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The map label for this gene is dcd

Identifier: 28572937

GI number: 28572937

Start: 902676

End: 903266

Strand: Reverse

Name: dcd

Synonym: TW796

Alternate gene names: 28572937

Gene position: 903266-902676 (Counterclockwise)

Preceding gene: 28572938

Following gene: 28572936

Centisome position: 97.55

GC content: 48.39

Gene sequence:

>591_bases
ATGCTACTGTCAGATGTTGACATACAAGCCGCACTGGAAGACAAGCTGATACAGATCGATCCATTCGATCCCCAGATGTT
GCAACCGGCCAGCTTAGATATCAGACTCAGTAGGTATTTTAGGCTTTTCAATAATCACACGTATGCCTATATAGACCCGG
CAGAGCCACAAGAAGCGCTAACGCGTCTTGTGGAAGTTGCCGAGAATCAGGCGTTCGTGCTGCACCCAGGCGAGTTTATT
CTTGGCTCAACCTGTGAAACGGTATCTCTTTCAAATGATCTGGCCGCGCGATTGGAAGGCAAAAGCTCCCTTGGCAGGCT
CGGTTTACTAACACATTCTACGGCCGGCTTTATAGATCCCGGATTTTCGGGGCAGATTACGCTCGAGCTTGGTAATGTTG
CGACTTTACCCATAAAACTGTGGCCAGGAATGAAGATTGGCCAATTGTGTTTTTTTCAGTTATCTTCACCGGCAAAAAAT
GCTTACGGTTCGCCCGTATGTGCCTCTAGGTACCAGGGACAGCGCGGCCCAACCGCGAGTCTTTCGCATCAGCATTTTTA
TCGCGCACGTTTTACAGAAATAGGATTATGA

Upstream 100 bases:

>100_bases
AGCGAGTGACGGGAATCGAACCCGCGCCGTCAGCTTGGGAAGCTGAAGTTCTGCCATTGAACTACACTCGCACGTGGCAT
AAATTCTACCGGAGGGCAAA

Downstream 100 bases:

>100_bases
GCATTATTAGATCTGAGCGATATTCGGCAATTTTTCTTCTTTGCTCGGCAGCGCTAGCAATTATATTTGCTAATGTTCTT
GACCCGGACACATGGCATGC

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAYIDPAEPQEALTRLVEVAENQAFVLHPGEFI
LGSTCETVSLSNDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGQITLELGNVATLPIKLWPGMKIGQLCFFQLSSPAKN
AYGSPVCASRYQGQRGPTASLSHQHFYRARFTEIGL

Sequences:

>Translated_196_residues
MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAYIDPAEPQEALTRLVEVAENQAFVLHPGEFI
LGSTCETVSLSNDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGQITLELGNVATLPIKLWPGMKIGQLCFFQLSSPAKN
AYGSPVCASRYQGQRGPTASLSHQHFYRARFTEIGL
>Mature_196_residues
MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAYIDPAEPQEALTRLVEVAENQAFVLHPGEFI
LGSTCETVSLSNDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGQITLELGNVATLPIKLWPGMKIGQLCFFQLSSPAKN
AYGSPVCASRYQGQRGPTASLSHQHFYRARFTEIGL

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=189, Percent_Identity=44.4444444444444, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_TROW8 (Q83H71)

Other databases:

- EMBL:   BX251412
- RefSeq:   NP_789717.1
- ProteinModelPortal:   Q83H71
- SMR:   Q83H71
- STRING:   Q83H71
- GeneID:   1064996
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW796
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- PhylomeDB:   Q83H71
- ProtClustDB:   PRK00416
- BioCyc:   TWHI218496:TW0762-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 21571; Mature: 21571

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAYIDPAEPQEAL
CCCCCCCHHHHHCCCEEEECCCCCHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCHHHHH
TRLVEVAENQAFVLHPGEFILGSTCETVSLSNDLAARLEGKSSLGRLGLLTHSTAGFIDP
HHHHHHHCCCEEEEECCCEEECCCCCEEECCCHHHHHCCCCCCCCEEEEEEECCCCCCCC
GFSGQITLELGNVATLPIKLWPGMKIGQLCFFQLSSPAKNAYGSPVCASRYQGQRGPTAS
CCCCEEEEEECCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCC
LSHQHFYRARFTEIGL
CCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAYIDPAEPQEAL
CCCCCCCHHHHHCCCEEEECCCCCHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCHHHHH
TRLVEVAENQAFVLHPGEFILGSTCETVSLSNDLAARLEGKSSLGRLGLLTHSTAGFIDP
HHHHHHHCCCEEEEECCCEEECCCCCEEECCCHHHHHCCCCCCCCEEEEEEECCCCCCCC
GFSGQITLELGNVATLPIKLWPGMKIGQLCFFQLSSPAKNAYGSPVCASRYQGQRGPTAS
CCCCEEEEEECCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCC
LSHQHFYRARFTEIGL
CCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174