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The map label for this gene is araT2 [H]

Identifier: 28379188

GI number: 28379188

Start: 2383592

End: 2384764

Strand: Direct

Name: araT2 [H]

Synonym: lp_2684

Alternate gene names: 28379188

Gene position: 2383592-2384764 (Clockwise)

Preceding gene: 28379186

Following gene: 28379189

Centisome position: 72.05

GC content: 48.42

Gene sequence:

>1173_bases
ATGATGAATACAAATATTCGGATCCAACAAATTCAAGTCTCTGGCATCCGACGCTTCGATGAAGCAATCAGTCAAATTCC
CGATATTATCAGATTAACGGTCGGCGAACCTGACTTACCCACCCCAAGTCACGTAAAAAAAGCGGCAATTCAATCTATTC
ATAATGATTGGACACACTACTCGCCACTAATGGGCTTTGCCGCTTTGCAAGATGCTGCGAGTCACTACTTTCAACAGAAA
TACCAACTCACCTATGCACCTGAGCAAATCATTGCAACAGTCGGCGCTAGTGAAGCCGTGGCAACGACCCTGCTCACTTT
ACTTAATCCTGGCGATACCGTCTTATTGCCAACACCGGCCTACACGAACTATCAACCCGTCGTTGACATCGCAAACGCAC
AATTAGCTCCCATTGACACAACCGCAACGGGTTATAAATTAACACCCAGTGCGTTACAAGCTGCGCTAGATGATCACCGT
CACGACCACGTCAAGGCCTTAATTCTAAACTACCCAACCAACCCCACCGGCGTCACGTACACTGATGATGAATTATGGGC
TTTGCAAGCCGTCATTGCTACCGCTGGAATCTACGTTATTAGCGATGAGATTTACAGTGAACTAACCTATGAACAGCCCC
ATACTGCTTTTGCCACACTATATCCAAGCAAAACGATCACAATCAATGGCCTCTCCAAATCGCATGCCATGACTGGTTGG
CGACTGGGATTCATCATGGCCCCAAGTAACTTGATTACCGAGATGAAGAAGACCCACCAGTACCTCGTTACTTCAACGAG
TTCAATCACCCAAGCGGCTGGTATCGAAGCACTTACCCATGGTCTGGATGATGGCTCAGAAATGCGTGGCGTCTATCAAA
CACGCCGCGATTACGTCGTCAAACGTCTGAGTGAAATTGGATTCAATTATATTTATCCGACGGGCGCATTCTATATCTTT
GTCCAGCTACCACAGGATTTCCAAGGCACCAGCTGGGACTTTGCGACCCGACTCGCACACGAGGCCCAAGTTGCTGTCGT
TCCTGGCTCAGCATTTGGTACGAGTGGCGAGGGTTGGTTCCGGATAAGTTATGCAGCCAGTCAATCGGCACTACGCGAAG
GGCTAAATCGTTTAGCCTTATGGCGCGCCCAAACTACCACACAGGAGGATTAG

Upstream 100 bases:

>100_bases
CATCACACAACTGTCCTTTCATTTTTATCAAAATTGTCTATTTCTAACCGGACGATTGTTGTTTATTATAAACGGTAATC
ACGTTGAGAGGAAGGTCCTA

Downstream 100 bases:

>100_bases
CCACATGAATTTAGCATCCGCACACCTGATTACCGCCATGGTCACCCCATTTGATGACCAACAACACATTGATTTCCACC
GCTTAGAGCAACTGATCGAA

Product: aromatic amino acid specific aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MMNTNIRIQQIQVSGIRRFDEAISQIPDIIRLTVGEPDLPTPSHVKKAAIQSIHNDWTHYSPLMGFAALQDAASHYFQQK
YQLTYAPEQIIATVGASEAVATTLLTLLNPGDTVLLPTPAYTNYQPVVDIANAQLAPIDTTATGYKLTPSALQAALDDHR
HDHVKALILNYPTNPTGVTYTDDELWALQAVIATAGIYVISDEIYSELTYEQPHTAFATLYPSKTITINGLSKSHAMTGW
RLGFIMAPSNLITEMKKTHQYLVTSTSSITQAAGIEALTHGLDDGSEMRGVYQTRRDYVVKRLSEIGFNYIYPTGAFYIF
VQLPQDFQGTSWDFATRLAHEAQVAVVPGSAFGTSGEGWFRISYAASQSALREGLNRLALWRAQTTTQED

Sequences:

>Translated_390_residues
MMNTNIRIQQIQVSGIRRFDEAISQIPDIIRLTVGEPDLPTPSHVKKAAIQSIHNDWTHYSPLMGFAALQDAASHYFQQK
YQLTYAPEQIIATVGASEAVATTLLTLLNPGDTVLLPTPAYTNYQPVVDIANAQLAPIDTTATGYKLTPSALQAALDDHR
HDHVKALILNYPTNPTGVTYTDDELWALQAVIATAGIYVISDEIYSELTYEQPHTAFATLYPSKTITINGLSKSHAMTGW
RLGFIMAPSNLITEMKKTHQYLVTSTSSITQAAGIEALTHGLDDGSEMRGVYQTRRDYVVKRLSEIGFNYIYPTGAFYIF
VQLPQDFQGTSWDFATRLAHEAQVAVVPGSAFGTSGEGWFRISYAASQSALREGLNRLALWRAQTTTQED
>Mature_390_residues
MMNTNIRIQQIQVSGIRRFDEAISQIPDIIRLTVGEPDLPTPSHVKKAAIQSIHNDWTHYSPLMGFAALQDAASHYFQQK
YQLTYAPEQIIATVGASEAVATTLLTLLNPGDTVLLPTPAYTNYQPVVDIANAQLAPIDTTATGYKLTPSALQAALDDHR
HDHVKALILNYPTNPTGVTYTDDELWALQAVIATAGIYVISDEIYSELTYEQPHTAFATLYPSKTITINGLSKSHAMTGW
RLGFIMAPSNLITEMKKTHQYLVTSTSSITQAAGIEALTHGLDDGSEMRGVYQTRRDYVVKRLSEIGFNYIYPTGAFYIF
VQLPQDFQGTSWDFATRLAHEAQVAVVPGSAFGTSGEGWFRISYAASQSALREGLNRLALWRAQTTTQED

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=406, Percent_Identity=26.1083743842365, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI56713254, Length=406, Percent_Identity=26.1083743842365, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=21.608040201005, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=21.608040201005, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=23.5751295336788, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881281, Length=309, Percent_Identity=20.7119741100324, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187936925, Length=363, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI14211921, Length=363, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI149944424, Length=317, Percent_Identity=22.7129337539432, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=29.0760869565217, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1786816, Length=369, Percent_Identity=25.7452574525745, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788627, Length=369, Percent_Identity=23.5772357723577, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787909, Length=363, Percent_Identity=22.5895316804408, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787710, Length=291, Percent_Identity=25.085910652921, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=26.530612244898, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=391, Percent_Identity=25.8312020460358, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=26.530612244898, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=25.25, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=356, Percent_Identity=24.7191011235955, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=353, Percent_Identity=23.2294617563739, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573069, Length=394, Percent_Identity=23.8578680203046, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646114, Length=394, Percent_Identity=23.8578680203046, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573067, Length=394, Percent_Identity=23.8578680203046, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573065, Length=394, Percent_Identity=23.8578680203046, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=23.5443037974684, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 43039; Mature: 43039

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTNIRIQQIQVSGIRRFDEAISQIPDIIRLTVGEPDLPTPSHVKKAAIQSIHNDWTHY
CCCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHH
SPLMGFAALQDAASHYFQQKYQLTYAPEQIIATVGASEAVATTLLTLLNPGDTVLLPTPA
HHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCC
YTNYQPVVDIANAQLAPIDTTATGYKLTPSALQAALDDHRHDHVKALILNYPTNPTGVTY
CCCCCCCEEECCCEECCCCCCCCCCEECHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEE
TDDELWALQAVIATAGIYVISDEIYSELTYEQPHTAFATLYPSKTITINGLSKSHAMTGW
CCCHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCCCE
RLGFIMAPSNLITEMKKTHQYLVTSTSSITQAAGIEALTHGLDDGSEMRGVYQTRRDYVV
EEEEEECCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KRLSEIGFNYIYPTGAFYIFVQLPQDFQGTSWDFATRLAHEAQVAVVPGSAFGTSGEGWF
HHHHHCCCEEEECCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEE
RISYAASQSALREGLNRLALWRAQTTTQED
EEEEHHHHHHHHHHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MMNTNIRIQQIQVSGIRRFDEAISQIPDIIRLTVGEPDLPTPSHVKKAAIQSIHNDWTHY
CCCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHH
SPLMGFAALQDAASHYFQQKYQLTYAPEQIIATVGASEAVATTLLTLLNPGDTVLLPTPA
HHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCC
YTNYQPVVDIANAQLAPIDTTATGYKLTPSALQAALDDHRHDHVKALILNYPTNPTGVTY
CCCCCCCEEECCCEECCCCCCCCCCEECHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEE
TDDELWALQAVIATAGIYVISDEIYSELTYEQPHTAFATLYPSKTITINGLSKSHAMTGW
CCCHHHHHHHHHHHCCEEEEEHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCCCE
RLGFIMAPSNLITEMKKTHQYLVTSTSSITQAAGIEALTHGLDDGSEMRGVYQTRRDYVV
EEEEEECCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KRLSEIGFNYIYPTGAFYIFVQLPQDFQGTSWDFATRLAHEAQVAVVPGSAFGTSGEGWF
HHHHHCCCEEEECCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEE
RISYAASQSALREGLNRLALWRAQTTTQED
EEEEHHHHHHHHHHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]