Click here to switch to the map view.

The map label for this gene is mshD [H]

Identifier: 28572823

GI number: 28572823

Start: 770211

End: 771188

Strand: Direct

Name: mshD [H]

Synonym: TW682

Alternate gene names: 28572823

Gene position: 770211-771188 (Clockwise)

Preceding gene: 28572817

Following gene: 28572824

Centisome position: 83.18

GC content: 44.38

Gene sequence:

>978_bases
GTGCCATTCGACGAAAGTCGATTGCGGAAAGTTGCCGCTGTCTGCCAGCAATTTGACTCACACCCTCCTTTTTCTGACTA
TACGCTTTTGGGCAAGCCAAGCGTATTATGTCTTATGTCTGACAAAACCCTGCATAACTCGACTGGAAGTGATTTTTTCT
GTCCAAATCCCCTTGATATAGAGTGGCAAATTACATTAGGTATAGCCCTCGTAAACGGCAATGAGGCAGAAATGGTGATA
ATTCCAGGGCACAGGAAAAACGGTTACGGGACATACTTCCTCAATGAAATACGTAAGCGTATCCCGGGCGATGTAAAATT
CTGGGCACACGGAGCCCATCCAGCCGCGCTGGCCCTTGCAAAAAGATATGGGGCTACAGAGGAACGTGTTGTGTGCATAA
TGCATCTCAAAAACCCCAGAGCGCGAGTAAAATCCTTGTTGCAATCCCTTAGTCGAATGCGGTGGATTGAATATGCAAAG
CGAGTTTTGCAAAAAGTGGCGTTCTTATCACGCAGAGGAGCGGTAGAGTCAGTTACCTATAGGTGTTTTAGGACAGGTAG
GGGCACGAAAGCAACTCGTGATGAGATTGAATGGCTAGCCCTCAATGCAGAAATTTTTAAAGATCATCCGGAGTATGGGA
AGCTGACGATAAATGACCTCAGGCTTTGCTACTCGCAACCTTGGTTTAGCAGGAAAAGATTCATACTTGCGATAAAGAAT
GGGAAGGTTGCGGGTTATGTTTGGATAAAACTCAATAAGCACAGCCGTAAAGGGGAAATTTACTCTCTGGGAAGCACCGG
TGGTGGATTGGGTAGCAAATTATTGGAGCGAGCGCTTGACATAATGTACAGAAGGGGTGTTGAACTCATTTTTTTATATG
TCGATGAGACAAACAAAAAAGCAATAAACCTCTATAGAAAATTTAATTTCGCAGAAGTTGAAAGAGACATTTTGTTCAAT
GTACGGGGAGGAAGATGA

Upstream 100 bases:

>100_bases
TCGCCTACCAGATGATTCTAATACGAGACTCTAAACACGGAACAATATCGAATACCATTGATGTTAAATGTCATTGTCTG
AAAAACTGCTTGTCAGAGAG

Downstream 100 bases:

>100_bases
AGCAGAAGGTCTGTGAAGAATTCTCACAAATAGTTAGGGTTGTGTAGATGAGCGAGGCGCAAAATGGATCAATCCCAAAC
GACAAGTGGGTGATACAAAT

Product: acetyltransferase

Products: NA

Alternate protein names: MSH acetyltransferase; Mycothiol synthase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MPFDESRLRKVAAVCQQFDSHPPFSDYTLLGKPSVLCLMSDKTLHNSTGSDFFCPNPLDIEWQITLGIALVNGNEAEMVI
IPGHRKNGYGTYFLNEIRKRIPGDVKFWAHGAHPAALALAKRYGATEERVVCIMHLKNPRARVKSLLQSLSRMRWIEYAK
RVLQKVAFLSRRGAVESVTYRCFRTGRGTKATRDEIEWLALNAEIFKDHPEYGKLTINDLRLCYSQPWFSRKRFILAIKN
GKVAGYVWIKLNKHSRKGEIYSLGSTGGGLGSKLLERALDIMYRRGVELIFLYVDETNKKAINLYRKFNFAEVERDILFN
VRGGR

Sequences:

>Translated_325_residues
MPFDESRLRKVAAVCQQFDSHPPFSDYTLLGKPSVLCLMSDKTLHNSTGSDFFCPNPLDIEWQITLGIALVNGNEAEMVI
IPGHRKNGYGTYFLNEIRKRIPGDVKFWAHGAHPAALALAKRYGATEERVVCIMHLKNPRARVKSLLQSLSRMRWIEYAK
RVLQKVAFLSRRGAVESVTYRCFRTGRGTKATRDEIEWLALNAEIFKDHPEYGKLTINDLRLCYSQPWFSRKRFILAIKN
GKVAGYVWIKLNKHSRKGEIYSLGSTGGGLGSKLLERALDIMYRRGVELIFLYVDETNKKAINLYRKFNFAEVERDILFN
VRGGR
>Mature_324_residues
PFDESRLRKVAAVCQQFDSHPPFSDYTLLGKPSVLCLMSDKTLHNSTGSDFFCPNPLDIEWQITLGIALVNGNEAEMVII
PGHRKNGYGTYFLNEIRKRIPGDVKFWAHGAHPAALALAKRYGATEERVVCIMHLKNPRARVKSLLQSLSRMRWIEYAKR
VLQKVAFLSRRGAVESVTYRCFRTGRGTKATRDEIEWLALNAEIFKDHPEYGKLTINDLRLCYSQPWFSRKRFILAIKNG
KVAGYVWIKLNKHSRKGEIYSLGSTGGGLGSKLLERALDIMYRRGVELIFLYVDETNKKAINLYRKFNFAEVERDILFNV
RGGR

Specific function: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol [H]

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 N-acetyltransferase domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR017813 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.189 [H]

Molecular weight: Translated: 37253; Mature: 37122

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDESRLRKVAAVCQQFDSHPPFSDYTLLGKPSVLCLMSDKTLHNSTGSDFFCPNPLDI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCE
EWQITLGIALVNGNEAEMVIIPGHRKNGYGTYFLNEIRKRIPGDVKFWAHGAHPAALALA
EEEEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
KRYGATEERVVCIMHLKNPRARVKSLLQSLSRMRWIEYAKRVLQKVAFLSRRGAVESVTY
HHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RCFRTGRGTKATRDEIEWLALNAEIFKDHPEYGKLTINDLRLCYSQPWFSRKRFILAIKN
HHHHCCCCCCCCHHCEEEEEECHHHHCCCCCCCCEEHHHHHHHHCCCCCCCCEEEEEEEC
GKVAGYVWIKLNKHSRKGEIYSLGSTGGGLGSKLLERALDIMYRRGVELIFLYVDETNKK
CCEEEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCH
AINLYRKFNFAEVERDILFNVRGGR
HHHHHHHCCHHHHCEEEEEEECCCC
>Mature Secondary Structure 
PFDESRLRKVAAVCQQFDSHPPFSDYTLLGKPSVLCLMSDKTLHNSTGSDFFCPNPLDI
CCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCE
EWQITLGIALVNGNEAEMVIIPGHRKNGYGTYFLNEIRKRIPGDVKFWAHGAHPAALALA
EEEEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
KRYGATEERVVCIMHLKNPRARVKSLLQSLSRMRWIEYAKRVLQKVAFLSRRGAVESVTY
HHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RCFRTGRGTKATRDEIEWLALNAEIFKDHPEYGKLTINDLRLCYSQPWFSRKRFILAIKN
HHHHCCCCCCCCHHCEEEEEECHHHHCCCCCCCCEEHHHHHHHHCCCCCCCCEEEEEEEC
GKVAGYVWIKLNKHSRKGEIYSLGSTGGGLGSKLLERALDIMYRRGVELIFLYVDETNKK
CCEEEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCH
AINLYRKFNFAEVERDILFNVRGGR
HHHHHHHCCHHHHCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA