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The map label for this gene is xylH [H]

Identifier: 28572593

GI number: 28572593

Start: 481622

End: 482845

Strand: Direct

Name: xylH [H]

Synonym: TW442

Alternate gene names: 28572593

Gene position: 481622-482845 (Clockwise)

Preceding gene: 28572592

Following gene: 28572594

Centisome position: 52.01

GC content: 45.34

Gene sequence:

>1224_bases
ATGAAAATTAAACTTTTTTCTAGTAGAAATTTTGGGATTCTTGTTGCAGCCGTTGCGGTCGCTCTGTTTTTTCAGGTAGC
TTCAGGCGGTAGGATGCTGACAAGCGACAATGTGCTCAATATTGTCAATGGAAACAGCCATATCTTTATTTTGTCGATTG
GCATGGTGCTTGTAATTGTTTCGGGCAATATTGATCTTTCAGTTGGTTCTGTTGCTGCCTTTGTTGGAATAGTTGTTGCC
GTTGCTACCGATAGCTTTCATTTAAGCGCATGGCAAGCCATTATCCTGGGGCTGCTAATTGGGCTTGTAGTCGGGTGTTG
GCAGGCTTTTTGGGTTGCCTTTGTGGGTATCCCGGCTTTTATTGCCACTTTGGCTGGCATGCTTACTTTCAGAGGTCTCA
ATCAGCTTGTGGGCAATTCTCGGTCAGTACCCGTGCCAGATGATTTTACTTACTTTGGTGCCGGTTATCTCCCCGATATA
TTCACTAACACTGCGTTCAATGTCCCGACAGTTATTTTGGGCTTTGTTGTCTTCCTGCTGTTAGTGATAATGCAGATACT
TCGCAGGCGCAACAGGAAGCTACTTGGCATTCAGCAAGAGAATATTCCCGTATTTTTACTGAGAATCGCAATATATGGGC
TTGCCGTGGCGTATCTCACATATCTCTTTGCCACAGGTCATCCCGGGACAAGCTTCCCAATTCCTGGTCTAATATTTGTT
GTTATTGCTTTTATCTATGTATTCATCTCCGAGAGAACCATCCTTGGAAGGCATATATATGCTGTTGGCGGTAATAGAAA
TGCAGCCATTCTCTCTGGTGTCAGTGTGAAAAGAGTTAATTTCTTTGTCATGGCAAACATGTCAATTCTTGCCAGTATTG
CGGGCATGATGTTTGTTGGTCGCTCTGGAGGGTCTGGTCCATCTGATGGTGTTGGATGGGAACTTGACGCAATAGCTGCT
GTATTTGTCGGCGGCGCGGCCGTCAGCGGTGGTGTTGGGACAGTTATTGGCGCATGCCTTGGTGGTGTGGTTGTTGCCCT
TCTAAGTAACGGCTTGCTTATCATGGGTATTAGTGCTGATATAGCTGCGATTATCAAGGGTTTAGTTTTGTTGGCAGCTG
TTTCTTTTGATGTCGTTAGTAAAAACCGGGAAAAACCGTCTATAATCAGATTGTTTGTACGACGAAGTGGACTTTCGCGG
GATAAGGCCGGTGGTCGAGGATGA

Upstream 100 bases:

>100_bases
CGTATATATACTCTGTTTGAGGGTAAAGTAACTGGGGAGTTTAAAACTTCAGAGGCTAGCCAGGAGCTACTTATGCGTTA
TATGACTTCATATGGAAATA

Downstream 100 bases:

>100_bases
TCCGGTCTGTTGAGTTTGAGAGTAATTGAAAGGATTCGGTATGTCCATCTCAAAAGGGTTATTCAGGGCGGTTTTATTTA
CGGCTGCCGCGTCATTGTTT

Product: sugar ABC transporter permease subunit

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKIKLFSSRNFGILVAAVAVALFFQVASGGRMLTSDNVLNIVNGNSHIFILSIGMVLVIVSGNIDLSVGSVAAFVGIVVA
VATDSFHLSAWQAIILGLLIGLVVGCWQAFWVAFVGIPAFIATLAGMLTFRGLNQLVGNSRSVPVPDDFTYFGAGYLPDI
FTNTAFNVPTVILGFVVFLLLVIMQILRRRNRKLLGIQQENIPVFLLRIAIYGLAVAYLTYLFATGHPGTSFPIPGLIFV
VIAFIYVFISERTILGRHIYAVGGNRNAAILSGVSVKRVNFFVMANMSILASIAGMMFVGRSGGSGPSDGVGWELDAIAA
VFVGGAAVSGGVGTVIGACLGGVVVALLSNGLLIMGISADIAAIIKGLVLLAAVSFDVVSKNREKPSIIRLFVRRSGLSR
DKAGGRG

Sequences:

>Translated_407_residues
MKIKLFSSRNFGILVAAVAVALFFQVASGGRMLTSDNVLNIVNGNSHIFILSIGMVLVIVSGNIDLSVGSVAAFVGIVVA
VATDSFHLSAWQAIILGLLIGLVVGCWQAFWVAFVGIPAFIATLAGMLTFRGLNQLVGNSRSVPVPDDFTYFGAGYLPDI
FTNTAFNVPTVILGFVVFLLLVIMQILRRRNRKLLGIQQENIPVFLLRIAIYGLAVAYLTYLFATGHPGTSFPIPGLIFV
VIAFIYVFISERTILGRHIYAVGGNRNAAILSGVSVKRVNFFVMANMSILASIAGMMFVGRSGGSGPSDGVGWELDAIAA
VFVGGAAVSGGVGTVIGACLGGVVVALLSNGLLIMGISADIAAIIKGLVLLAAVSFDVVSKNREKPSIIRLFVRRSGLSR
DKAGGRG
>Mature_407_residues
MKIKLFSSRNFGILVAAVAVALFFQVASGGRMLTSDNVLNIVNGNSHIFILSIGMVLVIVSGNIDLSVGSVAAFVGIVVA
VATDSFHLSAWQAIILGLLIGLVVGCWQAFWVAFVGIPAFIATLAGMLTFRGLNQLVGNSRSVPVPDDFTYFGAGYLPDI
FTNTAFNVPTVILGFVVFLLLVIMQILRRRNRKLLGIQQENIPVFLLRIAIYGLAVAYLTYLFATGHPGTSFPIPGLIFV
VIAFIYVFISERTILGRHIYAVGGNRNAAILSGVSVKRVNFFVMANMSILASIAGMMFVGRSGGSGPSDGVGWELDAIAA
VFVGGAAVSGGVGTVIGACLGGVVVALLSNGLLIMGISADIAAIIKGLVLLAAVSFDVVSKNREKPSIIRLFVRRSGLSR
DKAGGRG

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=383, Percent_Identity=35.7702349869452, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1790191, Length=155, Percent_Identity=38.7096774193548, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788896, Length=155, Percent_Identity=36.7741935483871, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790524, Length=173, Percent_Identity=32.9479768786127, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693152, Length=212, Percent_Identity=27.8301886792453, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082395, Length=159, Percent_Identity=34.5911949685535, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787794, Length=165, Percent_Identity=26.0606060606061, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693214, Length=154, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 42785; Mature: 42785

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKLFSSRNFGILVAAVAVALFFQVASGGRMLTSDNVLNIVNGNSHIFILSIGMVLVIV
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCEEEEEECCEEEEEE
SGNIDLSVGSVAAFVGIVVAVATDSFHLSAWQAIILGLLIGLVVGCWQAFWVAFVGIPAF
ECCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLAGMLTFRGLNQLVGNSRSVPVPDDFTYFGAGYLPDIFTNTAFNVPTVILGFVVFLL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
LVIMQILRRRNRKLLGIQQENIPVFLLRIAIYGLAVAYLTYLFATGHPGTSFPIPGLIFV
HHHHHHHHHCCCCEECEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VIAFIYVFISERTILGRHIYAVGGNRNAAILSGVSVKRVNFFVMANMSILASIAGMMFVG
HHHHHHHHHHCCCEECCEEEEECCCCCEEEEECCEEEHEEEEEEECHHHHHHHHHHHEEC
RSGGSGPSDGVGWELDAIAAVFVGGAAVSGGVGTVIGACLGGVVVALLSNGLLIMGISAD
CCCCCCCCCCCCCHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHH
IAAIIKGLVLLAAVSFDVVSKNREKPSIIRLFVRRSGLSRDKAGGRG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKIKLFSSRNFGILVAAVAVALFFQVASGGRMLTSDNVLNIVNGNSHIFILSIGMVLVIV
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCEEEEEECCEEEEEE
SGNIDLSVGSVAAFVGIVVAVATDSFHLSAWQAIILGLLIGLVVGCWQAFWVAFVGIPAF
ECCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLAGMLTFRGLNQLVGNSRSVPVPDDFTYFGAGYLPDIFTNTAFNVPTVILGFVVFLL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
LVIMQILRRRNRKLLGIQQENIPVFLLRIAIYGLAVAYLTYLFATGHPGTSFPIPGLIFV
HHHHHHHHHCCCCEECEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VIAFIYVFISERTILGRHIYAVGGNRNAAILSGVSVKRVNFFVMANMSILASIAGMMFVG
HHHHHHHHHHCCCEECCEEEEECCCCCEEEEECCEEEHEEEEEEECHHHHHHHHHHHEEC
RSGGSGPSDGVGWELDAIAAVFVGGAAVSGGVGTVIGACLGGVVVALLSNGLLIMGISAD
CCCCCCCCCCCCCHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHH
IAAIIKGLVLLAAVSFDVVSKNREKPSIIRLFVRRSGLSRDKAGGRG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]