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The map label for this gene is atpD

Identifier: 28572498

GI number: 28572498

Start: 374908

End: 376332

Strand: Direct

Name: atpD

Synonym: TW344

Alternate gene names: 28572498

Gene position: 374908-376332 (Clockwise)

Preceding gene: 28572497

Following gene: 28572499

Centisome position: 40.49

GC content: 46.74

Gene sequence:

>1425_bases
ATGACAGGGGATGCAGTTGGGCGGATAGTGCGGGTTACGGGCTCTGTCGTAGATGTGGAGTTTTCACGCAATAACCTTCC
TGGCGTTTTTAACGCCTTGAAGACCCGTGTAAACCGTTCTGGAAAAGAAATTGAGATAACCCTTGAAGTTGCTCAGCATC
TTGGTGACGACTTGGTCCGTACGGTTGCCATGCAATCTACTGATGGTCTAATAAGGGGTCAAGAGGTGCTTGATACCGGT
GGACATATCACTGTCCCTGTAGGTGATGCGACAAAGGGAAGGGTTTTTAACGTTGTTGGTGAGGTCTTAAACAGTAACGG
CGAAGATATCAAATTTGATGAGTATTGGTCTATACACCGCAAGCCGCCAGAATTTAGTCTTCTTGAAAGTAAGACTCAGC
TTTTTGAAACTGGCATTAAAGTTATTGATCTTCTAACCCCGTATGTTCAGGGCGGTAAAATCGGACTCTTTGGTGGTGCT
GGTGTTGGTAAAACTGTTCTTATTCAGGAAATGATACAAAGAGTGGCCCAGGATCATGGCGGTGTATCGGTTTTTGCCGG
GGTTGGTGAGCGTACGCGCGAGGGTAACGACCTGATTCGCGAGATGCAGGATGCTGGTGTTTTTGATAAAACCGCTCTTG
TTTTTGGACAAATGGATGAACCTCCCGGCACACGCCTTCGTGTCGCCCTAAGTGCCCTTACGATGGCAGAATACTTCCGA
GATGTCCAGAAGCAGGATGTCTTATTGTTCATAGATAACATTTTCCGTTTCACGCAAGCAGGATCAGAGGTGTCTACTTT
GCTTGGACGTATACCCTCGGCTGTTGGATATCAGCCAAATTTAGCTGATGAAATGGGTGTCTTGCAGGAGAGAATTACAT
CAACACGAGGTCACTCAATTACTTCTCTTCAGGCGATCTATGTGCCGGCAGATGATTATACGGACCCAGCCCCGGCAACA
ACTTTTGCTCATCTTGATGCGACAACTGAACTAAGTCGTGAGATTGCCTCAAAAGGCTTGTATCCTGCTGTTGACCCGCT
TGCGTCAACCAGTCGCATACTTGATCCAAAATACATTGGTAAGGATCATTACAGGGTCGCAGTTACAGTGAAACAGATTC
TGCAAAGAGATAAGGAGCTGCGGGAAATAATTGCAATTCTCGGGATTGATGAGCTATCAGAAGAGGACAGAGTTACAGTT
GCCCGCGCCAGGCGGATTGAGCAGTTCCTGAGTCAGAATACATATATGGCAAAGAAATTTACGGGTGTGGACGGATCAAC
TGTCCCGCTTCAGGAAACAATCGATGGATTTGATGCAATCTGCAGAGGTGACTGCGATCATATTCCAGAACAGGCCTTTT
TCAATGTCGGCGGACTTGAGGATGTTGAGCGCAAGTGGAGTAAGCTGCAAAAGGAATTAGGTTAA

Upstream 100 bases:

>100_bases
TCAGCAGATCTCTGAGATTATCGGAGGTGCTGGTGCCCTCGATTCAGGCTGAATGTTTCTGTGATTGTTTTGTATATTAG
GATGCGGATGATTGGAGATT

Downstream 100 bases:

>100_bases
ATTGGCCACCTTTGAAACGAAAGTTGTTTCTGCGAAGTCGTTTTCGCTAACATGCAGCGCAACTCTTGTTGTTGCGCGCA
CTCGCGCTGGAGAAATAGGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVRTVAMQSTDGLIRGQEVLDTG
GHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHRKPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGA
GVGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFR
DVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPAT
TFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIGKDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTV
ARARRIEQFLSQNTYMAKKFTGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG

Sequences:

>Translated_474_residues
MTGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVRTVAMQSTDGLIRGQEVLDTG
GHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHRKPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGA
GVGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFR
DVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPAT
TFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIGKDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTV
ARARRIEQFLSQNTYMAKKFTGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG
>Mature_473_residues
TGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVRTVAMQSTDGLIRGQEVLDTGG
HITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHRKPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAG
VGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFRD
VQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPATT
FAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIGKDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTVA
RARRIEQFLSQNTYMAKKFTGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=476, Percent_Identity=62.3949579831933, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI19913424, Length=332, Percent_Identity=28.6144578313253, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI19913426, Length=356, Percent_Identity=23.314606741573, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI19913428, Length=356, Percent_Identity=22.752808988764, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI50345984, Length=394, Percent_Identity=25.1269035532995, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4757810, Length=394, Percent_Identity=25.1269035532995, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1790170, Length=465, Percent_Identity=60.8602150537634, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1788251, Length=426, Percent_Identity=30.0469483568075, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790172, Length=320, Percent_Identity=25.9375, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=477, Percent_Identity=61.2159329140461, Blast_Score=568, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17565854, Length=339, Percent_Identity=29.2035398230088, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17510931, Length=354, Percent_Identity=22.5988700564972, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17570191, Length=354, Percent_Identity=22.5988700564972, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988080, Length=362, Percent_Identity=26.7955801104972, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=362, Percent_Identity=26.7955801104972, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988074, Length=291, Percent_Identity=26.1168384879725, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322581, Length=461, Percent_Identity=60.7375271149675, Blast_Score=566, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=356, Percent_Identity=25.2808988764045, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=369, Percent_Identity=24.6612466124661, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320016, Length=254, Percent_Identity=25.1968503937008, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24638766, Length=472, Percent_Identity=63.5593220338983, Blast_Score=580, Evalue=1e-166,
Organism=Drosophila melanogaster, GI28574560, Length=473, Percent_Identity=59.1966173361522, Blast_Score=533, Evalue=1e-151,
Organism=Drosophila melanogaster, GI20129479, Length=462, Percent_Identity=27.4891774891775, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24583992, Length=348, Percent_Identity=29.0229885057471, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583988, Length=346, Percent_Identity=28.0346820809249, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24583986, Length=346, Percent_Identity=28.0346820809249, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24583984, Length=346, Percent_Identity=28.0346820809249, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281361666, Length=357, Percent_Identity=24.0896358543417, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646341, Length=357, Percent_Identity=24.0896358543417, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136796, Length=357, Percent_Identity=24.0896358543417, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638768, Length=95, Percent_Identity=55.7894736842105, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658560, Length=362, Percent_Identity=26.2430939226519, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_TROW8 (Q83HY0)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789278.1
- ProteinModelPortal:   Q83HY0
- SMR:   Q83HY0
- STRING:   Q83HY0
- GeneID:   1064631
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW344
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   TWHI218496:TW0323-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 52087; Mature: 51956

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVR
CCCHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHCCHHHHH
TVAMQSTDGLIRGQEVLDTGGHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHR
HHHHHCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHCCC
KPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQDHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
GVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFR
CEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHH
DVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSI
HHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHCCCCCE
TSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIG
EEEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHCC
KDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTVARARRIEQFLSQNTYMAKKF
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCEEHHEE
TGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG
CCCCCCCCCHHHHHHHHHHHHCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVR
CCHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHCCHHHHH
TVAMQSTDGLIRGQEVLDTGGHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHR
HHHHHCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHCCC
KPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQDHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
GVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFR
CEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHH
DVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSI
HHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHCCCCCE
TSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIG
EEEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHCC
KDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTVARARRIEQFLSQNTYMAKKF
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCEEHHEE
TGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG
CCCCCCCCCHHHHHHHHHHHHCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12606174