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The map label for this gene is citC [H]

Identifier: 28377894

GI number: 28377894

Start: 1004384

End: 1005439

Strand: Direct

Name: citC [H]

Synonym: lp_1106

Alternate gene names: 28377894

Gene position: 1004384-1005439 (Clockwise)

Preceding gene: 28377893

Following gene: 28377895

Centisome position: 30.36

GC content: 48.96

Gene sequence:

>1056_bases
ATGGCAGCGCAAGTTGTTGAAATGCAATTAAATAATCCGCACGAGCATGCCCAGTGGCAACAATTCTTAACGTCATTAGG
GATTACTAATTTTAGCCCGCAAGAGGTTGAACATATTGATGTGACCTTAGGATTGATCGAGGATGGCCAACTTGTTGGGA
CCGGATCGTTAGCTGGCAACGTGCTTAAATATGTGGGTGTCTGTAATAAGAATAGTCAGCCGGGGGCCCGGTTTAATCAA
ATCGTGAGTGCACTGGTCAATCGGCTGTTTCAAGCACAGATCTTTCATATGATGGTATTTACCAAGGCCAAGTATTCAGC
GAGTTTTCAACACGTAGGCTTTAAAGAATTAGCTCATTCGGATGAAGCGGCCGTATTAGAAAACGGCGCACCGGATATGA
CGGATTTTGTCAAACAGTTGCCGATGATTCCCAACCAAGCACAACAGCGTGTCAGCGCGATTGTCATGAATGCGAACCCG
TTTACGCGGGGACACCGCTATTTAGTGGAACAAGCCGCGGCGGTCAGTGATTTAGTTTACGTCTTCGTCGTTGCGACAGA
TGCGAGTCTATTCCGTACGGCCGAGCGCGTTAAGCTGGTTCAACAAGGAACAGCCGACTTGGCCAACGTTCGGATCGTCA
GCGGGCAGGACTATCTCGTGAGTGCAGCGACCTTTCCAGCCTACTTCTTGGATTCAGCGGCGAGCGCAATTGAGGCGCAG
ACGACGTTGGACGCCCGGATCTTTAAGCAGCAACTTGCACCAGCACTGCACATTACGACCCGGTTCGTTGGTAGTGAACC
GACGTCGCGGACGACTGCGATTTATAACCGAGTTTTGCAGCGTGAATTACCACCGGCAGTTGCTGTACGAGTGATATCGC
GAACGACGGTGGCTAATCAACCAATTTCGGCGCGGACTGTTCGGCAACGGATTCGAAGCGGCAACTTAACTGAGTTAAAC
CAACTGGTACCGGCAACAACGGCCCAGTTTATAAAAAATAACCTAACAACATTACAAGCGCGAATTCAGAAAGGAATGAA
AATTGATGGAAATTAA

Upstream 100 bases:

>100_bases
CGATTGTGCCGAGCGTCTTTGATTCACAAGTGGTACCGAACGTGACGGCGGCCGTTGCAGCGTACGCGCAAGCACAGCAT
TAATCATAGGAGGTTGTCTG

Downstream 100 bases:

>100_bases
GACAACGGCAGTCGCCGGAACCTTGGAATCATCTGATATTCAAATTATGTTAATGGCGGGAGACAACGGCATTCAAATCG
ACCTTGAATCGGATGTTATC

Product: [citrate (pro-3S)-lyase] ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAAQVVEMQLNNPHEHAQWQQFLTSLGITNFSPQEVEHIDVTLGLIEDGQLVGTGSLAGNVLKYVGVCNKNSQPGARFNQ
IVSALVNRLFQAQIFHMMVFTKAKYSASFQHVGFKELAHSDEAAVLENGAPDMTDFVKQLPMIPNQAQQRVSAIVMNANP
FTRGHRYLVEQAAAVSDLVYVFVVATDASLFRTAERVKLVQQGTADLANVRIVSGQDYLVSAATFPAYFLDSAASAIEAQ
TTLDARIFKQQLAPALHITTRFVGSEPTSRTTAIYNRVLQRELPPAVAVRVISRTTVANQPISARTVRQRIRSGNLTELN
QLVPATTAQFIKNNLTTLQARIQKGMKIDGN

Sequences:

>Translated_351_residues
MAAQVVEMQLNNPHEHAQWQQFLTSLGITNFSPQEVEHIDVTLGLIEDGQLVGTGSLAGNVLKYVGVCNKNSQPGARFNQ
IVSALVNRLFQAQIFHMMVFTKAKYSASFQHVGFKELAHSDEAAVLENGAPDMTDFVKQLPMIPNQAQQRVSAIVMNANP
FTRGHRYLVEQAAAVSDLVYVFVVATDASLFRTAERVKLVQQGTADLANVRIVSGQDYLVSAATFPAYFLDSAASAIEAQ
TTLDARIFKQQLAPALHITTRFVGSEPTSRTTAIYNRVLQRELPPAVAVRVISRTTVANQPISARTVRQRIRSGNLTELN
QLVPATTAQFIKNNLTTLQARIQKGMKIDGN
>Mature_350_residues
AAQVVEMQLNNPHEHAQWQQFLTSLGITNFSPQEVEHIDVTLGLIEDGQLVGTGSLAGNVLKYVGVCNKNSQPGARFNQI
VSALVNRLFQAQIFHMMVFTKAKYSASFQHVGFKELAHSDEAAVLENGAPDMTDFVKQLPMIPNQAQQRVSAIVMNANPF
TRGHRYLVEQAAAVSDLVYVFVVATDASLFRTAERVKLVQQGTADLANVRIVSGQDYLVSAATFPAYFLDSAASAIEAQT
TLDARIFKQQLAPALHITTRFVGSEPTSRTTAIYNRVLQRELPPAVAVRVISRTTVANQPISARTVRQRIRSGNLTELNQ
LVPATTAQFIKNNLTTLQARIQKGMKIDGN

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081765, Length=304, Percent_Identity=35.8552631578947, Blast_Score=201, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 38534; Mature: 38402

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQVVEMQLNNPHEHAQWQQFLTSLGITNFSPQEVEHIDVTLGLIEDGQLVGTGSLAGN
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEEECCCEEECCHHHHH
VLKYVGVCNKNSQPGARFNQIVSALVNRLFQAQIFHMMVFTKAKYSASFQHVGFKELAHS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCC
DEAAVLENGAPDMTDFVKQLPMIPNQAQQRVSAIVMNANPFTRGHRYLVEQAAAVSDLVY
CCHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
VFVVATDASLFRTAERVKLVQQGTADLANVRIVSGQDYLVSAATFPAYFLDSAASAIEAQ
HHHEECCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
TTLDARIFKQQLAPALHITTRFVGSEPTSRTTAIYNRVLQRELPPAVAVRVISRTTVANQ
HHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PISARTVRQRIRSGNLTELNQLVPATTAQFIKNNLTTLQARIQKGMKIDGN
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AAQVVEMQLNNPHEHAQWQQFLTSLGITNFSPQEVEHIDVTLGLIEDGQLVGTGSLAGN
CCEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEEECCCEEECCHHHHH
VLKYVGVCNKNSQPGARFNQIVSALVNRLFQAQIFHMMVFTKAKYSASFQHVGFKELAHS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHCC
DEAAVLENGAPDMTDFVKQLPMIPNQAQQRVSAIVMNANPFTRGHRYLVEQAAAVSDLVY
CCHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
VFVVATDASLFRTAERVKLVQQGTADLANVRIVSGQDYLVSAATFPAYFLDSAASAIEAQ
HHHEECCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
TTLDARIFKQQLAPALHITTRFVGSEPTSRTTAIYNRVLQRELPPAVAVRVISRTTVANQ
HHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PISARTVRQRIRSGNLTELNQLVPATTAQFIKNNLTTLQARIQKGMKIDGN
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]