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The map label for this gene is sufB [H]

Identifier: 28572585

GI number: 28572585

Start: 473664

End: 475085

Strand: Direct

Name: sufB [H]

Synonym: TW434

Alternate gene names: 28572585

Gene position: 473664-475085 (Clockwise)

Preceding gene: 28572583

Following gene: 28572586

Centisome position: 51.16

GC content: 47.4

Gene sequence:

>1422_bases
GTGAGCGAAAATCTTATCGCCAATAGACCTGACCTTGATAGCCTGGGGAAGTATGAGTATGGGTGGCACGATTCAGATCG
TGCTGGGTCAGACGCCAGGCGGGGTCTATCGCGCGATGTTGTAGAGGAAATATCCGAAACCAAGGGGGAACCTGACTGGA
TGCGCTCAATGCGCCTCAGGGCACTTGAAATCTTTTATCGCAAGCCAATGCCAAACTGGGGCGCTGATCTGACTGGAATT
GATTTTGACCAAATAAAGTACTTTGTACGTTCAACTGAACGACAGGCCAATTCTTGGGAGGATTTGCCAGAAGAAATACG
TAATACATACGAAAGGCTGGGCATTCCGGATGCCGAGCGGCAGCGTCTTGTGGCAGGTGTTGCTGCACAGTACGAATCAG
AGGTTGTATACCACCAGATAAATGCTGAGCTCGAACGGCAGGGGGTGGTTTTTCTGGACACAGATACAGCCCTCAAAGAG
CACCCGGATATTCTGCGTAAGTATTTTGGGTCAGTTATTCCAGCGGGAGATAATAAGTTTGCCGCACTGAACACCGCCGT
TTGGTCCGGGGGGTCTTTTGTATATGTGCCAGAAGGTGTTAAGGTCGAAATTCCCCTTCAAGCGTATTTCAGGATTAATA
CCGAGAATATGGGTCAATTTGAGCGCACCCTGATTATTGCCGATAAAAACAGCTACGTTCACTATGTTGAGGGGTGCACA
GCTCCAATATATAGTTCGCATTCACTGCATTCCGCGGTTGTCGAAATTCTTGTAAAAGAAGGTGCAAGGGTGCGTTATAC
AACTGTTCAAAACTGGTCTACTAATGTCTACAACCTGGTAACGAAACGTGCATATGTCTCAAAGAATTCAACTATGGAGT
GGATTGACGGGAATATAGGGTCAAAAGTTACCATGAAGTATCCGTCTGTTTATCTTGCAGATGAGGGTGCAAAAGGGGAG
ATTCTCTCAGTTGCCTTTGCCGGTCCGGGGCAATATCAGGACGCCGGTGCTAAGGCCATACACATTGCACCCCGAACAAA
GTCAGCAATTGTTTCGAAATCTATTGCCAGAGGGGGAGGCCGCACTGCTTATCGAGGGGAAGTAAGGGTTGAAGAAGGCG
CAAAAGATTCAGCTAATTCTGTCCGATGTGATGCATTGTTAGTCGATACAATCTCAAGGTCTGATACATATCCAGCGATA
GACATAAGGAGGGATGATGCGCAGCTAGCCCACGAAGCTACCGTGTCAAAGGTCAATGAGGACCAGCTCTTTTATCTTAT
GAGTCGCGGTTTGGAAGAAGCTGAGTCTGTTGCGATGATAGTTCGGGGTTTTATTGATCCTATAGTGCGAGAGCTACCCA
TGGAATATGCAATGGAGCTCAATAAATTGATTGAAATGAGCATGGAAGGTGCAGTTGGCTAG

Upstream 100 bases:

>100_bases
GTTACTTCACGCGTTATTTGGATAGTAATTAATGAGTGTTCTAGAGCAAGCCGGATATATTTCAGATTTTGTTGGCCAGA
CTTTTCATTGGAGCGAATAA

Downstream 100 bases:

>100_bases
TCAATCGCCAACACAAACTCGGTCCGAGAGATTCTGTTCTGAAAATCCTAGTGATTTTCCGGAACCGAGCAATAGAGATC
TGGCCTGGAAATATGCCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSENLIANRPDLDSLGKYEYGWHDSDRAGSDARRGLSRDVVEEISETKGEPDWMRSMRLRALEIFYRKPMPNWGADLTGI
DFDQIKYFVRSTERQANSWEDLPEEIRNTYERLGIPDAERQRLVAGVAAQYESEVVYHQINAELERQGVVFLDTDTALKE
HPDILRKYFGSVIPAGDNKFAALNTAVWSGGSFVYVPEGVKVEIPLQAYFRINTENMGQFERTLIIADKNSYVHYVEGCT
APIYSSHSLHSAVVEILVKEGARVRYTTVQNWSTNVYNLVTKRAYVSKNSTMEWIDGNIGSKVTMKYPSVYLADEGAKGE
ILSVAFAGPGQYQDAGAKAIHIAPRTKSAIVSKSIARGGGRTAYRGEVRVEEGAKDSANSVRCDALLVDTISRSDTYPAI
DIRRDDAQLAHEATVSKVNEDQLFYLMSRGLEEAESVAMIVRGFIDPIVRELPMEYAMELNKLIEMSMEGAVG

Sequences:

>Translated_473_residues
MSENLIANRPDLDSLGKYEYGWHDSDRAGSDARRGLSRDVVEEISETKGEPDWMRSMRLRALEIFYRKPMPNWGADLTGI
DFDQIKYFVRSTERQANSWEDLPEEIRNTYERLGIPDAERQRLVAGVAAQYESEVVYHQINAELERQGVVFLDTDTALKE
HPDILRKYFGSVIPAGDNKFAALNTAVWSGGSFVYVPEGVKVEIPLQAYFRINTENMGQFERTLIIADKNSYVHYVEGCT
APIYSSHSLHSAVVEILVKEGARVRYTTVQNWSTNVYNLVTKRAYVSKNSTMEWIDGNIGSKVTMKYPSVYLADEGAKGE
ILSVAFAGPGQYQDAGAKAIHIAPRTKSAIVSKSIARGGGRTAYRGEVRVEEGAKDSANSVRCDALLVDTISRSDTYPAI
DIRRDDAQLAHEATVSKVNEDQLFYLMSRGLEEAESVAMIVRGFIDPIVRELPMEYAMELNKLIEMSMEGAVG
>Mature_472_residues
SENLIANRPDLDSLGKYEYGWHDSDRAGSDARRGLSRDVVEEISETKGEPDWMRSMRLRALEIFYRKPMPNWGADLTGID
FDQIKYFVRSTERQANSWEDLPEEIRNTYERLGIPDAERQRLVAGVAAQYESEVVYHQINAELERQGVVFLDTDTALKEH
PDILRKYFGSVIPAGDNKFAALNTAVWSGGSFVYVPEGVKVEIPLQAYFRINTENMGQFERTLIIADKNSYVHYVEGCTA
PIYSSHSLHSAVVEILVKEGARVRYTTVQNWSTNVYNLVTKRAYVSKNSTMEWIDGNIGSKVTMKYPSVYLADEGAKGEI
LSVAFAGPGQYQDAGAKAIHIAPRTKSAIVSKSIARGGGRTAYRGEVRVEEGAKDSANSVRCDALLVDTISRSDTYPAID
IRRDDAQLAHEATVSKVNEDQLFYLMSRGLEEAESVAMIVRGFIDPIVRELPMEYAMELNKLIEMSMEGAVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=464, Percent_Identity=39.2241379310345, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787971, Length=154, Percent_Identity=26.6233766233766, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 52975; Mature: 52844

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENLIANRPDLDSLGKYEYGWHDSDRAGSDARRGLSRDVVEEISETKGEPDWMRSMRLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
ALEIFYRKPMPNWGADLTGIDFDQIKYFVRSTERQANSWEDLPEEIRNTYERLGIPDAER
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHH
QRLVAGVAAQYESEVVYHQINAELERQGVVFLDTDTALKEHPDILRKYFGSVIPAGDNKF
HHHHHHHHHHHHHHHEEEHHCCHHHHCCEEEEECCCHHHCCHHHHHHHHCCEECCCCCCE
AALNTAVWSGGSFVYVPEGVKVEIPLQAYFRINTENMGQFERTLIIADKNSYVHYVEGCT
EEEEHEEECCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEEEEEECCCEEEEECCCC
APIYSSHSLHSAVVEILVKEGARVRYTTVQNWSTNVYNLVTKRAYVSKNSTMEWIDGNIG
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
SKVTMKYPSVYLADEGAKGEILSVAFAGPGQYQDAGAKAIHIAPRTKSAIVSKSIARGGG
CEEEEECCEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCC
RTAYRGEVRVEEGAKDSANSVRCDALLVDTISRSDTYPAIDIRRDDAQLAHEATVSKVNE
CCEEECCEEECCCCCCCCCCEEEEEEEEEHHCCCCCCCEEEEECCHHHHHHHHHHHHCCC
DQLFYLMSRGLEEAESVAMIVRGFIDPIVRELPMEYAMELNKLIEMSMEGAVG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SENLIANRPDLDSLGKYEYGWHDSDRAGSDARRGLSRDVVEEISETKGEPDWMRSMRLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
ALEIFYRKPMPNWGADLTGIDFDQIKYFVRSTERQANSWEDLPEEIRNTYERLGIPDAER
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHH
QRLVAGVAAQYESEVVYHQINAELERQGVVFLDTDTALKEHPDILRKYFGSVIPAGDNKF
HHHHHHHHHHHHHHHEEEHHCCHHHHCCEEEEECCCHHHCCHHHHHHHHCCEECCCCCCE
AALNTAVWSGGSFVYVPEGVKVEIPLQAYFRINTENMGQFERTLIIADKNSYVHYVEGCT
EEEEHEEECCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEEEEEECCCEEEEECCCC
APIYSSHSLHSAVVEILVKEGARVRYTTVQNWSTNVYNLVTKRAYVSKNSTMEWIDGNIG
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCC
SKVTMKYPSVYLADEGAKGEILSVAFAGPGQYQDAGAKAIHIAPRTKSAIVSKSIARGGG
CEEEEECCEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCC
RTAYRGEVRVEEGAKDSANSVRCDALLVDTISRSDTYPAIDIRRDDAQLAHEATVSKVNE
CCEEECCEEECCCCCCCCCCEEEEEEEEEHHCCCCCCCEEEEECCHHHHHHHHHHHHCCC
DQLFYLMSRGLEEAESVAMIVRGFIDPIVRELPMEYAMELNKLIEMSMEGAVG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]