIY
ALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=279, Percent_Identity=93.1899641577061, Blast_Score=545, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31431; Mature: 31300

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVR
CCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAH
EEECCCCCEEHHEEHHCCCCCCHHHHCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEEE
AGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHH
TRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGI
HHHEEECCCCCEECCCCCCCCCCCCCCCCCEECCCCHHHHHEEHHCCEECCCCCCCCCCE
YALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
EEEECCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVR
CEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAH
EEECCCCCEEHHEEHHCCCCCCHHHHCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEEE
AGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHH
TRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGI
HHHEEECCCCCEECCCCCCCCCCCCCCCCCEECCCCHHHHHEEHHCCEECCCCCCCCCCE
YALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
EEEECCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA