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The map label for this gene is ideR [H]

Identifier: 28572287

GI number: 28572287

Start: 130688

End: 131341

Strand: Direct

Name: ideR [H]

Synonym: TW124

Alternate gene names: 28572287

Gene position: 130688-131341 (Clockwise)

Preceding gene: 28572286

Following gene: 28572288

Centisome position: 14.11

GC content: 44.8

Gene sequence:

>654_bases
ATGTACTTGAGGACAATTGTCAATCTCGAAGAAGAAGGTATTAGTCCGATAATAAAGGCCAGGATTTCTGAGCGTATCGG
ACACACGGCGCCAACTGTTTTTCAGACGATTGCGAGAATGCAGCGCGATGGGTTACTTGTTGTTTCGTCGAACAAAAGCC
TGATCCTTACATCAAAGGGAAGGAAAATCGCGCTTTCCGTTGTACGCAAACATCGCCTGGCGGAGGTTCTTCTACATGAC
GTGGTAGGCCTTGAATGGGAGCATATTCATTTGGAAGCTTGTCGCCTTGAACACGTTATGAGTGATCACCTCGAAGAGCA
CCTGCGAAGAATATTAAATAATCCATCTTTTACCACATACGGAACACCAATTCCTCCAGCTGATAGTGATTTTGTAGAAC
CATTTCGTGATGTGATTTCTCTTTCACGGGCCGTTATTCGACAAAAAGCACGAAAACTGTCAGTGCGGTGTTTAGGTGAA
ATTGCGCAGCAGGACACTATTCTGCTATCTCAGCTTTCAAAGGCCGGATTGCGCCCGGGGGGATTGGGAAGTTTTATGGA
TTCTCAGAACGGCATTTTGTCATGGACAAATTCGGGGAATAAGTTCATTATCTCGCATTACATCGCGGAGTGCATATTTG
TAAATCAAAACTGA

Upstream 100 bases:

>100_bases
AGCAGCTCTCTAAATGTCGAACCGAATAAACAGCCGATTACGCGGAGCTCTTTGCGGGAAGTAGTCTTTACGGGTGAATG
ATCTAGTTGATACAACTGAA

Downstream 100 bases:

>100_bases
CGCATGTGCAGGCCCAACGAATAAAGGGACCTGGACATAAAGAGACCTAGGGTTGCAGTGTAACTGTAATAATGTATGTA
ATTGTAATAATGTAACTGCA

Product: iron-dependent repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MYLRTIVNLEEEGISPIIKARISERIGHTAPTVFQTIARMQRDGLLVVSSNKSLILTSKGRKIALSVVRKHRLAEVLLHD
VVGLEWEHIHLEACRLEHVMSDHLEEHLRRILNNPSFTTYGTPIPPADSDFVEPFRDVISLSRAVIRQKARKLSVRCLGE
IAQQDTILLSQLSKAGLRPGGLGSFMDSQNGILSWTNSGNKFIISHYIAECIFVNQN

Sequences:

>Translated_217_residues
MYLRTIVNLEEEGISPIIKARISERIGHTAPTVFQTIARMQRDGLLVVSSNKSLILTSKGRKIALSVVRKHRLAEVLLHD
VVGLEWEHIHLEACRLEHVMSDHLEEHLRRILNNPSFTTYGTPIPPADSDFVEPFRDVISLSRAVIRQKARKLSVRCLGE
IAQQDTILLSQLSKAGLRPGGLGSFMDSQNGILSWTNSGNKFIISHYIAECIFVNQN
>Mature_217_residues
MYLRTIVNLEEEGISPIIKARISERIGHTAPTVFQTIARMQRDGLLVVSSNKSLILTSKGRKIALSVVRKHRLAEVLLHD
VVGLEWEHIHLEACRLEHVMSDHLEEHLRRILNNPSFTTYGTPIPPADSDFVEPFRDVISLSRAVIRQKARKLSVRCLGE
IAQQDTILLSQLSKAGLRPGGLGSFMDSQNGILSWTNSGNKFIISHYIAECIFVNQN

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 24385; Mature: 24385

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLRTIVNLEEEGISPIIKARISERIGHTAPTVFQTIARMQRDGLLVVSSNKSLILTSKG
CCHHHEECCCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCEEEEECCC
RKIALSVVRKHRLAEVLLHDVVGLEWEHIHLEACRLEHVMSDHLEEHLRRILNNPSFTTY
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTPIPPADSDFVEPFRDVISLSRAVIRQKARKLSVRCLGEIAQQDTILLSQLSKAGLRPG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLGSFMDSQNGILSWTNSGNKFIISHYIAECIFVNQN
CCCCHHCCCCCEEEEECCCCEEHHHHHHHHHHEECCC
>Mature Secondary Structure
MYLRTIVNLEEEGISPIIKARISERIGHTAPTVFQTIARMQRDGLLVVSSNKSLILTSKG
CCHHHEECCCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCEEEEECCC
RKIALSVVRKHRLAEVLLHDVVGLEWEHIHLEACRLEHVMSDHLEEHLRRILNNPSFTTY
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTPIPPADSDFVEPFRDVISLSRAVIRQKARKLSVRCLGEIAQQDTILLSQLSKAGLRPG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLGSFMDSQNGILSWTNSGNKFIISHYIAECIFVNQN
CCCCHHCCCCCEEEEECCCCEEHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]