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The map label for this gene is sufB [H]

Identifier: 28378189

GI number: 28378189

Start: 1348912

End: 1350318

Strand: Direct

Name: sufB [H]

Synonym: lp_1472

Alternate gene names: 28378189

Gene position: 1348912-1350318 (Clockwise)

Preceding gene: 28378188

Following gene: 28378190

Centisome position: 40.77

GC content: 45.98

Gene sequence:

>1407_bases
ATGAGTGAAGTACCTGACGTGGTCAAAAATGACCGTGATTATGAATATGGATTTCATGACGATGTCAAACCAGCATATTC
AACTGGGCGAGGATTAACGGAAGCCACGGTGCGCGAAATTTCCGCGGCAAAACATGAGCCACAATGGATGTTGGATTATC
GGTTAAATGCCTATCATGAGTATTTAAAGATGCCGATGCCTAAGTTTGGCCCGGATCTCACGAAACTCGACTTGAAGGAC
ATGCTGTATTATCAGAAGATGACCGATAAAAAGTTCCGTGACTGGAAAGAAGTCCCAGCTGACTTGAAGCGGACGTTCGA
CCGGTTAGGTGTGCCTGAAGCTGAACGGAAATACTTAGCCGGTTCATCGGCGCAGTATGAATCTGAAGTCGTTTATCACA
ATATGCGTAAAGATTTTGAAAAGTTAGGTATTATTTTTACCGATACCGATACGGCGCTTCACGATTATCCAGAACTGTTC
AAGAAGTGGTTTGGGAAACTCGTCAAACCAACCGATAACAAGTTTGCGGCTTTAAACGCGGCGGTCTGGTCAGGTGGGTC
CTTCATTTACGTGCCTAAGGGTGTCCAGACGAAGACGCCAATTCAGTCATATTTCCGGTTAAATGCTGAAAACTCGGGTC
AGTTTGAGCGGACTTTGATTATCGTGGAAGATGGTGCCAGTGTCGACTATGTCGAAGGGTGTACGGCCCCTAATTATTCT
TCAGATAGTTTGCACGCGGCCGTTGTTGAAGTCAATGTTGAGCCCAACGCTTACTGCCGTTATACAACGATTCAAAACTG
GTCTGACAATGTTTATAGCCTGGAAACTAAGCGAGCTGCAGCGGCCGAAAATGCCACGATGGAATGGGTCGATGGGAATT
TAGGTTCGAAGGTTACGATGAAGTACCCAAGCGTTTATTTGAATGGGGAAGGTGCCCGCGGGACCATGTTATCGATCGCG
GTTGCCAGCAATGGCATCCACCAAGATTCTGGTGCTCGGATGATTCATAATGCTAAGAATACCTCCAGTTCGATTGTTTC
GAAGTCCATCGCTAAGACTGGTGGTGCGACTGATTACCGTGGAACCGTGCGTTTTGCCAAGCATTCAGACGGTTCCAAAG
CGCATGTTGAGTGTGATACGATCATTATGGATGACCAGTCGTCTTCCAACACGATTCCGTATAATGAAATCGACAGTGCT
AACGTCGCGATGGAACACGAAGCTAAGGTGTCCAAAATCTCAGAAGAACAGCTCTACTACTTGATGAGCCGAGGAATTTC
AGAAGCTAAGGCAACCGAAATGATTATCATGGGATTCGTAGAACCATTTACGAAGCAATTACCGATGGAATATGCTGTTG
AATTAAACCGGTTAATCAGCTTTGAGATGGAAGGTTCAATCGGGTAG

Upstream 100 bases:

>100_bases
TTATGCAATTTCCGGCACGAATCAAATGTGCCACGCTAGCTTGGTGGGCTTTGCAACGGGCATTGCTTGCTGAAAATGGC
AATGAGGAGGAATCAGAAGT

Downstream 100 bases:

>100_bases
TAAGGGGTCAAGTGAGATGAAAAAGACACGACGCATCTTATTAGGATTAGCGCTCATCATCGGGTTAAGCGTTGGGGCCG
GTTGCCGTTCGACTGCTAGT

Product: ABC transporter component, iron regulated (putative)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSEVPDVVKNDRDYEYGFHDDVKPAYSTGRGLTEATVREISAAKHEPQWMLDYRLNAYHEYLKMPMPKFGPDLTKLDLKD
MLYYQKMTDKKFRDWKEVPADLKRTFDRLGVPEAERKYLAGSSAQYESEVVYHNMRKDFEKLGIIFTDTDTALHDYPELF
KKWFGKLVKPTDNKFAALNAAVWSGGSFIYVPKGVQTKTPIQSYFRLNAENSGQFERTLIIVEDGASVDYVEGCTAPNYS
SDSLHAAVVEVNVEPNAYCRYTTIQNWSDNVYSLETKRAAAAENATMEWVDGNLGSKVTMKYPSVYLNGEGARGTMLSIA
VASNGIHQDSGARMIHNAKNTSSSIVSKSIAKTGGATDYRGTVRFAKHSDGSKAHVECDTIIMDDQSSSNTIPYNEIDSA
NVAMEHEAKVSKISEEQLYYLMSRGISEAKATEMIIMGFVEPFTKQLPMEYAVELNRLISFEMEGSIG

Sequences:

>Translated_468_residues
MSEVPDVVKNDRDYEYGFHDDVKPAYSTGRGLTEATVREISAAKHEPQWMLDYRLNAYHEYLKMPMPKFGPDLTKLDLKD
MLYYQKMTDKKFRDWKEVPADLKRTFDRLGVPEAERKYLAGSSAQYESEVVYHNMRKDFEKLGIIFTDTDTALHDYPELF
KKWFGKLVKPTDNKFAALNAAVWSGGSFIYVPKGVQTKTPIQSYFRLNAENSGQFERTLIIVEDGASVDYVEGCTAPNYS
SDSLHAAVVEVNVEPNAYCRYTTIQNWSDNVYSLETKRAAAAENATMEWVDGNLGSKVTMKYPSVYLNGEGARGTMLSIA
VASNGIHQDSGARMIHNAKNTSSSIVSKSIAKTGGATDYRGTVRFAKHSDGSKAHVECDTIIMDDQSSSNTIPYNEIDSA
NVAMEHEAKVSKISEEQLYYLMSRGISEAKATEMIIMGFVEPFTKQLPMEYAVELNRLISFEMEGSIG
>Mature_467_residues
SEVPDVVKNDRDYEYGFHDDVKPAYSTGRGLTEATVREISAAKHEPQWMLDYRLNAYHEYLKMPMPKFGPDLTKLDLKDM
LYYQKMTDKKFRDWKEVPADLKRTFDRLGVPEAERKYLAGSSAQYESEVVYHNMRKDFEKLGIIFTDTDTALHDYPELFK
KWFGKLVKPTDNKFAALNAAVWSGGSFIYVPKGVQTKTPIQSYFRLNAENSGQFERTLIIVEDGASVDYVEGCTAPNYSS
DSLHAAVVEVNVEPNAYCRYTTIQNWSDNVYSLETKRAAAAENATMEWVDGNLGSKVTMKYPSVYLNGEGARGTMLSIAV
ASNGIHQDSGARMIHNAKNTSSSIVSKSIAKTGGATDYRGTVRFAKHSDGSKAHVECDTIIMDDQSSSNTIPYNEIDSAN
VAMEHEAKVSKISEEQLYYLMSRGISEAKATEMIIMGFVEPFTKQLPMEYAVELNRLISFEMEGSIG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=461, Percent_Identity=39.9132321041215, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1787971, Length=239, Percent_Identity=26.3598326359833, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 52588; Mature: 52456

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVPDVVKNDRDYEYGFHDDVKPAYSTGRGLTEATVREISAAKHEPQWMLDYRLNAYHE
CCCCCHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHH
YLKMPMPKFGPDLTKLDLKDMLYYQKMTDKKFRDWKEVPADLKRTFDRLGVPEAERKYLA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHC
GSSAQYESEVVYHNMRKDFEKLGIIFTDTDTALHDYPELFKKWFGKLVKPTDNKFAALNA
CCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEH
AVWSGGSFIYVPKGVQTKTPIQSYFRLNAENSGQFERTLIIVEDGASVDYVEGCTAPNYS
EEECCCCEEEECCCCCCCCCHHHHHEECCCCCCCEEEEEEEEECCCCCCHHCCCCCCCCC
SDSLHAAVVEVNVEPNAYCRYTTIQNWSDNVYSLETKRAAAAENATMEWVDGNLGSKVTM
CCCEEEEEEEEECCCCCEEEEEEECCCCCCEEEEEHHHHHHHCCCEEEEECCCCCCEEEE
KYPSVYLNGEGARGTMLSIAVASNGIHQDSGARMIHNAKNTSSSIVSKSIAKTGGATDYR
ECCEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCC
GTVRFAKHSDGSKAHVECDTIIMDDQSSSNTIPYNEIDSANVAMEHEAKVSKISEEQLYY
CEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
LMSRGISEAKATEMIIMGFVEPFTKQLPMEYAVELNRLISFEMEGSIG
HHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCC
>Mature Secondary Structure 
SEVPDVVKNDRDYEYGFHDDVKPAYSTGRGLTEATVREISAAKHEPQWMLDYRLNAYHE
CCCCHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHH
YLKMPMPKFGPDLTKLDLKDMLYYQKMTDKKFRDWKEVPADLKRTFDRLGVPEAERKYLA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHC
GSSAQYESEVVYHNMRKDFEKLGIIFTDTDTALHDYPELFKKWFGKLVKPTDNKFAALNA
CCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEH
AVWSGGSFIYVPKGVQTKTPIQSYFRLNAENSGQFERTLIIVEDGASVDYVEGCTAPNYS
EEECCCCEEEECCCCCCCCCHHHHHEECCCCCCCEEEEEEEEECCCCCCHHCCCCCCCCC
SDSLHAAVVEVNVEPNAYCRYTTIQNWSDNVYSLETKRAAAAENATMEWVDGNLGSKVTM
CCCEEEEEEEEECCCCCEEEEEEECCCCCCEEEEEHHHHHHHCCCEEEEECCCCCCEEEE
KYPSVYLNGEGARGTMLSIAVASNGIHQDSGARMIHNAKNTSSSIVSKSIAKTGGATDYR
ECCEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCC
GTVRFAKHSDGSKAHVECDTIIMDDQSSSNTIPYNEIDSANVAMEHEAKVSKISEEQLYY
CEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
LMSRGISEAKATEMIIMGFVEPFTKQLPMEYAVELNRLISFEMEGSIG
HHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]