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The map label for this gene is fprA [H]

Identifier: 28572235

GI number: 28572235

Start: 55141

End: 56484

Strand: Direct

Name: fprA [H]

Synonym: TW065

Alternate gene names: 28572235

Gene position: 55141-56484 (Clockwise)

Preceding gene: 28572234

Following gene: 28572241

Centisome position: 5.96

GC content: 48.14

Gene sequence:

>1344_bases
TTGGCGAGGATTGCGGTAGTAGGTGCAGGTCCAGCGGGGATATATTCTGCCAATCTTCTTCTTGCCGATGAATCCGTTGA
GCGCGTTGATGTTTTTGAGGCATTACCAGCGCCTTATGGCCTTGTAAGGTATGGTGTTGCACCTGATCATCCGAGGATAA
AGAGTGTTGTAAGCACCCTCAGTGACATGTTAGAGACACCCCGTATGCGCCTTTTTTGCGGTGTGCATTTCGGGCAACAT
CTTTCTTTAGAGGATATAAAACAACGGTACAATGCAGTTATTTTTGCAACAGGCGCCCTCCGTGGGGCTAGACTCGATAT
TCCGGGAATTGATGCCAGGAATAGCTTTTCTGCGGCTGACTTTGTTGCCTGGTATGACGGGCATCCGGATTACCCACGGA
CATGGCCTTTGTCAGCAAAATCAGTTGGCATAATCGGTAACGGCAATGTTGCGCTGGATATTGCGCGAATTCTAGTAAAA
CAGCCTGAAGAACTAGAAACAACCGAAATACCCGACAATGTCTATGAAGATTTGAAGAGTTCTGCATTGTCTGACGTACA
CATATTTGGCCGTCGTGGGCCTTTTGACGTAAAGTTTACCCCCCTCGAACTCAGAGAGCTCGGCGAAGTAAACGGTGTGG
ATATTGTTCTTAATGAAGATGATTTTCAGGTAAAGCCTGATCGCCTGGTCAAGCAAATGATCATAATCGATCGTGTCTTT
TCCTCATGGAGGGCTCGCTCCGGTACATCCTCAACCAGGCGATTGCACTTTCACTTTTACTCGGTTCCCAAGCGGGTTGT
TGTTCGGGATAATTGCGTTTCTGGACTTGAGTACCAACAGCTGCGCCCCACGATAGATGCTTGCGATTGTGTTGCGCCCC
CGCGTGATAGTGACACGCGTCATGAGGTGGTAGAGCTTGATGCGCTTTATACGGCAATTGGATATTATGGCTCACCCCTT
TCCGACTTACCTTTTGATGATATTAGTGGCATTATTCCAAATGACCGCGGCAGGGTAATTATCGAGGGTAAGCCACTTAG
GGGATGTTACGTAACGGGCTGGATAAAGCGGGGCCCTGTTGGACTGATTGGTCATACAAAGAGTGATGCCATCGAGACAA
TAGTCAGTATGCGGCAGGATAAAACTGCCTGGTGGAAGCCAGATACTGACTCTGATATATCAGACCTATTGGGTAGCAGG
GGTGTGAACTTCACGGGTGTTAGCGGTTGGCGCAAGCTTGATGCGCACGAAATATATCTCGGCAGTCTCTCAGGTAAAAC
ACGTAAAAAGGTAGTTCCACGGGAAGAAATGTATTACATTTCTTCCCGTGGAAGCCCTTCGTAA

Upstream 100 bases:

>100_bases
TGCGTTGAAAAAACTTCCTGAATGTGCCCCTCGTGATGCACTTTTGGCGTTTGTCGAAACGGTTGTTTCTCGTGAGTTTT
AGAGAATAGAGGTAAGGGTT

Downstream 100 bases:

>100_bases
AAGAGGCAATGCCCCAGGATGATATGATGCCCTGATACTGTCTTGTGATACCGTCTTGTTCCGTACGCCTGTCTCGTACC
TCTATAGAGCGCTTTTCTGT

Product: ferredoxin/ferredoxin-NADP reductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MARIAVVGAGPAGIYSANLLLADESVERVDVFEALPAPYGLVRYGVAPDHPRIKSVVSTLSDMLETPRMRLFCGVHFGQH
LSLEDIKQRYNAVIFATGALRGARLDIPGIDARNSFSAADFVAWYDGHPDYPRTWPLSAKSVGIIGNGNVALDIARILVK
QPEELETTEIPDNVYEDLKSSALSDVHIFGRRGPFDVKFTPLELRELGEVNGVDIVLNEDDFQVKPDRLVKQMIIIDRVF
SSWRARSGTSSTRRLHFHFYSVPKRVVVRDNCVSGLEYQQLRPTIDACDCVAPPRDSDTRHEVVELDALYTAIGYYGSPL
SDLPFDDISGIIPNDRGRVIIEGKPLRGCYVTGWIKRGPVGLIGHTKSDAIETIVSMRQDKTAWWKPDTDSDISDLLGSR
GVNFTGVSGWRKLDAHEIYLGSLSGKTRKKVVPREEMYYISSRGSPS

Sequences:

>Translated_447_residues
MARIAVVGAGPAGIYSANLLLADESVERVDVFEALPAPYGLVRYGVAPDHPRIKSVVSTLSDMLETPRMRLFCGVHFGQH
LSLEDIKQRYNAVIFATGALRGARLDIPGIDARNSFSAADFVAWYDGHPDYPRTWPLSAKSVGIIGNGNVALDIARILVK
QPEELETTEIPDNVYEDLKSSALSDVHIFGRRGPFDVKFTPLELRELGEVNGVDIVLNEDDFQVKPDRLVKQMIIIDRVF
SSWRARSGTSSTRRLHFHFYSVPKRVVVRDNCVSGLEYQQLRPTIDACDCVAPPRDSDTRHEVVELDALYTAIGYYGSPL
SDLPFDDISGIIPNDRGRVIIEGKPLRGCYVTGWIKRGPVGLIGHTKSDAIETIVSMRQDKTAWWKPDTDSDISDLLGSR
GVNFTGVSGWRKLDAHEIYLGSLSGKTRKKVVPREEMYYISSRGSPS
>Mature_446_residues
ARIAVVGAGPAGIYSANLLLADESVERVDVFEALPAPYGLVRYGVAPDHPRIKSVVSTLSDMLETPRMRLFCGVHFGQHL
SLEDIKQRYNAVIFATGALRGARLDIPGIDARNSFSAADFVAWYDGHPDYPRTWPLSAKSVGIIGNGNVALDIARILVKQ
PEELETTEIPDNVYEDLKSSALSDVHIFGRRGPFDVKFTPLELRELGEVNGVDIVLNEDDFQVKPDRLVKQMIIIDRVFS
SWRARSGTSSTRRLHFHFYSVPKRVVVRDNCVSGLEYQQLRPTIDACDCVAPPRDSDTRHEVVELDALYTAIGYYGSPLS
DLPFDDISGIIPNDRGRVIIEGKPLRGCYVTGWIKRGPVGLIGHTKSDAIETIVSMRQDKTAWWKPDTDSDISDLLGSRG
VNFTGVSGWRKLDAHEIYLGSLSGKTRKKVVPREEMYYISSRGSPS

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=462, Percent_Identity=34.4155844155844, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI111118983, Length=468, Percent_Identity=33.974358974359, Blast_Score=228, Evalue=1e-59,
Organism=Escherichia coli, GI87082180, Length=165, Percent_Identity=28.4848484848485, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=441, Percent_Identity=33.7868480725624, Blast_Score=228, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6320584, Length=478, Percent_Identity=29.4979079497908, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI17137178, Length=454, Percent_Identity=33.920704845815, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 49634; Mature: 49503

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIAVVGAGPAGIYSANLLLADESVERVDVFEALPAPYGLVRYGVAPDHPRIKSVVSTL
CCEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHH
SDMLETPRMRLFCGVHFGQHLSLEDIKQRYNAVIFATGALRGARLDIPGIDARNSFSAAD
HHHHHCCCEEEEEEECCCCCCCHHHHHHHHCEEEEEECCCCCCEECCCCCCCCCCCCHHH
FVAWYDGHPDYPRTWPLSAKSVGIIGNGNVALDIARILVKQPEELETTEIPDNVYEDLKS
EEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SALSDVHIFGRRGPFDVKFTPLELRELGEVNGVDIVLNEDDFQVKPDRLVKQMIIIDRVF
HHCCCEEEECCCCCCCEEECHHHHHHCCCCCCEEEEECCCCCEECHHHHHHHHHHHHHHH
SSWRARSGTSSTRRLHFHFYSVPKRVVVRDNCVSGLEYQQLRPTIDACDCVAPPRDSDTR
HHHHCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHCCCHHHHHCCCCCCCCCCH
HEVVELDALYTAIGYYGSPLSDLPFDDISGIIPNDRGRVIIEGKPLRGCYVTGWIKRGPV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCE
GLIGHTKSDAIETIVSMRQDKTAWWKPDTDSDISDLLGSRGVNFTGVSGWRKLDAHEIYL
EEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCEECCCEEEEE
GSLSGKTRKKVVPREEMYYISSRGSPS
ECCCCCHHHCCCCHHHEEEEECCCCCC
>Mature Secondary Structure 
ARIAVVGAGPAGIYSANLLLADESVERVDVFEALPAPYGLVRYGVAPDHPRIKSVVSTL
CEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHH
SDMLETPRMRLFCGVHFGQHLSLEDIKQRYNAVIFATGALRGARLDIPGIDARNSFSAAD
HHHHHCCCEEEEEEECCCCCCCHHHHHHHHCEEEEEECCCCCCEECCCCCCCCCCCCHHH
FVAWYDGHPDYPRTWPLSAKSVGIIGNGNVALDIARILVKQPEELETTEIPDNVYEDLKS
EEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SALSDVHIFGRRGPFDVKFTPLELRELGEVNGVDIVLNEDDFQVKPDRLVKQMIIIDRVF
HHCCCEEEECCCCCCCEEECHHHHHHCCCCCCEEEEECCCCCEECHHHHHHHHHHHHHHH
SSWRARSGTSSTRRLHFHFYSVPKRVVVRDNCVSGLEYQQLRPTIDACDCVAPPRDSDTR
HHHHCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHCCCHHHHHCCCCCCCCCCH
HEVVELDALYTAIGYYGSPLSDLPFDDISGIIPNDRGRVIIEGKPLRGCYVTGWIKRGPV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCE
GLIGHTKSDAIETIVSMRQDKTAWWKPDTDSDISDLLGSRGVNFTGVSGWRKLDAHEIYL
EEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCEECCCEEEEE
GSLSGKTRKKVVPREEMYYISSRGSPS
ECCCCCHHHCCCCHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]