Click here to switch to the map view.

The map label for this gene is accD2

Identifier: 28378369

GI number: 28378369

Start: 1529686

End: 1530531

Strand: Direct

Name: accD2

Synonym: lp_1679

Alternate gene names: 28378369

Gene position: 1529686-1530531 (Clockwise)

Preceding gene: 28378368

Following gene: 28378370

Centisome position: 46.24

GC content: 48.23

Gene sequence:

>846_bases
GTGATGCCCAAGCGCAAGTTTCAAGCACCCACTGAACGGCAGTTAGCTGTTCGACGGGATAATATCCCAGACGCGTTATT
GACGCGCTGTCCAGTTTGTCATGAAGATTGTTATACCCAAGATCTCGGTGAATTCAAGGTATGTCCCCATTGTGATTATG
GGTTTCGCTTGCCTGCTTGGCAACGTGTTCAACAATTGACGGCGAGTTTTGAAGAGCGGGATGCGGACCTAAGTGCGCCC
GTCAGTTTTGATGACCCTGCATATTTAGAAAAGTTGCAGCGTGCCAAAGCAGCCTCACACTTGAATGAGAGCGTATTGAC
TGGTATTGGGACGTTAGCGACTTATCAATTTGGGTTAGGTGTCATGGAAACTAAATTTATGATGGGGAGTTTGGGGGCGG
CAACCGGTGAGAAAATTACGCGATTATTTGAAACTTGTACGACCCAAAAACTTCCCGTTGTGATGGTTACTGCTTCTGGC
GGGGCGCGTATGCAAGAAGGCGCTCGTGCATTGATGCAAATGGCTAAGGTGTCCACGGCGGTTGCAAATCACCGAAAAGC
TGGACTATTGTATATTACAATTTTAACTGATCCAACCACTGGTGGTGTCACGGCTAGTTTTGCGATGCAGGGTGACATTA
TGTTGAGCGAGCCACGAGCGCTCATTGGATTCGCGGGTCGGCGAGTCATTGAACAAACCATTCAACAGACACCACCTGCG
GATTTCCAACGGGCGGAAACCTTATTGGCCAATGGATGGTTAGATCAAATTGTGCCCCGACCAGCCTTACGGAAAACACT
ACAACGATTATTAACAATCACTCAGGGAGGTCATCAGGATGTCTAA

Upstream 100 bases:

>100_bases
AACCGGACCTTCTTAGCAGGATTAGTTGCAGATTCGACTGTTAGCCGTGGTACCTATACCACAGCTTATATCGAACAAGA
CTTTTTGAAAGGATGGTTAA

Downstream 100 bases:

>100_bases
AGTAACGGCCTACGAACAAGTTCAAGCAGCCCGGGATGCTAGTAAGATTAGCATTCAAACGTTGATTGATGGCTTGACAG
AGGATTTTTTTGATTGTCAT

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta 2; Acetyl-CoA carboxylase carboxyltransferase subunit beta 2

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MMPKRKFQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAWQRVQQLTASFEERDADLSAP
VSFDDPAYLEKLQRAKAASHLNESVLTGIGTLATYQFGLGVMETKFMMGSLGAATGEKITRLFETCTTQKLPVVMVTASG
GARMQEGARALMQMAKVSTAVANHRKAGLLYITILTDPTTGGVTASFAMQGDIMLSEPRALIGFAGRRVIEQTIQQTPPA
DFQRAETLLANGWLDQIVPRPALRKTLQRLLTITQGGHQDV

Sequences:

>Translated_281_residues
MMPKRKFQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAWQRVQQLTASFEERDADLSAP
VSFDDPAYLEKLQRAKAASHLNESVLTGIGTLATYQFGLGVMETKFMMGSLGAATGEKITRLFETCTTQKLPVVMVTASG
GARMQEGARALMQMAKVSTAVANHRKAGLLYITILTDPTTGGVTASFAMQGDIMLSEPRALIGFAGRRVIEQTIQQTPPA
DFQRAETLLANGWLDQIVPRPALRKTLQRLLTITQGGHQDV
>Mature_281_residues
MMPKRKFQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAWQRVQQLTASFEERDADLSAP
VSFDDPAYLEKLQRAKAASHLNESVLTGIGTLATYQFGLGVMETKFMMGSLGAATGEKITRLFETCTTQKLPVVMVTASG
GARMQEGARALMQMAKVSTAVANHRKAGLLYITILTDPTTGGVTASFAMQGDIMLSEPRALIGFAGRRVIEQTIQQTPPA
DFQRAETLLANGWLDQIVPRPALRKTLQRLLTITQGGHQDV

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=260, Percent_Identity=40.3846153846154, Blast_Score=188, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD2_LACPJ (C6VQ34)

Other databases:

- EMBL:   CP001617
- RefSeq:   YP_003062996.1
- ProteinModelPortal:   C6VQ34
- SMR:   C6VQ34
- GeneID:   8188244
- GenomeReviews:   CP001617_GR
- KEGG:   lpj:JDM1_1412
- OMA:   CGYGFRL
- ProtClustDB:   CLSK2520254
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 30944; Mature: 30944

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPKRKFQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAW
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHH
QRVQQLTASFEERDADLSAPVSFDDPAYLEKLQRAKAASHLNESVLTGIGTLATYQFGLG
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VMETKFMMGSLGAATGEKITRLFETCTTQKLPVVMVTASGGARMQEGARALMQMAKVSTA
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
VANHRKAGLLYITILTDPTTGGVTASFAMQGDIMLSEPRALIGFAGRRVIEQTIQQTPPA
HHHCCCCCEEEEEEEECCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHCCCH
DFQRAETLLANGWLDQIVPRPALRKTLQRLLTITQGGHQDV
HHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMPKRKFQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAW
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHH
QRVQQLTASFEERDADLSAPVSFDDPAYLEKLQRAKAASHLNESVLTGIGTLATYQFGLG
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VMETKFMMGSLGAATGEKITRLFETCTTQKLPVVMVTASGGARMQEGARALMQMAKVSTA
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
VANHRKAGLLYITILTDPTTGGVTASFAMQGDIMLSEPRALIGFAGRRVIEQTIQQTPPA
HHHCCCCCEEEEEEEECCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHCCCH
DFQRAETLLANGWLDQIVPRPALRKTLQRLLTITQGGHQDV
HHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA