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The map label for this gene is hpaG [C]

Identifier: 28377759

GI number: 28377759

Start: 861714

End: 862544

Strand: Direct

Name: hpaG [C]

Synonym: lp_0931

Alternate gene names: 28377759

Gene position: 861714-862544 (Clockwise)

Preceding gene: 28377758

Following gene: 28377760

Centisome position: 26.05

GC content: 49.46

Gene sequence:

>831_bases
GTGTACAATAATATTAATGAGGTGATTAATATGAAAATTGGCATGCGGGCCAACCGACCGTTTATCATTACGGATGAACA
GCATGGACAAACAGTTTTAAATGCGAAGACAGTTTTGGAAGCACTACATACACCTGCAGCGGACCGACAACTTGGCTCGC
TTGAAACGTTTGCGCCGCAAGAATTAGCGGCACCAATCACGGCCCCACGACAGATTTTTGCGGTGGGGATGAACTACCGT
GACCATTCGGCGGAGATCCACATTACGCTGCCGAAGGTTCCAAGTATTTTTACGAAGTTTAGTAGTTCACTGGCACCAGC
GAACGTGACCATGGCGACGCATGGTCCTGAGACCGACTGGGAAACCGAGCTAGTCGTGATGATTGGCAAGGGTGGGCGCG
ATATCGCGACGGCTGATGCAATGGCGCACGTGGCCGGAGTGATGGTTGGTGAAGACTTATCTGATCGAGCCGTTCAGTTC
GAGAATGATAATCCACAGTTTTCAATAGGTAAATCGTTTGAAAATTACGCACCAGTTGGGCCGTGGTTAACGACCGTCGA
TGAGTTAGCTAACTTAGACGATGAGGTGATCACGACCACCGTCAATGGTCAGACGATGCAGCAAGCGCCGTTGAGCCAAC
TGATCTTCAAGGTACCGGATTTGGTACACTACTTGTCGACGGTCTGTGAGTTACAACCAGGTGATTTGATTTTTACCGGG
ACGCCTAGTGGGACCGGCGTTGGTCGCAATCCCCAAGTCTTTTTGCAAGCCGGCGATCAACTGTGCGGTCAAATCACGCA
TTTAGGAACACTGAATATCACGATTAAGTAA

Upstream 100 bases:

>100_bases
AATATCCTGAGCTAAGTTCGTAATTGCGTTTGAACGTTCATAAAGATTGTCCGGAATGACCGTCACGCAACTATCATTAT
TGTTATGATTCATGAGATGA

Downstream 100 bases:

>100_bases
ATAGCCATAGTCGGTAAGTGTGGCGGGTGAAGGTTTATATTATAACGCCCAGCACAGTACCGACTTTTTTGGTACCATGG
GATTAGTAATTAAATAGGGG

Product: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioatedecarboxylase (putative)

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MYNNINEVINMKIGMRANRPFIITDEQHGQTVLNAKTVLEALHTPAADRQLGSLETFAPQELAAPITAPRQIFAVGMNYR
DHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPETDWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQF
ENDNPQFSIGKSFENYAPVGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTG
TPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK

Sequences:

>Translated_276_residues
MYNNINEVINMKIGMRANRPFIITDEQHGQTVLNAKTVLEALHTPAADRQLGSLETFAPQELAAPITAPRQIFAVGMNYR
DHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPETDWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQF
ENDNPQFSIGKSFENYAPVGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTG
TPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK
>Mature_276_residues
MYNNINEVINMKIGMRANRPFIITDEQHGQTVLNAKTVLEALHTPAADRQLGSLETFAPQELAAPITAPRQIFAVGMNYR
DHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPETDWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQF
ENDNPQFSIGKSFENYAPVGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTG
TPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=210, Percent_Identity=43.3333333333333, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI40786394, Length=210, Percent_Identity=42.8571428571429, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI215422413, Length=181, Percent_Identity=31.4917127071823, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI66348062, Length=181, Percent_Identity=31.4917127071823, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI13654274, Length=181, Percent_Identity=31.4917127071823, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=28.2051282051282, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=32.9608938547486, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324161, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28572127, Length=215, Percent_Identity=39.0697674418605, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24663695, Length=213, Percent_Identity=34.2723004694836, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=31.0344827586207, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29909; Mature: 29909

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNNINEVINMKIGMRANRPFIITDEQHGQTVLNAKTVLEALHTPAADRQLGSLETFAPQ
CCCCHHHHEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
ELAAPITAPRQIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPETDW
HHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCC
ETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAPVG
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCCCCCCCC
PWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
TPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK
CCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEEEEC
>Mature Secondary Structure
MYNNINEVINMKIGMRANRPFIITDEQHGQTVLNAKTVLEALHTPAADRQLGSLETFAPQ
CCCCHHHHEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
ELAAPITAPRQIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATHGPETDW
HHCCCCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCC
ETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAPVG
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCCCCCCCC
PWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIFTG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
TPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK
CCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA