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The map label for this gene is atpB [H]

Identifier: 28572492

GI number: 28572492

Start: 369786

End: 370601

Strand: Direct

Name: atpB [H]

Synonym: TW338

Alternate gene names: 28572492

Gene position: 369786-370601 (Clockwise)

Preceding gene: 28572491

Following gene: 28572493

Centisome position: 39.94

GC content: 44.36

Gene sequence:

>816_bases
GTGTCTATTGTGTTTTCAGGGGGTGGTTTGCTTCTTTCTGATTCGTGTCAGGCAGGAGAGTTTTGTGGACCCTCTGTTGA
GGAGTTTGCACCCTCTGCTCTTTTGTTTCACGGGACTTTTCTAGAGGTGAATCGGATTATTCTTATTCGGTTTCTGGCTG
TTGGTTTAATAATCGCTTTTTTTTGGCTCTCCCTCCGTAGGCCTAAGCCGGTTCCGGGAAAATTTCAGTCTCTTATTGAA
TTGTGTTTGGAATTTGTCCGTAAGAACATAGCTGAGGACATCCTTGGCAAAGATGCCCATCGATTTCTTCCTCTCTTGAC
CGGCATTTTCTTCCTCACTTTGTCTATGAACATAATGGGCATTATTCCTGGGCTCAATATTGCTGGCACATCTGTTATTG
GGCTCCCTCTGGTAATGGCCCTTGTTGCCTCTGTTTCATTTGTTTATGCGGGTTTTAAAAGGCACGGTTTCCGTTATATG
TCTATGACGCTTTTCCCCGCCGGTGTCCCACGCCCGCTGTATATTCTCGTTGCCCCAATAGAGTTCCTTTCTGTGTTTAT
CTTGAGGCCGATAACCTTGACCCTGAGGTTAACTATGAATATGATGGCCGGCCATCTTCTTTTGGTTCTTTGCTTCCTCG
CAACTGATTTTTTGTTCTTCACCGTTGGTGGGGCTTTCGCGGTTTTAGGTATTGGCACTTTATTGATCGGGCTTGCTTTT
ACCCTTTTTGAAATTGCAGTTTGCTTTTTACAGGCTTATATATTCACCCTTTTAACGGGGGTTTATATAGAGCTTTCACT
TGCTGATGAGCATTGA

Upstream 100 bases:

>100_bases
CGGATTTGCATTTTTTTTATGCACAACACTAATCTGCGTTGGAAGTCTCGTAATCGATACACTGCTTGTTCTTCGTAGTG
GTGTTTTTGATAGTATCTGA

Downstream 100 bases:

>100_bases
AATAGATGTTTTTGGAGAATAACGAAATGAATGGAGATTATGCATGGGTAGTGTTCTTGCTGAAGTAGCTGGCAGTCTTG
CATCTATTGGCTATGGACTT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSIVFSGGGLLLSDSCQAGEFCGPSVEEFAPSALLFHGTFLEVNRIILIRFLAVGLIIAFFWLSLRRPKPVPGKFQSLIE
LCLEFVRKNIAEDILGKDAHRFLPLLTGIFFLTLSMNIMGIIPGLNIAGTSVIGLPLVMALVASVSFVYAGFKRHGFRYM
SMTLFPAGVPRPLYILVAPIEFLSVFILRPITLTLRLTMNMMAGHLLLVLCFLATDFLFFTVGGAFAVLGIGTLLIGLAF
TLFEIAVCFLQAYIFTLLTGVYIELSLADEH

Sequences:

>Translated_271_residues
MSIVFSGGGLLLSDSCQAGEFCGPSVEEFAPSALLFHGTFLEVNRIILIRFLAVGLIIAFFWLSLRRPKPVPGKFQSLIE
LCLEFVRKNIAEDILGKDAHRFLPLLTGIFFLTLSMNIMGIIPGLNIAGTSVIGLPLVMALVASVSFVYAGFKRHGFRYM
SMTLFPAGVPRPLYILVAPIEFLSVFILRPITLTLRLTMNMMAGHLLLVLCFLATDFLFFTVGGAFAVLGIGTLLIGLAF
TLFEIAVCFLQAYIFTLLTGVYIELSLADEH
>Mature_270_residues
SIVFSGGGLLLSDSCQAGEFCGPSVEEFAPSALLFHGTFLEVNRIILIRFLAVGLIIAFFWLSLRRPKPVPGKFQSLIEL
CLEFVRKNIAEDILGKDAHRFLPLLTGIFFLTLSMNIMGIIPGLNIAGTSVIGLPLVMALVASVSFVYAGFKRHGFRYMS
MTLFPAGVPRPLYILVAPIEFLSVFILRPITLTLRLTMNMMAGHLLLVLCFLATDFLFFTVGGAFAVLGIGTLLIGLAFT
LFEIAVCFLQAYIFTLLTGVYIELSLADEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226527, Length=212, Percent_Identity=28.3018867924528, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29710; Mature: 29579

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVFSGGGLLLSDSCQAGEFCGPSVEEFAPSALLFHGTFLEVNRIILIRFLAVGLIIAF
CEEEEECCCEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWLSLRRPKPVPGKFQSLIELCLEFVRKNIAEDILGKDAHRFLPLLTGIFFLTLSMNIMG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IIPGLNIAGTSVIGLPLVMALVASVSFVYAGFKRHGFRYMSMTLFPAGVPRPLYILVAPI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEHH
EFLSVFILRPITLTLRLTMNMMAGHLLLVLCFLATDFLFFTVGGAFAVLGIGTLLIGLAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFEIAVCFLQAYIFTLLTGVYIELSLADEH
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure 
SIVFSGGGLLLSDSCQAGEFCGPSVEEFAPSALLFHGTFLEVNRIILIRFLAVGLIIAF
EEEEECCCEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWLSLRRPKPVPGKFQSLIELCLEFVRKNIAEDILGKDAHRFLPLLTGIFFLTLSMNIMG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IIPGLNIAGTSVIGLPLVMALVASVSFVYAGFKRHGFRYMSMTLFPAGVPRPLYILVAPI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEHH
EFLSVFILRPITLTLRLTMNMMAGHLLLVLCFLATDFLFFTVGGAFAVLGIGTLLIGLAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFEIAVCFLQAYIFTLLTGVYIELSLADEH
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA