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The map label for this gene is pucR [H]

Identifier: 28379205

GI number: 28379205

Start: 2408787

End: 2410376

Strand: Direct

Name: pucR [H]

Synonym: lp_2708

Alternate gene names: 28379205

Gene position: 2408787-2410376 (Clockwise)

Preceding gene: 28379193

Following gene: 28379206

Centisome position: 72.81

GC content: 44.09

Gene sequence:

>1590_bases
ATGCGTTTACAAACACTATTACAAACACCATCAATGCAACATATGCGGGTAATTGCGGGTGAACGCGGTCTCAAACGCGA
AATTAGTAATATCGGAATGATCGAGTCACCTGACATTGCTGACTACCTTGCTAATGGTCAGTTTTTGATTACGAACGGCT
ATCCCTTCGTCAATACAACCACCGACCCACTAACTTTGATCAAGGCGATGCACAATGCCAACTGTGCTGGTCTCGGATTT
AAGGATCATCGTTACGTTGACCATTTACCAAAAAAAGTGATTGAATTAGCGAACGAACTCGCTTTTCCAATCATTATTAC
GCCCGGTGATGAGTTGATTTCTGAAACCATGCGCAAAATGCTGAGCATCATCTTAAAGTCACAAACTAATGAGCTCAGTC
GCATCGTCAAGGCAAACCAAACACTAGCGGATTTGTTGCTCAAAGACCCAACCAACACCACGGTCTTGAATAAATGTAGC
GAGCTAATTCATCATCCTCTCTTCTTAATGGATAGTCATTTTCGGGTGGTCAGTGCTTCCCAAGATTTACCGATGACCCG
CAATACCTTGACTGATTTTTTACGCAATCAAACCGATATCGACTATTTCAACCTCAATACCCGCGTCATTCTCCCTTACC
AAGCAAATGACCTGACCATCATGCCACTATTTTCGGCTTATAAGGAAAATAAGGCCTTTGTAGGCGTCGTCGACTTGGAC
CCGGCCAACTCAACTGATCAGATGCTGACGCAAGTCGTCTTAAACACCTTGAGTTTCGTCAATGGTCGGGTGGACATGTT
AAACGAATCCGCATTCCGCAACCAAAGTGGTTTCTACTTAAACGTAATGGATGGCGGTATTTCAAACGACCTCGTGAATA
AGACTCTGAAAGCCCGCAATATTGATCCGAGTACGAAGTTCCACTGCGCCACCATTTTAGTCACGACTAATCACCAGGCC
CTCTTAAGTAACCATCTCTTGGAACAGGTTCAGCAACTGACACTGTGGTTTATTAAAGAATACCAAGCATCCGTCATTGT
TTTTTCATTAAAGCAGCAATTGGTCTTATTAATCAATGACCAGCAAAATGCCCAGCACTTTCTGACCGCCCTCGTTCAAT
TTATTCAGCCAAAGTTGGACAGACAGGCGCGTTTGATTGCTGGTTACAGTTATTCGACTCTACCACTAACCGAACTCGCA
ACAACCTATAATGAAGCGGCAGAAGCCTTGGCACTCAGCAAAAACAGTCCCCACGCAGTCACGATCTATCGGCCCAAGTA
CGTCAAGGAACTAATTTCACTGATTCCACAAAATGAAGCGCGATCGTTTGTCGAACGGGTTTTAGGTGGACTCGTCAGTG
GTGTCAGTGCGAATGAACAACTTAATCTACTCACGACCCTGTATGGCTATTTTTATTACCATCAAAACATTGCCGAAGTG
GCCGGCCACCTAGATATTCACCGCAATACGGTGATTTACCGCCTTAAAAAGATCGAAAAAATGCTAACGTTGAACTTGGA
CGATCCTGAACAGACCCAAACACTAGAAATGGCAGTGCTACTTTGGCATAATCAACAATCACAAAAGTGA

Upstream 100 bases:

>100_bases
CTTCATTTGTTTTTAATCTATTTTTCATTTAATTATAGTCAAACTGCCAAATTATCGGTATACTACTTGTTAAAGATAAC
TAATTTTAGGGGGACTTACC

Downstream 100 bases:

>100_bases
ACGTTTTCATTTTCATCTTCCAAAAAAATATCGTTTTCACGAACATTAATTTATTCGGCTACATTTGTATTCGGTTTTCA
TCTGTGCTAGAATAAGTCTC

Product: purine transport regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MRLQTLLQTPSMQHMRVIAGERGLKREISNIGMIESPDIADYLANGQFLITNGYPFVNTTTDPLTLIKAMHNANCAGLGF
KDHRYVDHLPKKVIELANELAFPIIITPGDELISETMRKMLSIILKSQTNELSRIVKANQTLADLLLKDPTNTTVLNKCS
ELIHHPLFLMDSHFRVVSASQDLPMTRNTLTDFLRNQTDIDYFNLNTRVILPYQANDLTIMPLFSAYKENKAFVGVVDLD
PANSTDQMLTQVVLNTLSFVNGRVDMLNESAFRNQSGFYLNVMDGGISNDLVNKTLKARNIDPSTKFHCATILVTTNHQA
LLSNHLLEQVQQLTLWFIKEYQASVIVFSLKQQLVLLINDQQNAQHFLTALVQFIQPKLDRQARLIAGYSYSTLPLTELA
TTYNEAAEALALSKNSPHAVTIYRPKYVKELISLIPQNEARSFVERVLGGLVSGVSANEQLNLLTTLYGYFYYHQNIAEV
AGHLDIHRNTVIYRLKKIEKMLTLNLDDPEQTQTLEMAVLLWHNQQSQK

Sequences:

>Translated_529_residues
MRLQTLLQTPSMQHMRVIAGERGLKREISNIGMIESPDIADYLANGQFLITNGYPFVNTTTDPLTLIKAMHNANCAGLGF
KDHRYVDHLPKKVIELANELAFPIIITPGDELISETMRKMLSIILKSQTNELSRIVKANQTLADLLLKDPTNTTVLNKCS
ELIHHPLFLMDSHFRVVSASQDLPMTRNTLTDFLRNQTDIDYFNLNTRVILPYQANDLTIMPLFSAYKENKAFVGVVDLD
PANSTDQMLTQVVLNTLSFVNGRVDMLNESAFRNQSGFYLNVMDGGISNDLVNKTLKARNIDPSTKFHCATILVTTNHQA
LLSNHLLEQVQQLTLWFIKEYQASVIVFSLKQQLVLLINDQQNAQHFLTALVQFIQPKLDRQARLIAGYSYSTLPLTELA
TTYNEAAEALALSKNSPHAVTIYRPKYVKELISLIPQNEARSFVERVLGGLVSGVSANEQLNLLTTLYGYFYYHQNIAEV
AGHLDIHRNTVIYRLKKIEKMLTLNLDDPEQTQTLEMAVLLWHNQQSQK
>Mature_529_residues
MRLQTLLQTPSMQHMRVIAGERGLKREISNIGMIESPDIADYLANGQFLITNGYPFVNTTTDPLTLIKAMHNANCAGLGF
KDHRYVDHLPKKVIELANELAFPIIITPGDELISETMRKMLSIILKSQTNELSRIVKANQTLADLLLKDPTNTTVLNKCS
ELIHHPLFLMDSHFRVVSASQDLPMTRNTLTDFLRNQTDIDYFNLNTRVILPYQANDLTIMPLFSAYKENKAFVGVVDLD
PANSTDQMLTQVVLNTLSFVNGRVDMLNESAFRNQSGFYLNVMDGGISNDLVNKTLKARNIDPSTKFHCATILVTTNHQA
LLSNHLLEQVQQLTLWFIKEYQASVIVFSLKQQLVLLINDQQNAQHFLTALVQFIQPKLDRQARLIAGYSYSTLPLTELA
TTYNEAAEALALSKNSPHAVTIYRPKYVKELISLIPQNEARSFVERVLGGLVSGVSANEQLNLLTTLYGYFYYHQNIAEV
AGHLDIHRNTVIYRLKKIEKMLTLNLDDPEQTQTLEMAVLLWHNQQSQK

Specific function: Activates the expression of pucFG, pucH, pucI, pucJKLM and guaD, while it represses pucABCDE and its own expression [H]

COG id: COG2508

COG function: function code TQ; Regulator of polyketide synthase expression

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012914 [H]

Pfam domain/function: PF07905 PucR [H]

EC number: NA

Molecular weight: Translated: 59875; Mature: 59875

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLQTLLQTPSMQHMRVIAGERGLKREISNIGMIESPDIADYLANGQFLITNGYPFVNTT
CCCHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHCCCCEEEECCCCCCCCC
TDPLTLIKAMHNANCAGLGFKDHRYVDHLPKKVIELANELAFPIIITPGDELISETMRKM
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
LSIILKSQTNELSRIVKANQTLADLLLKDPTNTTVLNKCSELIHHPLFLMDSHFRVVSAS
HHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHEECCCEEEEECC
QDLPMTRNTLTDFLRNQTDIDYFNLNTRVILPYQANDLTIMPLFSAYKENKAFVGVVDLD
CCCCCHHHHHHHHHCCCCCCEEEECCEEEEEEEECCCEEEEEHHHHHCCCCCEEEEEECC
PANSTDQMLTQVVLNTLSFVNGRVDMLNESAFRNQSGFYLNVMDGGISNDLVNKTLKARN
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCC
IDPSTKFHCATILVTTNHQALLSNHLLEQVQQLTLWFIKEYQASVIVFSLKQQLVLLIND
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECC
QQNAQHFLTALVQFIQPKLDRQARLIAGYSYSTLPLTELATTYNEAAEALALSKNSPHAV
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
TIYRPKYVKELISLIPQNEARSFVERVLGGLVSGVSANEQLNLLTTLYGYFYYHQNIAEV
EEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AGHLDIHRNTVIYRLKKIEKMLTLNLDDPEQTQTLEMAVLLWHNQQSQK
HHCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MRLQTLLQTPSMQHMRVIAGERGLKREISNIGMIESPDIADYLANGQFLITNGYPFVNTT
CCCHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHCCCCEEEECCCCCCCCC
TDPLTLIKAMHNANCAGLGFKDHRYVDHLPKKVIELANELAFPIIITPGDELISETMRKM
CCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHH
LSIILKSQTNELSRIVKANQTLADLLLKDPTNTTVLNKCSELIHHPLFLMDSHFRVVSAS
HHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHEECCCEEEEECC
QDLPMTRNTLTDFLRNQTDIDYFNLNTRVILPYQANDLTIMPLFSAYKENKAFVGVVDLD
CCCCCHHHHHHHHHCCCCCCEEEECCEEEEEEEECCCEEEEEHHHHHCCCCCEEEEEECC
PANSTDQMLTQVVLNTLSFVNGRVDMLNESAFRNQSGFYLNVMDGGISNDLVNKTLKARN
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCC
IDPSTKFHCATILVTTNHQALLSNHLLEQVQQLTLWFIKEYQASVIVFSLKQQLVLLIND
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECC
QQNAQHFLTALVQFIQPKLDRQARLIAGYSYSTLPLTELATTYNEAAEALALSKNSPHAV
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
TIYRPKYVKELISLIPQNEARSFVERVLGGLVSGVSANEQLNLLTTLYGYFYYHQNIAEV
EEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AGHLDIHRNTVIYRLKKIEKMLTLNLDDPEQTQTLEMAVLLWHNQQSQK
HHCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136; 12029039 [H]