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The map label for this gene is gds [H]

Identifier: 28572702

GI number: 28572702

Start: 589617

End: 590681

Strand: Direct

Name: gds [H]

Synonym: TW554

Alternate gene names: 28572702

Gene position: 589617-590681 (Clockwise)

Preceding gene: 28572687

Following gene: 28572703

Centisome position: 63.68

GC content: 42.82

Gene sequence:

>1065_bases
ATGACACTTCTGGAAATGGTAAATACGAAAATAAGTCGTTTTATTCTGAATAACAAAACATCAAAACATACGGAAAGTAT
GTATGATTATCTACAAGACTTCACATTCGGTGGAAAAAGGCTGAGGGCGAAGCTTTGCTTTACCGGTGCTGAGTGCATAG
GGCCAATTCCAGAAAATCTTTTTGAATTAATTTCTGATATCGCTGTTGCAATAGAGCTGTTTCACGCAGCGGCGCTCGTG
CATGATGATCTGATTGATAAATCTGATTCCCGCCGTGGGTTGCCGGCGGTACACAAAAGATTTGCCAAGTTTCATGAAGA
AAACTCATTTGTAAAATGCAAAGAGAATTTTGGCACCGCAAGTGCAATTCTTGCAGGAGACATGCTGCTTGTATGGAGCA
GTAGGTTCTTTTATTCAGCATTGAACAATCTCCTAAACACCACTGCAAAACAAGCCTCTGATTTTCACCTGGACACGATG
AATATCCTATGGCACGAAATGCAAAACGAAGTTGTTATAGGCCAGTACATGGATGTTCTGCACGAACACAGATGGAGACA
GTTGTCTGTACAAGAGGCCCTGGATATATCAAAAGAAATCATGATAAAAAAGTCTGGGAAGTACTCGGTGCAAGTTCCCC
TTTGTCTTGGCGCCAATACGAACGGTGCAACAATAGAACACCTAGAGGTTTTAAAAAGATTCTCTCTCCCAATAGGCCTT
GCATTTCAGATGCGCAATGACATAGACGGCGCGTTTGCGAATGACAAAATAACCGGTAAACCATCCAGTGATCTATCATC
TGCAAAGCACACAATGCTAATCGGCCTTGCGCGGATACACAGCACGAAACACGGGCGAATAAGGCTAGAGGAGATACTTG
GACAGGCAGATAATGAAGAGGAAATAAGGGCTATAGTCACCGAAAGCGGCGCCCTAAGAGAAGCTGAAAATCTCATCAAA
AAATGGACTGATCAGGCTATGGAAATTATCAAAGAAGCGCGGCTGCACAGTATGGGTAAGGAAAAACTAATCAAAATTGC
CTCCTGGCTGTCACAAGCAACATAA

Upstream 100 bases:

>100_bases
TCACCTATAATCAAGACTACTCCATGTGTCCGTTTTTCATGTGTCTGTTTTTCCTACTAGAAAGGTACCCTGCCATTGTC
AGGATAAATTCGGGTGCTTT

Downstream 100 bases:

>100_bases
AATGATCTCATGAGGGATGCAGCTTCCGTAATAGGCATGCGCATAGCGGACCGTTACCTCATTACCGAGAAAATAGCATC
CGGCGGTATGGCCACGGTGT

Product: polyprenyl diphosphate synthase

Products: NA

Alternate protein names: GGPP synthase; GGPS; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranyltranstransferase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTLLEMVNTKISRFILNNKTSKHTESMYDYLQDFTFGGKRLRAKLCFTGAECIGPIPENLFELISDIAVAIELFHAAALV
HDDLIDKSDSRRGLPAVHKRFAKFHEENSFVKCKENFGTASAILAGDMLLVWSSRFFYSALNNLLNTTAKQASDFHLDTM
NILWHEMQNEVVIGQYMDVLHEHRWRQLSVQEALDISKEIMIKKSGKYSVQVPLCLGANTNGATIEHLEVLKRFSLPIGL
AFQMRNDIDGAFANDKITGKPSSDLSSAKHTMLIGLARIHSTKHGRIRLEEILGQADNEEEIRAIVTESGALREAENLIK
KWTDQAMEIIKEARLHSMGKEKLIKIASWLSQAT

Sequences:

>Translated_354_residues
MTLLEMVNTKISRFILNNKTSKHTESMYDYLQDFTFGGKRLRAKLCFTGAECIGPIPENLFELISDIAVAIELFHAAALV
HDDLIDKSDSRRGLPAVHKRFAKFHEENSFVKCKENFGTASAILAGDMLLVWSSRFFYSALNNLLNTTAKQASDFHLDTM
NILWHEMQNEVVIGQYMDVLHEHRWRQLSVQEALDISKEIMIKKSGKYSVQVPLCLGANTNGATIEHLEVLKRFSLPIGL
AFQMRNDIDGAFANDKITGKPSSDLSSAKHTMLIGLARIHSTKHGRIRLEEILGQADNEEEIRAIVTESGALREAENLIK
KWTDQAMEIIKEARLHSMGKEKLIKIASWLSQAT
>Mature_353_residues
TLLEMVNTKISRFILNNKTSKHTESMYDYLQDFTFGGKRLRAKLCFTGAECIGPIPENLFELISDIAVAIELFHAAALVH
DDLIDKSDSRRGLPAVHKRFAKFHEENSFVKCKENFGTASAILAGDMLLVWSSRFFYSALNNLLNTTAKQASDFHLDTMN
ILWHEMQNEVVIGQYMDVLHEHRWRQLSVQEALDISKEIMIKKSGKYSVQVPLCLGANTNGATIEHLEVLKRFSLPIGLA
FQMRNDIDGAFANDKITGKPSSDLSSAKHTMLIGLARIHSTKHGRIRLEEILGQADNEEEIRAIVTESGALREAENLIKK
WTDQAMEIIKEARLHSMGKEKLIKIASWLSQAT

Specific function: Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate which is a precursor of the ether-linked lipids [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.29; =2.5.1.10 [H]

Molecular weight: Translated: 39959; Mature: 39827

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLEMVNTKISRFILNNKTSKHTESMYDYLQDFTFGGKRLRAKLCFTGAECIGPIPENL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHCCCCHHHH
FELISDIAVAIELFHAAALVHDDLIDKSDSRRGLPAVHKRFAKFHEENSFVKCKENFGTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHH
SAILAGDMLLVWSSRFFYSALNNLLNTTAKQASDFHLDTMNILWHEMQNEVVIGQYMDVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEHHHHHHHH
HEHRWRQLSVQEALDISKEIMIKKSGKYSVQVPLCLGANTNGATIEHLEVLKRFSLPIGL
HHHHHHHHHHHHHHCCHHHHHEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCE
AFQMRNDIDGAFANDKITGKPSSDLSSAKHTMLIGLARIHSTKHGRIRLEEILGQADNEE
EEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCHH
EIRAIVTESGALREAENLIKKWTDQAMEIIKEARLHSMGKEKLIKIASWLSQAT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLEMVNTKISRFILNNKTSKHTESMYDYLQDFTFGGKRLRAKLCFTGAECIGPIPENL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHCCCCHHHH
FELISDIAVAIELFHAAALVHDDLIDKSDSRRGLPAVHKRFAKFHEENSFVKCKENFGTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHH
SAILAGDMLLVWSSRFFYSALNNLLNTTAKQASDFHLDTMNILWHEMQNEVVIGQYMDVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEHHHHHHHH
HEHRWRQLSVQEALDISKEIMIKKSGKYSVQVPLCLGANTNGATIEHLEVLKRFSLPIGL
HHHHHHHHHHHHHHCCHHHHHEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCE
AFQMRNDIDGAFANDKITGKPSSDLSSAKHTMLIGLARIHSTKHGRIRLEEILGQADNEE
EEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCHH
EIRAIVTESGALREAENLIKKWTDQAMEIIKEARLHSMGKEKLIKIASWLSQAT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]