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The map label for this gene is xerC [H]

Identifier: 28572470

GI number: 28572470

Start: 348498

End: 349418

Strand: Direct

Name: xerC [H]

Synonym: TW315

Alternate gene names: 28572470

Gene position: 348498-349418 (Clockwise)

Preceding gene: 28572469

Following gene: 28572471

Centisome position: 37.64

GC content: 47.01

Gene sequence:

>921_bases
GTGTGCCCCTGCGGCGACACCCTCAACGAGGGGTTTTGCTGTTTAATACGCGAGTTTATTATTTACCTGGAAAATGTTAG
GGGCTACAGTTCACACACTTGTCGGGCATATTATCGTGACCTGATGTGCTTTGGTGAATACATTATTACCCATGACTCTC
GCGAGAATGTAAAGTCCTTACGAGATGTGTCAATTCAGGATTTACGCTCGTGGCTATACAGTCAAAGCCATAAGTCTGCA
AGGTCTATCAGACGGGCAGTCTCTTCTTTGAAAAGCTTTTTTAGATGGGCATATGACAGAAAGATCACTGCCCAAAACAC
TGCTGCTGCCCTAAGGGCACCGAAGTCCACTTCGCAGCTACCCTCTGTTTTATCGGAAAAAAGGATTGCACAGATCCTGG
GTAATTTCTCACATACGGTCCCAGTAATACAGTTACGTAATACGGCAATTTTTGAGCTGTTATATGCATCGGCGATTAGA
GTGTCTGAGTTGGTCTCTCTAGATCTTGACAGTATTGACCACGATCTGTGCACCGTCAGGGTTGATGGTAAAAATGGTAA
ACAGCGGGTTGTGTTGTTTGGCAAGCCCGCATCACATGCTCTGGATTTATATCTGAATATGCGCCACACCCTATTATCTG
ACAGATCAAGTAAAGCCCTATTTTTAGGTTCCCGTGGTCGTCGCATAAATCCACGTGTTGTGTATCGACTGGTATCAGAA
CTCCTCGAGATGCCCAAGGGCCCGCGGGGCCCGCACGTTCTTAGACACTCTGCAGCGACCCATATGCTGGACAATGGGGC
TGATCTCAGGAGCCTTCAGGAAATCCTGGGTCATAGTAGCCTCAGTACAACCCAAATTTACACACATGTTTCTCTAGAGC
GCTTAATAAGCAGTTACAACCAGGCACATCCAAGGGCCTGA

Upstream 100 bases:

>100_bases
TGAACTGTCGGGGCAGGTGATCCGATCAGGTTCCGGCTGGCGCCTATCAGGTAGGCTTAGATGAAAATTTATGTTGGATA
AGGGCTCTCTCAAGAGATCA

Downstream 100 bases:

>100_bases
ATTCGCGCATTGTATTATGTTTACGCCACATTGCCTACATGTCAAGTCCATGAGTTTGTGTCGCTTTCGCAGGAATGCCC
CGGGTGTACAGTCCGGAATG

Product: DNA recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MCPCGDTLNEGFCCLIREFIIYLENVRGYSSHTCRAYYRDLMCFGEYIITHDSRENVKSLRDVSIQDLRSWLYSQSHKSA
RSIRRAVSSLKSFFRWAYDRKITAQNTAAALRAPKSTSQLPSVLSEKRIAQILGNFSHTVPVIQLRNTAIFELLYASAIR
VSELVSLDLDSIDHDLCTVRVDGKNGKQRVVLFGKPASHALDLYLNMRHTLLSDRSSKALFLGSRGRRINPRVVYRLVSE
LLEMPKGPRGPHVLRHSAATHMLDNGADLRSLQEILGHSSLSTTQIYTHVSLERLISSYNQAHPRA

Sequences:

>Translated_306_residues
MCPCGDTLNEGFCCLIREFIIYLENVRGYSSHTCRAYYRDLMCFGEYIITHDSRENVKSLRDVSIQDLRSWLYSQSHKSA
RSIRRAVSSLKSFFRWAYDRKITAQNTAAALRAPKSTSQLPSVLSEKRIAQILGNFSHTVPVIQLRNTAIFELLYASAIR
VSELVSLDLDSIDHDLCTVRVDGKNGKQRVVLFGKPASHALDLYLNMRHTLLSDRSSKALFLGSRGRRINPRVVYRLVSE
LLEMPKGPRGPHVLRHSAATHMLDNGADLRSLQEILGHSSLSTTQIYTHVSLERLISSYNQAHPRA
>Mature_306_residues
MCPCGDTLNEGFCCLIREFIIYLENVRGYSSHTCRAYYRDLMCFGEYIITHDSRENVKSLRDVSIQDLRSWLYSQSHKSA
RSIRRAVSSLKSFFRWAYDRKITAQNTAAALRAPKSTSQLPSVLSEKRIAQILGNFSHTVPVIQLRNTAIFELLYASAIR
VSELVSLDLDSIDHDLCTVRVDGKNGKQRVVLFGKPASHALDLYLNMRHTLLSDRSSKALFLGSRGRRINPRVVYRLVSE
LLEMPKGPRGPHVLRHSAATHMLDNGADLRSLQEILGHSSLSTTQIYTHVSLERLISSYNQAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=35.5932203389831, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=34.4594594594595, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34676; Mature: 34676

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCPCGDTLNEGFCCLIREFIIYLENVRGYSSHTCRAYYRDLMCFGEYIITHDSRENVKSL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHH
RDVSIQDLRSWLYSQSHKSARSIRRAVSSLKSFFRWAYDRKITAQNTAAALRAPKSTSQL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHH
PSVLSEKRIAQILGNFSHTVPVIQLRNTAIFELLYASAIRVSELVSLDLDSIDHDLCTVR
HHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDGKNGKQRVVLFGKPASHALDLYLNMRHTLLSDRSSKALFLGSRGRRINPRVVYRLVSE
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHH
LLEMPKGPRGPHVLRHSAATHMLDNGADLRSLQEILGHSSLSTTQIYTHVSLERLISSYN
HHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QAHPRA
HCCCCC
>Mature Secondary Structure
MCPCGDTLNEGFCCLIREFIIYLENVRGYSSHTCRAYYRDLMCFGEYIITHDSRENVKSL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHH
RDVSIQDLRSWLYSQSHKSARSIRRAVSSLKSFFRWAYDRKITAQNTAAALRAPKSTSQL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHH
PSVLSEKRIAQILGNFSHTVPVIQLRNTAIFELLYASAIRVSELVSLDLDSIDHDLCTVR
HHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VDGKNGKQRVVLFGKPASHALDLYLNMRHTLLSDRSSKALFLGSRGRRINPRVVYRLVSE
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHH
LLEMPKGPRGPHVLRHSAATHMLDNGADLRSLQEILGHSSLSTTQIYTHVSLERLISSYN
HHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QAHPRA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA