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The map label for this gene is ppa2 [H]

Identifier: 28572764

GI number: 28572764

Start: 703479

End: 703958

Strand: Reverse

Name: ppa2 [H]

Synonym: TW618

Alternate gene names: 28572764

Gene position: 703958-703479 (Counterclockwise)

Preceding gene: 28572765

Following gene: 28572763

Centisome position: 76.03

GC content: 44.17

Gene sequence:

>480_bases
ATGCAGACACTTACTGCTATTGTTGAGATTCCCCGTGGCAGCCGCAGTAAATACGAGATAGATAAGAAAACAGGTCGTCT
TTTCCTAGATCGTGTCGTATCAACTGCATTCGGCTACCCAACAAATTATGGATTCATCGAGAACACCCTAGCCCTTGATG
GTGATCCAATCGATGCCCTAATACTTGTTCAGAACCAGCTTTTCCCCGGTGTTGCCCTACATATCCGCCCTGTTGGTGTC
CTCCATATGACTGATGATGGTGGTGAGGATGACAAGGTTCTATGTGTTGCCCTGAAAGATCCTTACTGTGATCATATAAA
TGATCTAGATGATGTACCAAAGCATGTGCTAAACCAAATAGAGCACTTCTTCCAACACTACAAAGATCTAGAAGAAGGTA
AATGGGTAAAGCTTGGTGCCTGGAATGGTAAAGATAAGGCCATGGAGATTATCACAGAAGGCCTATCCCGCTTCAACTAA

Upstream 100 bases:

>100_bases
AGGTAAAGGTAGCTGCACGTAACGCTGCCATTACCTTAGTTGTTGCAATTATCTCTGCAGTCTCCTCTTGGTTTGCTATT
ACTAAGTGGTTCGCTTAAGG

Downstream 100 bases:

>100_bases
TAATCCTGTGTATGAGCCTCTGCAGGTATCAAACTAGCAGCATCCTTGTCTGCAAAGATAATAGTCTCTAACCTTCCCCT
TACACCAGCTATAGGCAGCT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQTLTAIVEIPRGSRSKYEIDKKTGRLFLDRVVSTAFGYPTNYGFIENTLALDGDPIDALILVQNQLFPGVALHIRPVGV
LHMTDDGGEDDKVLCVALKDPYCDHINDLDDVPKHVLNQIEHFFQHYKDLEEGKWVKLGAWNGKDKAMEIITEGLSRFN

Sequences:

>Translated_159_residues
MQTLTAIVEIPRGSRSKYEIDKKTGRLFLDRVVSTAFGYPTNYGFIENTLALDGDPIDALILVQNQLFPGVALHIRPVGV
LHMTDDGGEDDKVLCVALKDPYCDHINDLDDVPKHVLNQIEHFFQHYKDLEEGKWVKLGAWNGKDKAMEIITEGLSRFN
>Mature_159_residues
MQTLTAIVEIPRGSRSKYEIDKKTGRLFLDRVVSTAFGYPTNYGFIENTLALDGDPIDALILVQNQLFPGVALHIRPVGV
LHMTDDGGEDDKVLCVALKDPYCDHINDLDDVPKHVLNQIEHFFQHYKDLEEGKWVKLGAWNGKDKAMEIITEGLSRFN

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=160, Percent_Identity=48.125, Blast_Score=153, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6319483, Length=177, Percent_Identity=29.3785310734463, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 17955; Mature: 17955

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLTAIVEIPRGSRSKYEIDKKTGRLFLDRVVSTAFGYPTNYGFIENTLALDGDPIDAL
CCHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCEECCEEEECCCCCEEE
ILVQNQLFPGVALHIRPVGVLHMTDDGGEDDKVLCVALKDPYCDHINDLDDVPKHVLNQI
EEEECCCCCCEEEEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
EHFFQHYKDLEEGKWVKLGAWNGKDKAMEIITEGLSRFN
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTLTAIVEIPRGSRSKYEIDKKTGRLFLDRVVSTAFGYPTNYGFIENTLALDGDPIDAL
CCHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCEECCEEEECCCCCEEE
ILVQNQLFPGVALHIRPVGVLHMTDDGGEDDKVLCVALKDPYCDHINDLDDVPKHVLNQI
EEEECCCCCCEEEEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
EHFFQHYKDLEEGKWVKLGAWNGKDKAMEIITEGLSRFN
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA