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The map label for this gene is adrA [H]

Identifier: 28379068

GI number: 28379068

Start: 2251207

End: 2252397

Strand: Direct

Name: adrA [H]

Synonym: lp_2524

Alternate gene names: 28379068

Gene position: 2251207-2252397 (Clockwise)

Preceding gene: 28379065

Following gene: 28379071

Centisome position: 68.05

GC content: 44.58

Gene sequence:

>1191_bases
GTGTTACATCTACTTACGCTATCGAGCTTAGGCCGAGATCTTTTTAATATCAAAATGCTAATTGTCATTCTCATTACAAT
TGGCCTGATCACCCTAATGACCATTCTGACCTACCTCCTAGAGCAACAGGTCCATCGTCGTCAAAATCGATATTGGACTA
TTGGGGCCCATGGTGCCGAGGCTTTAAGTGTCCTCATTAGTATGATCCTATTACGACAAATATTCATTACGCTGAATTCA
GGTAGCATTATCAGTTGGACCTACGCAACGGTTCAATTAACGATTCTTCTGTTCAGCCTTAACACCATGCGCAACCTGGC
CGTTGAAATTATTAACCTGTTAATGCCATTGTTCATTTATGGTCAGGCCATCTGGTTGGGCCACAGCACGCAGTACCTGC
CAGTTTTTCTGGCCATGGCCATTATCTTGATTAGTACAGTCGTCTATATTACTCATAACTATCAAGAATTACACGCTACT
CAATGGAAGTATCTCCTGTTCCAAATACTATATAGTGGCACTTGGTGGGGCGTTATTTGGTCAGTTCATCCGTTCAAATT
GAGCCATACACTCGTCATCATTCTAGCCTTTGTCCTTTACATGTGGTTGATTCGTTTAGCAGTCAATCGCGTCCAAAAGT
TTTTCAATGAAGTGCTCACCTTTGATCAACAAGTCAATTACGATGAATTAACCGGTATTCGTAACCGCGCCAGCTTTGAC
ACGCATGCGCGTGAAGTGTTTGCCGCGTATCAGCACCATCAAATGGGGCCCGTCACTATGGTCATGTTCGATATTGACCA
CTTTAAAGCCTTTAACGATCAGTACGGCCATCTGGCTGGCGACGCCGTACTCCGACACGTGGCGCATTTTGTTGAACTTG
AACTTAATCAGCGCAGCACTCACGGTCAGATCTTCCGCTATGGCGGTGAAGAATTCGTCATCATTTTTCGTGGCATCTCA
GCGCTTGAAGCTGGTCAAATAATGCGTACGATTCAGCGTAAACTGAAAACAGTACCAATCAAATTTAACGTTCAAACGTT
GAACGTGACCGTTTCAATTGGCATTTCAGAATTGCAACCAACCGACCAGACTTTCACTGATTGGTTCGTCCGCGTTGACG
ACTACCTCTATCAGTCCAAGCAGGCCGGTCGCGACCAGACCACGGTTGAAAGTCAATTACTAACGGATTAA

Upstream 100 bases:

>100_bases
TGATTTTTAAATTATTGCAAACCGCTGTTAACAGTTACCTGCGTAACGTGTTATGATTAAAGGACAAATTAATTAAACGC
AACAATTATGGGGGCGCACT

Downstream 100 bases:

>100_bases
TAATTGTTCCCAAAAGGCCGTTAATTTGTAAATTCGTTCCCGATTTACAAATTAACGGCCTTTTTGGGTTTAGCGATTAC
CGATGGGGACAATGGCGCGC

Product: diguanylate cyclase/phosphodiesterase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MLHLLTLSSLGRDLFNIKMLIVILITIGLITLMTILTYLLEQQVHRRQNRYWTIGAHGAEALSVLISMILLRQIFITLNS
GSIISWTYATVQLTILLFSLNTMRNLAVEIINLLMPLFIYGQAIWLGHSTQYLPVFLAMAIILISTVVYITHNYQELHAT
QWKYLLFQILYSGTWWGVIWSVHPFKLSHTLVIILAFVLYMWLIRLAVNRVQKFFNEVLTFDQQVNYDELTGIRNRASFD
THAREVFAAYQHHQMGPVTMVMFDIDHFKAFNDQYGHLAGDAVLRHVAHFVELELNQRSTHGQIFRYGGEEFVIIFRGIS
ALEAGQIMRTIQRKLKTVPIKFNVQTLNVTVSIGISELQPTDQTFTDWFVRVDDYLYQSKQAGRDQTTVESQLLTD

Sequences:

>Translated_396_residues
MLHLLTLSSLGRDLFNIKMLIVILITIGLITLMTILTYLLEQQVHRRQNRYWTIGAHGAEALSVLISMILLRQIFITLNS
GSIISWTYATVQLTILLFSLNTMRNLAVEIINLLMPLFIYGQAIWLGHSTQYLPVFLAMAIILISTVVYITHNYQELHAT
QWKYLLFQILYSGTWWGVIWSVHPFKLSHTLVIILAFVLYMWLIRLAVNRVQKFFNEVLTFDQQVNYDELTGIRNRASFD
THAREVFAAYQHHQMGPVTMVMFDIDHFKAFNDQYGHLAGDAVLRHVAHFVELELNQRSTHGQIFRYGGEEFVIIFRGIS
ALEAGQIMRTIQRKLKTVPIKFNVQTLNVTVSIGISELQPTDQTFTDWFVRVDDYLYQSKQAGRDQTTVESQLLTD
>Mature_396_residues
MLHLLTLSSLGRDLFNIKMLIVILITIGLITLMTILTYLLEQQVHRRQNRYWTIGAHGAEALSVLISMILLRQIFITLNS
GSIISWTYATVQLTILLFSLNTMRNLAVEIINLLMPLFIYGQAIWLGHSTQYLPVFLAMAIILISTVVYITHNYQELHAT
QWKYLLFQILYSGTWWGVIWSVHPFKLSHTLVIILAFVLYMWLIRLAVNRVQKFFNEVLTFDQQVNYDELTGIRNRASFD
THAREVFAAYQHHQMGPVTMVMFDIDHFKAFNDQYGHLAGDAVLRHVAHFVELELNQRSTHGQIFRYGGEEFVIIFRGIS
ALEAGQIMRTIQRKLKTVPIKFNVQTLNVTVSIGISELQPTDQTFTDWFVRVDDYLYQSKQAGRDQTTVESQLLTD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=36.3636363636364, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=32.9268292682927, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=30.635838150289, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787056, Length=163, Percent_Identity=31.2883435582822, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=33.5365853658537, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=32.3863636363636, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788381, Length=169, Percent_Identity=30.1775147928994, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787262, Length=173, Percent_Identity=27.7456647398844, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787541, Length=169, Percent_Identity=31.9526627218935, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI145693134, Length=196, Percent_Identity=29.0816326530612, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 45819; Mature: 45819

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLLTLSSLGRDLFNIKMLIVILITIGLITLMTILTYLLEQQVHRRQNRYWTIGAHGAE
CEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
ALSVLISMILLRQIFITLNSGSIISWTYATVQLTILLFSLNTMRNLAVEIINLLMPLFIY
HHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQAIWLGHSTQYLPVFLAMAIILISTVVYITHNYQELHATQWKYLLFQILYSGTWWGVIW
CCHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEHEE
SVHPFKLSHTLVIILAFVLYMWLIRLAVNRVQKFFNEVLTFDQQVNYDELTGIRNRASFD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCH
THAREVFAAYQHHQMGPVTMVMFDIDHFKAFNDQYGHLAGDAVLRHVAHFVELELNQRST
HHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
HGQIFRYGGEEFVIIFRGISALEAGQIMRTIQRKLKTVPIKFNVQTLNVTVSIGISELQP
CCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECHHHCCC
TDQTFTDWFVRVDDYLYQSKQAGRDQTTVESQLLTD
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLHLLTLSSLGRDLFNIKMLIVILITIGLITLMTILTYLLEQQVHRRQNRYWTIGAHGAE
CEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
ALSVLISMILLRQIFITLNSGSIISWTYATVQLTILLFSLNTMRNLAVEIINLLMPLFIY
HHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQAIWLGHSTQYLPVFLAMAIILISTVVYITHNYQELHATQWKYLLFQILYSGTWWGVIW
CCHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEHEE
SVHPFKLSHTLVIILAFVLYMWLIRLAVNRVQKFFNEVLTFDQQVNYDELTGIRNRASFD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCH
THAREVFAAYQHHQMGPVTMVMFDIDHFKAFNDQYGHLAGDAVLRHVAHFVELELNQRST
HHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
HGQIFRYGGEEFVIIFRGISALEAGQIMRTIQRKLKTVPIKFNVQTLNVTVSIGISELQP
CCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECHHHCCC
TDQTFTDWFVRVDDYLYQSKQAGRDQTTVESQLLTD
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]