Click here to switch to the map view.

The map label for this gene is citC [H]

Identifier: 29140602

GI number: 29140602

Start: 68633

End: 69676

Strand: Direct

Name: citC [H]

Synonym: t0060

Alternate gene names: 29140602

Gene position: 68633-69676 (Clockwise)

Preceding gene: 29140595

Following gene: 29140603

Centisome position: 1.43

GC content: 53.54

Gene sequence:

>1044_bases
ATGCAGAATAGAGTGAATCTAATATTTAAACGCATTTATTTGCAAAAGGATGTATTGCGTCGCGAGTCGGTCGCCATGTT
TCTGGAGGGCGTGGGACTCGCCCTGGAAGATGATTGTGAAATCGCGGTATGCGCATATTGGCAGGGTGAGATAGTTGGAT
GCGGCTCGCTGGCCGGAAACGTACTGAAATGCATCGCCGTTTCCCCGGTTTTACAAGGGGAAGGGCTCAGCCTCAAACTG
CTGACTGAGCTGCTTACATTGGCCTACGAGTTAAACCGCAGCGAGCTTTTCCTGTTCACTAAGCCGCAAAATCGGTTGCT
GTTTTCTGGCGCGGGGTTTTGGCCCATTGCGCAGGCAGGTGAGCTGGCGGTGTTAATGGAGAACAGCAGTGAACGGTTAG
CGCGCTTTTGTCGCCAACTGGCGCTTTATCGTCAACCGGGAAAAACGATCGGCGCCATTGTCATGAACGCCAATCCGTTT
ACCTTGGGCCACCGTTATCTGGTGGAGCAAGCGGCTGCGGCCTGTGACTGGTTGCATCTGTTTGTAGTCAAAGAAGATGC
TTCATTTTTTTCCTATACCGACCGTTGGGCGCTGATCGAACAAGGAATCGCGGGCATTGACAACGTCACGTTGCATTCCG
GCTCCGCTTATATGATCTCGCGTGCGACGTTTCCCGGCTATTTCCTCAAAGAAAAAGGGGTTGTGGACGACTGCCATTGC
CAGATCGATCTGCAACTCTTCCGTGAACATCTGGCTCCAGCGCTGGGGATTACCCATCGTTTTGTCGGCAGTGAGCCGTT
TTGTCCTCTGACCTGTGCCTATAACCAGCGGATGCACGACATTTTACACGATCCGAAGCGCAGCGGCCCGGTTATTGAGG
TCGTCGAGCTGGCGCGGGTGGAGAAAAACGGCACGGCTATTTCCGCCTCTCGCGTCAGAAAACTGTATAGCGAACGTAAT
TGGCCGGCAATAAGCGCGCTGGTGCCTGCTGGCACCCTGGCATATCTGCAGCGGCATGCCGCCAGACACACTGAAACCAT
ATGA

Upstream 100 bases:

>100_bases
AAAAACCATAAAGCTTATAAAAGCAAGGGGGAAAGTGTGATGTCTATTCCAGACGAGTAATACAAACGCTGGCGAAATAT
GCAACGTTATTTGCTGACGG

Downstream 100 bases:

>100_bases
CGTAACACCGTTAACAAGGAACATAACTAATGAAAATCATTAAAGATGCCCTGGCAGGCACGCTGGAATCCAGCGATGTG
ATGATCAGGATTGGTCCATC

Product: [citrate (Pro-3S)-lyase] ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGNVLKCIAVSPVLQGEGLSLKL
LTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERN
WPAISALVPAGTLAYLQRHAARHTETI

Sequences:

>Translated_347_residues
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGNVLKCIAVSPVLQGEGLSLKL
LTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERN
WPAISALVPAGTLAYLQRHAARHTETI
>Mature_347_residues
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGNVLKCIAVSPVLQGEGLSLKL
LTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERN
WPAISALVPAGTLAYLQRHAARHTETI

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=332, Percent_Identity=49.6987951807229, Blast_Score=340, Evalue=8e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 38702; Mature: 38702

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCEEECHHHHHH
VLKCIAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAG
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCC
ELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGHRYLVEQAAAACDWLHL
CEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEE
FVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
EEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCEEEECCCCCCCCEE
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARV
EEEHHHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EKNGTAISASRVRKLYSERNWPAISALVPAGTLAYLQRHAARHTETI
CCCCCEECHHHHHHHHHCCCCCEEEHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCEEECHHHHHH
VLKCIAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAG
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCC
ELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGHRYLVEQAAAACDWLHL
CEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEE
FVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
EEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCEEEECCCCCCCCEE
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARV
EEEHHHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EKNGTAISASRVRKLYSERNWPAISALVPAGTLAYLQRHAARHTETI
CCCCCEECHHHHHHHHHCCCCCEEEHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7830578 [H]