Click here to switch to the map view.

The map label for this gene is mtnU [H]

Identifier: 28377336

GI number: 28377336

Start: 386606

End: 387382

Strand: Direct

Name: mtnU [H]

Synonym: lp_0433

Alternate gene names: 28377336

Gene position: 386606-387382 (Clockwise)

Preceding gene: 28377334

Following gene: 28377337

Centisome position: 11.69

GC content: 49.55

Gene sequence:

>777_bases
ATGCATGTCGCACTAGCACAACTTAATATTCAGTTTGGAGATCCGGATGCCAACTACGAGCAGATTGAAATGGCCATTCA
ACGGGCAGCTGAGCAAACTGTCGACGTGATCGTCTTACCGGAGATGTGGAATACCGGTTATGCGTTAACTCGCCTGAATG
TCTTGGCGGATGATGATGGGCAGCGAACGTTACAATTACTCAGCAAGTTAGCTCAGCAGTTTTGCGTCAACATTGTCGGT
GGCTCAGTCGCGGTCGCTCGCGATGGGCATTACTATAATGAGATGTTAGTCGTCGATCGTCAGGGACAGTTACTGAGTCG
TTACGATAAAGTCCACCGGTTTGGGTTAATGGCGGAAGACCGTTATATTACTGCTGGTGAGACCGAGAACGTTTTTGAAC
TCGACGGAACTGTTGCGATGGGGGCGATTTGTTATGACATTCGTTTCCCAGAATGGCTTCGTAAACAAGCAGCTCGTGGC
CCCCAAGTGATTTTTTTCAGTGCTGAGTGGCCGACAGTGCGGCAGATGCAATGGCGGCTATTACTGCAAGCACGTGCGAT
TGAAAATCAAGCATTCGTGGTTGCGGTTAACCGCGTTGGCAGTGATCCTGATAATCAATTTGGTGGTCAGTCACTAGTTA
TTGACCCGCTCGGCCAAATTGTGGCTATCGGTGGTGCCCATGCCCAGTTGATTACGGCCGAGCTTGATTTAACACAAGTT
GACCAGGTTCGTGGTCAGATTCCAGTGTTTGAAGACCGGCGCCCGGAATTATACTGA

Upstream 100 bases:

>100_bases
GGCAAGTTCGGCAGCCTTACGATGGCAAGGCTGAAACTTGCAACCTATGACTATTTATTCTAATATGATTTTAATCATTC
TAATAAAGTGGGTGGAACGA

Downstream 100 bases:

>100_bases
AGCGTAAATTGGGGACTGGGGCTGGGAGCACTTAACTGAATTTTAATGGTGTTGAAGGAACGCCCGCTTGAATTTCGATG
GGCTTAAACGTCGAAATGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MHVALAQLNIQFGDPDANYEQIEMAIQRAAEQTVDVIVLPEMWNTGYALTRLNVLADDDGQRTLQLLSKLAQQFCVNIVG
GSVAVARDGHYYNEMLVVDRQGQLLSRYDKVHRFGLMAEDRYITAGETENVFELDGTVAMGAICYDIRFPEWLRKQAARG
PQVIFFSAEWPTVRQMQWRLLLQARAIENQAFVVAVNRVGSDPDNQFGGQSLVIDPLGQIVAIGGAHAQLITAELDLTQV
DQVRGQIPVFEDRRPELY

Sequences:

>Translated_258_residues
MHVALAQLNIQFGDPDANYEQIEMAIQRAAEQTVDVIVLPEMWNTGYALTRLNVLADDDGQRTLQLLSKLAQQFCVNIVG
GSVAVARDGHYYNEMLVVDRQGQLLSRYDKVHRFGLMAEDRYITAGETENVFELDGTVAMGAICYDIRFPEWLRKQAARG
PQVIFFSAEWPTVRQMQWRLLLQARAIENQAFVVAVNRVGSDPDNQFGGQSLVIDPLGQIVAIGGAHAQLITAELDLTQV
DQVRGQIPVFEDRRPELY
>Mature_258_residues
MHVALAQLNIQFGDPDANYEQIEMAIQRAAEQTVDVIVLPEMWNTGYALTRLNVLADDDGQRTLQLLSKLAQQFCVNIVG
GSVAVARDGHYYNEMLVVDRQGQLLSRYDKVHRFGLMAEDRYITAGETENVFELDGTVAMGAICYDIRFPEWLRKQAARG
PQVIFFSAEWPTVRQMQWRLLLQARAIENQAFVVAVNRVGSDPDNQFGGQSLVIDPLGQIVAIGGAHAQLITAELDLTQV
DQVRGQIPVFEDRRPELY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=28.8389513108614, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI297632350, Length=178, Percent_Identity=32.0224719101124, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI297632348, Length=178, Percent_Identity=32.0224719101124, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5031947, Length=178, Percent_Identity=32.0224719101124, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1786412, Length=255, Percent_Identity=34.9019607843137, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17556280, Length=274, Percent_Identity=31.7518248175182, Blast_Score=120, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6323383, Length=276, Percent_Identity=29.3478260869565, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=26.578073089701, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355835, Length=272, Percent_Identity=31.6176470588235, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17933642, Length=270, Percent_Identity=28.8888888888889, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28978; Mature: 28978

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVALAQLNIQFGDPDANYEQIEMAIQRAAEQTVDVIVLPEMWNTGYALTRLNVLADDDG
CEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEEEEEEEECCCC
QRTLQLLSKLAQQFCVNIVGGSVAVARDGHYYNEMLVVDRQGQLLSRYDKVHRFGLMAED
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECEEEEEECCCHHHHHHHHHHHHCCEECC
RYITAGETENVFELDGTVAMGAICYDIRFPEWLRKQAARGPQVIFFSAEWPTVRQMQWRL
CEEECCCCCCEEEECCCEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
LLQARAIENQAFVVAVNRVGSDPDNQFGGQSLVIDPLGQIVAIGGAHAQLITAELDLTQV
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEEEEECCHHHH
DQVRGQIPVFEDRRPELY
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHVALAQLNIQFGDPDANYEQIEMAIQRAAEQTVDVIVLPEMWNTGYALTRLNVLADDDG
CEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEEEEEEEECCCC
QRTLQLLSKLAQQFCVNIVGGSVAVARDGHYYNEMLVVDRQGQLLSRYDKVHRFGLMAED
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECEEEEEECCCHHHHHHHHHHHHCCEECC
RYITAGETENVFELDGTVAMGAICYDIRFPEWLRKQAARGPQVIFFSAEWPTVRQMQWRL
CEEECCCCCCEEEECCCEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
LLQARAIENQAFVVAVNRVGSDPDNQFGGQSLVIDPLGQIVAIGGAHAQLITAELDLTQV
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEEEEECCHHHH
DQVRGQIPVFEDRRPELY
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]