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The map label for this gene is uvrA3 [H]

Identifier: 28379367

GI number: 28379367

Start: 2591591

End: 2594098

Strand: Direct

Name: uvrA3 [H]

Synonym: lp_2915

Alternate gene names: 28379367

Gene position: 2591591-2594098 (Clockwise)

Preceding gene: 28379356

Following gene: 28379369

Centisome position: 78.34

GC content: 50.96

Gene sequence:

>2508_bases
ATGCCACAAACCACGTTACCGACTCACATTCAAGTGCGAGGCGCACACGTCAATAATTTAAAAAATATCGATATCGACAT
TCCACTCAACGAATTTGTTGCGATTACTGGTCGCAGTGGGTCCGGTAAGTCATCACTCGCAATGGGCGTCCTGTACGCTG
AGGGGGCCCGCCGCTACTTAAACGCCCTGTCAACCTTTACCCGCCGCCGAATCAATCAGGTCGGCAAAGCCAGTGTTGAT
TCAGTACAATACTTACCATCTGCATTAGCGCTACGCCAACGCCCCCAGGTTCCCGGCGTCCGTTCAACCGTCGGCACCAT
GTCTGAAAGCTTAAATATCTTAAGGCTAGCCTTCTCACGACTCAGCTCAGCAGTTTGCCCCAATGGTCACCGCATGCCAC
CAACGCTCGATGTGGCTGAAAATGATGGTTACGTCACCTGTCCGACTTGTGGCGCCAAATTCAGAGCGCCCGGCGCCGAA
GATTTCGCCTTCAATTCAGGTGGGGCCTGTCCGACTTGCGGTGGCCTAGGCCAAGTTCGCCAAATTGACCCGGCACTCAT
TATTGCTGATGAAAATCAAACTATCGAAGAAGGGGCCGTTGCTTCTTGGCACCTGCCTGGACGTAACTTTATGCCGATCG
TTGCACGCGAAATTGGGATTCCCATCGATATTCCGTATAAAGACCTTAGTGAAGCCGATAAAACACGCGTATTGCATGGT
CCTAAGCAAACCGTTGCCATCAACATTCCAAGCGCTAAAGGTAAAATCTTTCACATGGACAACGCTGTCTACGAGAACGC
CTTTGCCGCCGTTGAAGATAGTATGGCGACGACCAAAAATGAACGGGCAATTAATCGGCTGAATCGCTTTTACAAGTTTG
ATACTTGCCCAGATTGTCACGGATCACGCTTCAATCCTCAGTTGTTTAACTACGAATTAAATGGTCAAAACATTGCGACG
GTTAGTGATATGACTGTCGCCGCCTTGCATGATTTTGCGACCACGATTGTCCCGTGGCTACCTACTAAGATGCATCATCT
TGGACAATCCCTTGTTGATGAATTGCTACTCAGCCTGCAACCCATGGAAGAACTTGGACTCGACTACCTCACACTCAGTC
GTCCCGGTGCGACCCTGTCAACTGGTGAATTACAACGCATTCAGCTCGGACGCACTCTGCGTAGCGCCACGACTGGCGTG
TTATATGTCCTTGATGAACCTTCCGTTGGACTTCATCCAGCTAACGTGGCGGGCCTAATCAAAGCTTTCCGCGGGCTAGT
CGCCCAAGGAAATTCCGTCGTGGTGGTTGACCACGACACTAGTATTATCAGTGCAGCTGATGATGTTATTGAGATTGGTC
CGGGGGCTGGTAAGCACGGCGGTACCGTTGTCGGACAAGGCACTGTCGCAGCCATCAAGCGGGACAAAAAGTCCTTAATT
GCGCCATTTCTCACCGGTACTGCCACTCTGCGTGAACGCCCCGTATTAACCGACGATGCGCTCTGGAAAAAGGGGGCCCT
TGCTATTGAGGTGGCTCATCACTTTAACATCCAAGACATTACGGCGCGCATTCCCAAAAACCGTTTCACGACCGTCACGG
GTATGAGCGGCGCTGGTAAAACGACTCTGGTACTAGATAGTTTGATTCCAGCACTGATTGCCACAGCTAAAAAGCGACCA
CTTCCAACCCACGTTAAGGCCTTTGACAATGGTCACATTCGGCACGTTGTTACCGTCGACTCAGTGCCCGTTGGTAAGAA
TGTACGGTCAACGGTCGCCACTTATACCAACATTCTCGACCATCTACGCCAATTATTCGCCGCTACCCCAGCAGCACAAG
CAAACAGTTGGACCGCTAGCCAATTTTCATATAACGTCGCTGCGGGTGCTTGCCCAACTTGTGGTGGTACGGGCCAAATC
TCTTTAGATGTGCAATACTTGCCAGACATTACCGAAGTCTGCCCCCAATGCCACGGCAAGCGCTACAATAAACAGACGCT
GACTGTCAAATGGCATGGCTATTCGATTGCGGATATTTTAGATCTTGCGGTTGACGAGGCCCTACCAATTTTCAAAGTGC
AATCCGCCATCGCTAATACACTCCAGATCCTGCATGATATGGGACTAGGCTACTTACTATTAGGTGAAAGTACGCCGGCA
CTCTCGGGTGGCGAAGCTCAGCGCCTGAAGCTCACCTCCCGCATTGGCAAACGCCAAACGGGAACGCTCTTTGTCTTCGA
TGAGCCTTCAGTCGGTTTGCACCCGCTCGACATTCAGCAACTCGTCAAAGTCTTTGACCAACTGATTCAGCAAGGGGCAA
CCGTCATTGCCATCGAACACGATCTCGACGTAATCGCCAACGCTGATTACGTTATCGATATGGGACCCGCGGGCGGTATC
AACGGTGGTAACATTGTCGCCACCGGTACCCCATTGGCCGTTAGTCAAAATCCAACTAGTGTAACAGGGCAATATTTGAA
GACGCATTTGGCCCTATTCCACGTTTAA

Upstream 100 bases:

>100_bases
TACTCCCCCGGTCGTGGGGCGCGAGATACTGCCACCGCTTTCTTAGGCAAAGCCGTCCTTTTGTTGTAGCATATAAAGTG
ACACGAAAGGGGTTTTAGTC

Downstream 100 bases:

>100_bases
CCAATGAACTGCTGACCGACCTCATTCATCACAGCAGTCTGATCGAATATTTAATCAAAAAGCGTGTCCAACCCCCAGCT
AGTCAACTTGCTAGGGGTTA

Product: excinuclease ABC, subunit A

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 835; Mature: 834

Protein sequence:

>835_residues
MPQTTLPTHIQVRGAHVNNLKNIDIDIPLNEFVAITGRSGSGKSSLAMGVLYAEGARRYLNALSTFTRRRINQVGKASVD
SVQYLPSALALRQRPQVPGVRSTVGTMSESLNILRLAFSRLSSAVCPNGHRMPPTLDVAENDGYVTCPTCGAKFRAPGAE
DFAFNSGGACPTCGGLGQVRQIDPALIIADENQTIEEGAVASWHLPGRNFMPIVAREIGIPIDIPYKDLSEADKTRVLHG
PKQTVAINIPSAKGKIFHMDNAVYENAFAAVEDSMATTKNERAINRLNRFYKFDTCPDCHGSRFNPQLFNYELNGQNIAT
VSDMTVAALHDFATTIVPWLPTKMHHLGQSLVDELLLSLQPMEELGLDYLTLSRPGATLSTGELQRIQLGRTLRSATTGV
LYVLDEPSVGLHPANVAGLIKAFRGLVAQGNSVVVVDHDTSIISAADDVIEIGPGAGKHGGTVVGQGTVAAIKRDKKSLI
APFLTGTATLRERPVLTDDALWKKGALAIEVAHHFNIQDITARIPKNRFTTVTGMSGAGKTTLVLDSLIPALIATAKKRP
LPTHVKAFDNGHIRHVVTVDSVPVGKNVRSTVATYTNILDHLRQLFAATPAAQANSWTASQFSYNVAAGACPTCGGTGQI
SLDVQYLPDITEVCPQCHGKRYNKQTLTVKWHGYSIADILDLAVDEALPIFKVQSAIANTLQILHDMGLGYLLLGESTPA
LSGGEAQRLKLTSRIGKRQTGTLFVFDEPSVGLHPLDIQQLVKVFDQLIQQGATVIAIEHDLDVIANADYVIDMGPAGGI
NGGNIVATGTPLAVSQNPTSVTGQYLKTHLALFHV

Sequences:

>Translated_835_residues
MPQTTLPTHIQVRGAHVNNLKNIDIDIPLNEFVAITGRSGSGKSSLAMGVLYAEGARRYLNALSTFTRRRINQVGKASVD
SVQYLPSALALRQRPQVPGVRSTVGTMSESLNILRLAFSRLSSAVCPNGHRMPPTLDVAENDGYVTCPTCGAKFRAPGAE
DFAFNSGGACPTCGGLGQVRQIDPALIIADENQTIEEGAVASWHLPGRNFMPIVAREIGIPIDIPYKDLSEADKTRVLHG
PKQTVAINIPSAKGKIFHMDNAVYENAFAAVEDSMATTKNERAINRLNRFYKFDTCPDCHGSRFNPQLFNYELNGQNIAT
VSDMTVAALHDFATTIVPWLPTKMHHLGQSLVDELLLSLQPMEELGLDYLTLSRPGATLSTGELQRIQLGRTLRSATTGV
LYVLDEPSVGLHPANVAGLIKAFRGLVAQGNSVVVVDHDTSIISAADDVIEIGPGAGKHGGTVVGQGTVAAIKRDKKSLI
APFLTGTATLRERPVLTDDALWKKGALAIEVAHHFNIQDITARIPKNRFTTVTGMSGAGKTTLVLDSLIPALIATAKKRP
LPTHVKAFDNGHIRHVVTVDSVPVGKNVRSTVATYTNILDHLRQLFAATPAAQANSWTASQFSYNVAAGACPTCGGTGQI
SLDVQYLPDITEVCPQCHGKRYNKQTLTVKWHGYSIADILDLAVDEALPIFKVQSAIANTLQILHDMGLGYLLLGESTPA
LSGGEAQRLKLTSRIGKRQTGTLFVFDEPSVGLHPLDIQQLVKVFDQLIQQGATVIAIEHDLDVIANADYVIDMGPAGGI
NGGNIVATGTPLAVSQNPTSVTGQYLKTHLALFHV
>Mature_834_residues
PQTTLPTHIQVRGAHVNNLKNIDIDIPLNEFVAITGRSGSGKSSLAMGVLYAEGARRYLNALSTFTRRRINQVGKASVDS
VQYLPSALALRQRPQVPGVRSTVGTMSESLNILRLAFSRLSSAVCPNGHRMPPTLDVAENDGYVTCPTCGAKFRAPGAED
FAFNSGGACPTCGGLGQVRQIDPALIIADENQTIEEGAVASWHLPGRNFMPIVAREIGIPIDIPYKDLSEADKTRVLHGP
KQTVAINIPSAKGKIFHMDNAVYENAFAAVEDSMATTKNERAINRLNRFYKFDTCPDCHGSRFNPQLFNYELNGQNIATV
SDMTVAALHDFATTIVPWLPTKMHHLGQSLVDELLLSLQPMEELGLDYLTLSRPGATLSTGELQRIQLGRTLRSATTGVL
YVLDEPSVGLHPANVAGLIKAFRGLVAQGNSVVVVDHDTSIISAADDVIEIGPGAGKHGGTVVGQGTVAAIKRDKKSLIA
PFLTGTATLRERPVLTDDALWKKGALAIEVAHHFNIQDITARIPKNRFTTVTGMSGAGKTTLVLDSLIPALIATAKKRPL
PTHVKAFDNGHIRHVVTVDSVPVGKNVRSTVATYTNILDHLRQLFAATPAAQANSWTASQFSYNVAAGACPTCGGTGQIS
LDVQYLPDITEVCPQCHGKRYNKQTLTVKWHGYSIADILDLAVDEALPIFKVQSAIANTLQILHDMGLGYLLLGESTPAL
SGGEAQRLKLTSRIGKRQTGTLFVFDEPSVGLHPLDIQQLVKVFDQLIQQGATVIAIEHDLDVIANADYVIDMGPAGGIN
GGNIVATGTPLAVSQNPTSVTGQYLKTHLALFHV

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=701, Percent_Identity=37.0898716119829, Blast_Score=433, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR013815
- InterPro:   IPR003593
- InterPro:   IPR004602 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 89583; Mature: 89451

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTTLPTHIQVRGAHVNNLKNIDIDIPLNEFVAITGRSGSGKSSLAMGVLYAEGARRYL
CCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHEEHHHHHHHHHHHH
NALSTFTRRRINQVGKASVDSVQYLPSALALRQRPQVPGVRSTVGTMSESLNILRLAFSR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSSAVCPNGHRMPPTLDVAENDGYVTCPTCGAKFRAPGAEDFAFNSGGACPTCGGLGQVR
HHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
QIDPALIIADENQTIEEGAVASWHLPGRNFMPIVAREIGIPIDIPYKDLSEADKTRVLHG
ECCCEEEEECCCCCHHCCCEEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHEEEC
PKQTVAINIPSAKGKIFHMDNAVYENAFAAVEDSMATTKNERAINRLNRFYKFDTCPDCH
CCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCCCCC
GSRFNPQLFNYELNGQNIATVSDMTVAALHDFATTIVPWLPTKMHHLGQSLVDELLLSLQ
CCCCCCEEEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PMEELGLDYLTLSRPGATLSTGELQRIQLGRTLRSATTGVLYVLDEPSVGLHPANVAGLI
CHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHH
KAFRGLVAQGNSVVVVDHDTSIISAADDVIEIGPGAGKHGGTVVGQGTVAAIKRDKKSLI
HHHHHHHHCCCEEEEEECCCCHHHCCCCCEEECCCCCCCCCEEEECCHHEEHHHHHHHHH
APFLTGTATLRERPVLTDDALWKKGALAIEVAHHFNIQDITARIPKNRFTTVTGMSGAGK
HHHHCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCC
TTLVLDSLIPALIATAKKRPLPTHVKAFDNGHIRHVVTVDSVPVGKNVRSTVATYTNILD
HHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
HLRQLFAATPAAQANSWTASQFSYNVAAGACPTCGGTGQISLDVQYLPDITEVCPQCHGK
HHHHHHHCCCCCCCCCCCHHHEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHHHCCC
RYNKQTLTVKWHGYSIADILDLAVDEALPIFKVQSAIANTLQILHDMGLGYLLLGESTPA
CCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
LSGGEAQRLKLTSRIGKRQTGTLFVFDEPSVGLHPLDIQQLVKVFDQLIQQGATVIAIEH
CCCCCHHHEEHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
DLDVIANADYVIDMGPAGGINGGNIVATGTPLAVSQNPTSVTGQYLKTHLALFHV
CCEEEECCCEEEECCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQTTLPTHIQVRGAHVNNLKNIDIDIPLNEFVAITGRSGSGKSSLAMGVLYAEGARRYL
CCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHEEHHHHHHHHHHHH
NALSTFTRRRINQVGKASVDSVQYLPSALALRQRPQVPGVRSTVGTMSESLNILRLAFSR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSSAVCPNGHRMPPTLDVAENDGYVTCPTCGAKFRAPGAEDFAFNSGGACPTCGGLGQVR
HHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
QIDPALIIADENQTIEEGAVASWHLPGRNFMPIVAREIGIPIDIPYKDLSEADKTRVLHG
ECCCEEEEECCCCCHHCCCEEEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHEEEC
PKQTVAINIPSAKGKIFHMDNAVYENAFAAVEDSMATTKNERAINRLNRFYKFDTCPDCH
CCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCCCCC
GSRFNPQLFNYELNGQNIATVSDMTVAALHDFATTIVPWLPTKMHHLGQSLVDELLLSLQ
CCCCCCEEEEEEECCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PMEELGLDYLTLSRPGATLSTGELQRIQLGRTLRSATTGVLYVLDEPSVGLHPANVAGLI
CHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHH
KAFRGLVAQGNSVVVVDHDTSIISAADDVIEIGPGAGKHGGTVVGQGTVAAIKRDKKSLI
HHHHHHHHCCCEEEEEECCCCHHHCCCCCEEECCCCCCCCCEEEECCHHEEHHHHHHHHH
APFLTGTATLRERPVLTDDALWKKGALAIEVAHHFNIQDITARIPKNRFTTVTGMSGAGK
HHHHCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCC
TTLVLDSLIPALIATAKKRPLPTHVKAFDNGHIRHVVTVDSVPVGKNVRSTVATYTNILD
HHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
HLRQLFAATPAAQANSWTASQFSYNVAAGACPTCGGTGQISLDVQYLPDITEVCPQCHGK
HHHHHHHCCCCCCCCCCCHHHEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHHHCCC
RYNKQTLTVKWHGYSIADILDLAVDEALPIFKVQSAIANTLQILHDMGLGYLLLGESTPA
CCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
LSGGEAQRLKLTSRIGKRQTGTLFVFDEPSVGLHPLDIQQLVKVFDQLIQQGATVIAIEH
CCCCCHHHEEHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
DLDVIANADYVIDMGPAGGINGGNIVATGTPLAVSQNPTSVTGQYLKTHLALFHV
CCEEEECCCEEEECCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]