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The map label for this gene is mnaA [H]

Identifier: 28377947

GI number: 28377947

Start: 1069688

End: 1070806

Strand: Direct

Name: mnaA [H]

Synonym: lp_1173

Alternate gene names: 28377947

Gene position: 1069688-1070806 (Clockwise)

Preceding gene: 28377946

Following gene: 28377948

Centisome position: 32.33

GC content: 51.21

Gene sequence:

>1119_bases
ATGACAAAACCAATTAAGGTAATGACGATTTTCGGCACGCGGCCAGAAGCAATTAAGATGGCGCCCATCGTGTTGCAGTT
GCAGCAACAGCCACAATTTGAACCGGTAACGGTGGTGACGGCTCAACACCGCGAGATGTTAGACCAGGTGCTCACGATTT
TTCACATTACGCCGGACTATGATTTGAATATCATGAAGCCTAATCAGACGTTAGCTGGTATCACCAGCCGGGTACTGACG
AAGTTAGATGCAATTATGGATACAGTCAAGCCTGATATCGTGCTGGTGCATGGTGATACAACCACGACGTTTGCAGCTAG
TGTGAGTGCTTTTTATCATCAAATCCCAGTCGGACACGTGGAAGCGGGGTTGCGGACGTGGCAGAAGTACTCGCCATATC
CTGAAGAGATGAATCGGCAGCTGACCGATGTGCTGGCCGACATGTACTTTGCACCGACCGAATTAAGTCGGCAGAATCTA
TTGAAGGAAAACCATCCGGATACGGCCATCACGGTAACGGGCAATACGGCCATCGATGCCCTAAAACAGACGGTTTCGAT
GGACTATCAACACGCTGCACTTGATTTGATTCAGCCTGGGCACCGGATGATCTTACTCACGATGCATCGGCGTGAGAATC
AGGGCGCCCCGATGGAAGCGGTCTTTGTCGCCATCAAACGAGTGGTTGCTCAGCATCCCGATGTCGAAGTGGTCTACCCA
GTACACTTGAGTCCGGCAGTGCAGACAGTCGCTAAACGTATCCTCGGCCATACCGATCGCATTCACCTCATTGACCCGCT
CGACGTGCTTGATTTCCACAACATGGCGGCGCGCAGTTACTTCATTATGACGGATTCGGGTGGGGTGCAGGAAGAAGCCC
CGTCACTGAATAAACCGGTGCTCGTATTGCGTGATACTACTGAACGACCGGAAGGGGTCACCGCGGGGACGTTACGATTA
GTCGGCACTGATGGTCAGCAGGTTGCGGCAGCGATGACCAGCCTGTTAGATGATTCCGCAGCGTACCAACGGATGGCAGA
CGCTAAAAATCCTTATGGCGATGGTCATGCTGCGGAATACATCTTACAAGCGATTATGAAAAAAAATGGTACACATTAA

Upstream 100 bases:

>100_bases
GAATCCTTGAAAATAACTAAACTTTTACTCGAAATGATGGCGCCACGACGTAACTAACGCTATGATGAGATTAGAAACTA
AATGATGCAGGTGAAAGTTA

Downstream 100 bases:

>100_bases
AATTATTTACATTTTTGTATAAACAGTGTAATATTAAGCACTGACATAGTGATAAAAATTTTCACTTCTCCTGTAAAGAT
GTGAAATTAGTGAAGTAGCC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTKPIKVMTIFGTRPEAIKMAPIVLQLQQQPQFEPVTVVTAQHREMLDQVLTIFHITPDYDLNIMKPNQTLAGITSRVLT
KLDAIMDTVKPDIVLVHGDTTTTFAASVSAFYHQIPVGHVEAGLRTWQKYSPYPEEMNRQLTDVLADMYFAPTELSRQNL
LKENHPDTAITVTGNTAIDALKQTVSMDYQHAALDLIQPGHRMILLTMHRRENQGAPMEAVFVAIKRVVAQHPDVEVVYP
VHLSPAVQTVAKRILGHTDRIHLIDPLDVLDFHNMAARSYFIMTDSGGVQEEAPSLNKPVLVLRDTTERPEGVTAGTLRL
VGTDGQQVAAAMTSLLDDSAAYQRMADAKNPYGDGHAAEYILQAIMKKNGTH

Sequences:

>Translated_372_residues
MTKPIKVMTIFGTRPEAIKMAPIVLQLQQQPQFEPVTVVTAQHREMLDQVLTIFHITPDYDLNIMKPNQTLAGITSRVLT
KLDAIMDTVKPDIVLVHGDTTTTFAASVSAFYHQIPVGHVEAGLRTWQKYSPYPEEMNRQLTDVLADMYFAPTELSRQNL
LKENHPDTAITVTGNTAIDALKQTVSMDYQHAALDLIQPGHRMILLTMHRRENQGAPMEAVFVAIKRVVAQHPDVEVVYP
VHLSPAVQTVAKRILGHTDRIHLIDPLDVLDFHNMAARSYFIMTDSGGVQEEAPSLNKPVLVLRDTTERPEGVTAGTLRL
VGTDGQQVAAAMTSLLDDSAAYQRMADAKNPYGDGHAAEYILQAIMKKNGTH
>Mature_371_residues
TKPIKVMTIFGTRPEAIKMAPIVLQLQQQPQFEPVTVVTAQHREMLDQVLTIFHITPDYDLNIMKPNQTLAGITSRVLTK
LDAIMDTVKPDIVLVHGDTTTTFAASVSAFYHQIPVGHVEAGLRTWQKYSPYPEEMNRQLTDVLADMYFAPTELSRQNLL
KENHPDTAITVTGNTAIDALKQTVSMDYQHAALDLIQPGHRMILLTMHRRENQGAPMEAVFVAIKRVVAQHPDVEVVYPV
HLSPAVQTVAKRILGHTDRIHLIDPLDVLDFHNMAARSYFIMTDSGGVQEEAPSLNKPVLVLRDTTERPEGVTAGTLRLV
GTDGQQVAAAMTSLLDDSAAYQRMADAKNPYGDGHAAEYILQAIMKKNGTH

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=373, Percent_Identity=56.8364611260054, Blast_Score=396, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41269; Mature: 41138

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIKVMTIFGTRPEAIKMAPIVLQLQQQPQFEPVTVVTAQHREMLDQVLTIFHITPDY
CCCCEEEEEEECCCCCCEEHHHHHEEECCCCCCCCEEEEEHHHHHHHHHHHHHEECCCCC
DLNIMKPNQTLAGITSRVLTKLDAIMDTVKPDIVLVHGDTTTTFAASVSAFYHQIPVGHV
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHH
EAGLRTWQKYSPYPEEMNRQLTDVLADMYFAPTELSRQNLLKENHPDTAITVTGNTAIDA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCHHHHH
LKQTVSMDYQHAALDLIQPGHRMILLTMHRRENQGAPMEAVFVAIKRVVAQHPDVEVVYP
HHHHHHCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEE
VHLSPAVQTVAKRILGHTDRIHLIDPLDVLDFHNMAARSYFIMTDSGGVQEEAPSLNKPV
ECCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCE
LVLRDTTERPEGVTAGTLRLVGTDGQQVAAAMTSLLDDSAAYQRMADAKNPYGDGHAAEY
EEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
ILQAIMKKNGTH
HHHHHHHHCCCC
>Mature Secondary Structure 
TKPIKVMTIFGTRPEAIKMAPIVLQLQQQPQFEPVTVVTAQHREMLDQVLTIFHITPDY
CCCEEEEEEECCCCCCEEHHHHHEEECCCCCCCCEEEEEHHHHHHHHHHHHHEECCCCC
DLNIMKPNQTLAGITSRVLTKLDAIMDTVKPDIVLVHGDTTTTFAASVSAFYHQIPVGHV
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHH
EAGLRTWQKYSPYPEEMNRQLTDVLADMYFAPTELSRQNLLKENHPDTAITVTGNTAIDA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCHHHHH
LKQTVSMDYQHAALDLIQPGHRMILLTMHRRENQGAPMEAVFVAIKRVVAQHPDVEVVYP
HHHHHHCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEE
VHLSPAVQTVAKRILGHTDRIHLIDPLDVLDFHNMAARSYFIMTDSGGVQEEAPSLNKPV
ECCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCE
LVLRDTTERPEGVTAGTLRLVGTDGQQVAAAMTSLLDDSAAYQRMADAKNPYGDGHAAEY
EEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
ILQAIMKKNGTH
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]