Click here to switch to the map view.

The map label for this gene is citE [H]

Identifier: 29140604

GI number: 29140604

Start: 69996

End: 70865

Strand: Direct

Name: citE [H]

Synonym: t0062

Alternate gene names: 29140604

Gene position: 69996-70865 (Clockwise)

Preceding gene: 29140603

Following gene: 29140605

Centisome position: 1.46

GC content: 55.4

Gene sequence:

>870_bases
ATGAGACCTCGTCGCAGTATGTTGTTTATCCCCGGCGCAAATGCGGCCATGTTGAGCACCTCGTTTGTCTATGGTGCGGA
CGCGGTGATGTTCGACTTAGAAGACGCCGTAGCATTACGTGAGAAAGATACCGCCCGTCTTTTAGTCCATCACGCGCTTC
AACATCCGTTCTATCAGGATGTTGAAAAAGTGGTGCGCATTAATCCACTGAACACGCCATTCGGTCTGGCCGATCTTGAG
GCCGTCGTGCGTGGTGGCGCGGATATCGTGCGTCTGCCGAAAACCGACAGCAAAAACGATGTGCTGGAGCTGGAAGCGCA
GGTTGAACGGATCGAACGTGAATGTGGACGTGAAGTCGGCAGTACCAGGCTGATGGCGGCGATCGAATCAGCGAAAGGCG
TGGTCAATGCCGTCGACATCGCCACCTCCAGCCCGCGCATGGTGGCAATTGCGCTGGCGGCATTTGATTACGTGATGGAT
ATGGGCACCAGCCGGGGCGATGGCACCGAGCTGTTCTACGCCCGCTGCGCAGTGCTGCATGCGGCGCGCGTTGCGGGTAT
TGCCGCCTATGATGTCGTTTGGTCGGATATCAATAATGAAGAAGGCTTCCTGAAGGAAGTGCAGTTGGCGAAAGGGCTTG
GTTTTAACGGTAAGTCCTTAGTGAATCCACGTCAGATTGAGCTGTTACATCAGGCTTATTCTCCGACGCGTAAAGAAGTT
GAGCATGCGCACGAGGTGATTGCCGCCGCTGAAGAGGCTGAGTCTCGCGGTCTGGGCGTCGTTTCACTCAACGGCAAAAT
GATTGACGGCCCGATTATCGACCACGCGCGCAAAGTGGTGGCGCTGTCGGCTTCCGGTATTCGTGATTAA

Upstream 100 bases:

>100_bases
GCGTCGATGACAAAGGCGCGCTGGAGTGTATTTTACGCGCCCGAGTGCAGGCGGCGGCGTTACGCGCTGCAGAACAAACG
GAAATTCAATGGAGTGCGTT

Downstream 100 bases:

>100_bases
GGAAGGAACCATGAAAGAGACTGTAACTATGCTCAATCAGCAATATGTCGTACCGGAAGGATTACAACCCTACCAGGGGG
TAACAGTGAATAGCCCGTGG

Product: citrate lyase subunit beta

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDTARLLVHHALQHPFYQDVEKVVRINPLNTPFGLADLE
AVVRGGADIVRLPKTDSKNDVLELEAQVERIERECGREVGSTRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMD
MGTSRGDGTELFYARCAVLHAARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGKSLVNPRQIELLHQAYSPTRKEV
EHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHARKVVALSASGIRD

Sequences:

>Translated_289_residues
MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDTARLLVHHALQHPFYQDVEKVVRINPLNTPFGLADLE
AVVRGGADIVRLPKTDSKNDVLELEAQVERIERECGREVGSTRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMD
MGTSRGDGTELFYARCAVLHAARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGKSLVNPRQIELLHQAYSPTRKEV
EHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHARKVVALSASGIRD
>Mature_289_residues
MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDTARLLVHHALQHPFYQDVEKVVRINPLNTPFGLADLE
AVVRGGADIVRLPKTDSKNDVLELEAQVERIERECGREVGSTRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMD
MGTSRGDGTELFYARCAVLHAARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGKSLVNPRQIELLHQAYSPTRKEV
EHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHARKVVALSASGIRD

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=295, Percent_Identity=26.4406779661017, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI87081764, Length=290, Percent_Identity=63.448275862069, Blast_Score=367, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17557458, Length=299, Percent_Identity=28.4280936454849, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 31362; Mature: 31362

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDTARLLVHHALQHPFYQD
CCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHCCHHHH
VEKVVRINPLNTPFGLADLEAVVRGGADIVRLPKTDSKNDVLELEAQVERIERECGREVG
HHHHHEECCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
STRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMDMGTSRGDGTELFYARCAVLH
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGKSLVNPRQIELLHQAYSPTRKEV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHH
EHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHARKVVALSASGIRD
HHHHHHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHEEEEECCCCCC
>Mature Secondary Structure
MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDTARLLVHHALQHPFYQD
CCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHCCHHHH
VEKVVRINPLNTPFGLADLEAVVRGGADIVRLPKTDSKNDVLELEAQVERIERECGREVG
HHHHHEECCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
STRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMDMGTSRGDGTELFYARCAVLH
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGKSLVNPRQIELLHQAYSPTRKEV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHH
EHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHARKVVALSASGIRD
HHHHHHHHHHHHHHHCCCEEEEECCEEECCHHHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2205500; 7830578 [H]