Click here to switch to the map view.

The map label for this gene is lgt

Identifier: 28572613

GI number: 28572613

Start: 499790

End: 500608

Strand: Reverse

Name: lgt

Synonym: TW463

Alternate gene names: 28572613

Gene position: 500608-499790 (Counterclockwise)

Preceding gene: 28572615

Following gene: 28572611

Centisome position: 54.06

GC content: 42.25

Gene sequence:

>819_bases
ATGCATTTTTACATACCACCACCGCCTATATCCGGATTTTGGCTCGGGCCCTTATATGTGCATATGTATTCCGTATTTAT
GCTTGCAGGGGCACTGGTTTTATTCGAGTTAACAAATAGGCGTTTTATTGTCCTTACCGGTAACAGAGAGTTTACGGCCT
TCGCTGTTACATCCCTATTGATTCCTGTTATTTTGGGAGCGCGATTGTGGCATGTCGTGAGCCACACGCAGATGTATGAA
CATCAGCCCTTTTACAAGGTATTCGCCATATGGCAGGGTGGTCTTGGGTTTATTGGTGGGGTATTCTCTGGGCTTATATG
CTTTTTTGTTATCGCAAAAATAAAAAAAGTACCACCCTTTACTTTTCTTGACGCCCTGGCTCCAGGAATTTTGGTTGCTT
TATGCTTTGCAAGATTGGGAAATTACTTCAACGGTGAGGTGTTTGGAACTGAGACAACTCTTCCGTGGGGTTTAAAGCTT
AGTCATGAGGGGTTTAAGGATTTGAATGTTGAAAAATATTTTCATCCGATTTTTCTGTATGAAATTATCCTTAATGTGTT
CATTATTGTCATCCTCTTGGTTCTAGAAAAAAGAGTATTTGTAAAAACAGTTTTTCCAAAAGGTTCCGTGTTTGCTGCGT
TTCTCGTGCTGTATGGCCTAGGAAGATTTGCTCTCGAACCTATGCGTTACAATCTGCAGCAGAACTCATTCGGTCTGGAC
CTTAATTATGTCGGTGCGGCTGCGATGATTATTGTGGGTGTTTTGATTGCTTGCAGACACACTATTGCGAGCGGAAAACT
CAGGAACTCCGGGGATTAG

Upstream 100 bases:

>100_bases
ACCGGGGCCTCGCACAGACAAAGGCATGCAGTACCACTAAGTATATTTCACGCAGGCCCAGCAAGTCTTTATCACTGCAA
GCTTTTAAAATATAAGGGAA

Downstream 100 bases:

>100_bases
TGTCCAAAGCTCTCACTCCTTGGGCTCTTGCGGAACCCAATATTTGCCCGGAATACCCCACTTGTTATTTAGAACTGCTT
GGCGAACCTCTCCGGAATAT

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MHFYIPPPPISGFWLGPLYVHMYSVFMLAGALVLFELTNRRFIVLTGNREFTAFAVTSLLIPVILGARLWHVVSHTQMYE
HQPFYKVFAIWQGGLGFIGGVFSGLICFFVIAKIKKVPPFTFLDALAPGILVALCFARLGNYFNGEVFGTETTLPWGLKL
SHEGFKDLNVEKYFHPIFLYEIILNVFIIVILLVLEKRVFVKTVFPKGSVFAAFLVLYGLGRFALEPMRYNLQQNSFGLD
LNYVGAAAMIIVGVLIACRHTIASGKLRNSGD

Sequences:

>Translated_272_residues
MHFYIPPPPISGFWLGPLYVHMYSVFMLAGALVLFELTNRRFIVLTGNREFTAFAVTSLLIPVILGARLWHVVSHTQMYE
HQPFYKVFAIWQGGLGFIGGVFSGLICFFVIAKIKKVPPFTFLDALAPGILVALCFARLGNYFNGEVFGTETTLPWGLKL
SHEGFKDLNVEKYFHPIFLYEIILNVFIIVILLVLEKRVFVKTVFPKGSVFAAFLVLYGLGRFALEPMRYNLQQNSFGLD
LNYVGAAAMIIVGVLIACRHTIASGKLRNSGD
>Mature_272_residues
MHFYIPPPPISGFWLGPLYVHMYSVFMLAGALVLFELTNRRFIVLTGNREFTAFAVTSLLIPVILGARLWHVVSHTQMYE
HQPFYKVFAIWQGGLGFIGGVFSGLICFFVIAKIKKVPPFTFLDALAPGILVALCFARLGNYFNGEVFGTETTLPWGLKL
SHEGFKDLNVEKYFHPIFLYEIILNVFIIVILLVLEKRVFVKTVFPKGSVFAAFLVLYGLGRFALEPMRYNLQQNSFGLD
LNYVGAAAMIIVGVLIACRHTIASGKLRNSGD

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=269, Percent_Identity=26.7657992565056, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_TROW8 (Q83HQ2)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789393.1
- STRING:   Q83HQ2
- GeneID:   1064304
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW463
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   FESIRID
- ProtClustDB:   PRK00052
- BioCyc:   TWHI218496:TW0438-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 30525; Mature: 30525

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb9a50f8)-; HASH(0x96864e0)-; HASH(0xc360b5c)-; HASH(0xc3aa91c)-; HASH(0xc645e74)-; HASH(0xc0e733c)-; HASH(0xb0838c0)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFYIPPPPISGFWLGPLYVHMYSVFMLAGALVLFELTNRRFIVLTGNREFTAFAVTSLL
CCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
IPVILGARLWHVVSHTQMYEHQPFYKVFAIWQGGLGFIGGVFSGLICFFVIAKIKKVPPF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCH
TFLDALAPGILVALCFARLGNYFNGEVFGTETTLPWGLKLSHEGFKDLNVEKYFHPIFLY
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
EIILNVFIIVILLVLEKRVFVKTVFPKGSVFAAFLVLYGLGRFALEPMRYNLQQNSFGLD
HHHHHHHHHHHHHHHCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LNYVGAAAMIIVGVLIACRHTIASGKLRNSGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure
MHFYIPPPPISGFWLGPLYVHMYSVFMLAGALVLFELTNRRFIVLTGNREFTAFAVTSLL
CCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
IPVILGARLWHVVSHTQMYEHQPFYKVFAIWQGGLGFIGGVFSGLICFFVIAKIKKVPPF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCH
TFLDALAPGILVALCFARLGNYFNGEVFGTETTLPWGLKLSHEGFKDLNVEKYFHPIFLY
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
EIILNVFIIVILLVLEKRVFVKTVFPKGSVFAAFLVLYGLGRFALEPMRYNLQQNSFGLD
HHHHHHHHHHHHHHHCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LNYVGAAAMIIVGVLIACRHTIASGKLRNSGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12606174