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The map label for this gene is asd [H]

Identifier: 28572865

GI number: 28572865

Start: 819127

End: 820140

Strand: Reverse

Name: asd [H]

Synonym: TW724

Alternate gene names: 28572865

Gene position: 820140-819127 (Counterclockwise)

Preceding gene: 28572866

Following gene: 28572862

Centisome position: 88.57

GC content: 45.46

Gene sequence:

>1014_bases
ATGACATCGCTGGCAATTATCGGGGCTACGGGGCAGGTTGGTATCATCCTGCGCTCACTTATCGTCGAAAGGCATTTTCC
GGTTGATTCAATCCGCTTCTTTGCATCCTATGAAGGTAGAACTCTAGATTTCTATGGCAAGAAAGTACCGGTTGAAACAC
TTATTGATAAGGATTTTTCGGGAATAGACATTGCCATTTTTTCCGCGGGTGCAAATGTATCACGTAATTTTGCCCCGCAA
TTTGCAAAGGCTGGCGCACTGGTTGTTGACAACTCTTCAGCCTTCCGTATGGACCCCGGCACCCCGCTGGTTGTCAGTCA
GGTAAATCCCGATCAGATACTGCAAACAAAAACTGGTATTGTTGCGAATCCGAATTGTACAACCATGATCAGTATGCCGG
TTCTAAAACCCTTGCATGATGTATTTTCCCTGAAACGTGTTGTGTTCTCTACTTATCAGGCCGTCTCGGGGTCAGGGTTT
GCAGGTGTAAACGAACTTATCACACAAACCCTTCATGTCGCCCCAAAGATGTCTGATCTTTTATATGGAGGGTGTGACTT
CCCTGCCTCAAAGGTATACCCTAATCCGATAGCGTTTAATGCCATTCCGGTCGCTGGCAGCATTGCAGGCGATTTTGAGA
CAGAAGAAGAAAAAAAGTTACGTGATGAGTCAAGAAAAATACTCAATATTCCGGATTTACTGGTATCTGCAACATGCGTT
CGCATTCCGGTTTTTACAGGTCATTCTCTTGCAATTCACGCCGAATTTGAAAACCCAATATCACCCGGACAGGCAGGGCA
GATCCTTTCTAAAGCTGACGGTGTTGAACTTTGCGATGTACCAAACCCGATAAGTGCAACAGGCAAGAACGTTACGCTTG
TCGGTAGGCTACGAACGGATCAATCAGTTCCCCATAATATGGGCCTTGTTATGTTCATCTCTGGTGATAATTTGCGTAAA
GGTGCCGCGTTAAATGCGCTTGAAATAGCTGAGTTTGCCCTAAAATCACAATAG

Upstream 100 bases:

>100_bases
TTGTAAGGGCCAATGTTGTAGCAGAGGTTGCTCGTTTAATTCACACTTCCTTTGGCCTCGATGCTGACCTGCGTGCAGTT
GTGCACTCTGAAGGCCGTGT

Downstream 100 bases:

>100_bases
ACAAGAAGCCTCTCGCCGGAACTTAGAAATGCCTTCTGTATTGACTTTCAGTGATGCAGTGGCTTTTATCAACGTCGGGG
TGGCGGGATTTGAACCCACG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTSLAIIGATGQVGIILRSLIVERHFPVDSIRFFASYEGRTLDFYGKKVPVETLIDKDFSGIDIAIFSAGANVSRNFAPQ
FAKAGALVVDNSSAFRMDPGTPLVVSQVNPDQILQTKTGIVANPNCTTMISMPVLKPLHDVFSLKRVVFSTYQAVSGSGF
AGVNELITQTLHVAPKMSDLLYGGCDFPASKVYPNPIAFNAIPVAGSIAGDFETEEEKKLRDESRKILNIPDLLVSATCV
RIPVFTGHSLAIHAEFENPISPGQAGQILSKADGVELCDVPNPISATGKNVTLVGRLRTDQSVPHNMGLVMFISGDNLRK
GAALNALEIAEFALKSQ

Sequences:

>Translated_337_residues
MTSLAIIGATGQVGIILRSLIVERHFPVDSIRFFASYEGRTLDFYGKKVPVETLIDKDFSGIDIAIFSAGANVSRNFAPQ
FAKAGALVVDNSSAFRMDPGTPLVVSQVNPDQILQTKTGIVANPNCTTMISMPVLKPLHDVFSLKRVVFSTYQAVSGSGF
AGVNELITQTLHVAPKMSDLLYGGCDFPASKVYPNPIAFNAIPVAGSIAGDFETEEEKKLRDESRKILNIPDLLVSATCV
RIPVFTGHSLAIHAEFENPISPGQAGQILSKADGVELCDVPNPISATGKNVTLVGRLRTDQSVPHNMGLVMFISGDNLRK
GAALNALEIAEFALKSQ
>Mature_336_residues
TSLAIIGATGQVGIILRSLIVERHFPVDSIRFFASYEGRTLDFYGKKVPVETLIDKDFSGIDIAIFSAGANVSRNFAPQF
AKAGALVVDNSSAFRMDPGTPLVVSQVNPDQILQTKTGIVANPNCTTMISMPVLKPLHDVFSLKRVVFSTYQAVSGSGFA
GVNELITQTLHVAPKMSDLLYGGCDFPASKVYPNPIAFNAIPVAGSIAGDFETEEEKKLRDESRKILNIPDLLVSATCVR
IPVFTGHSLAIHAEFENPISPGQAGQILSKADGVELCDVPNPISATGKNVTLVGRLRTDQSVPHNMGLVMFISGDNLRKG
AALNALEIAEFALKSQ

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=31.1572700296736, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1789841, Length=368, Percent_Identity=26.9021739130435, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36075; Mature: 35944

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLAIIGATGQVGIILRSLIVERHFPVDSIRFFASYEGRTLDFYGKKVPVETLIDKDFS
CCCEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEEECCCCEEEECCCCCCHHHHHCCCCC
GIDIAIFSAGANVSRNFAPQFAKAGALVVDNSSAFRMDPGTPLVVSQVNPDQILQTKTGI
CCEEEEEECCCCCCCCCCCHHHHCCEEEEECCCEEEECCCCCEEEEECCHHHHHHHCCCE
VANPNCTTMISMPVLKPLHDVFSLKRVVFSTYQAVSGSGFAGVNELITQTLHVAPKMSDL
EECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHH
LYGGCDFPASKVYPNPIAFNAIPVAGSIAGDFETEEEKKLRDESRKILNIPDLLVSATCV
HCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHEEECCHHHHHHHHEE
RIPVFTGHSLAIHAEFENPISPGQAGQILSKADGVELCDVPNPISATGKNVTLVGRLRTD
EEEEEECCEEEEEEECCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEEECCC
QSVPHNMGLVMFISGDNLRKGAALNALEIAEFALKSQ
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TSLAIIGATGQVGIILRSLIVERHFPVDSIRFFASYEGRTLDFYGKKVPVETLIDKDFS
CCEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEEECCCCEEEECCCCCCHHHHHCCCCC
GIDIAIFSAGANVSRNFAPQFAKAGALVVDNSSAFRMDPGTPLVVSQVNPDQILQTKTGI
CCEEEEEECCCCCCCCCCCHHHHCCEEEEECCCEEEECCCCCEEEEECCHHHHHHHCCCE
VANPNCTTMISMPVLKPLHDVFSLKRVVFSTYQAVSGSGFAGVNELITQTLHVAPKMSDL
EECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHH
LYGGCDFPASKVYPNPIAFNAIPVAGSIAGDFETEEEKKLRDESRKILNIPDLLVSATCV
HCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHEEECCHHHHHHHHEE
RIPVFTGHSLAIHAEFENPISPGQAGQILSKADGVELCDVPNPISATGKNVTLVGRLRTD
EEEEEECCEEEEEEECCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEEECCC
QSVPHNMGLVMFISGDNLRKGAALNALEIAEFALKSQ
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8100567 [H]