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The map label for this gene is ywaC [H]

Identifier: 28377216

GI number: 28377216

Start: 265061

End: 265753

Strand: Direct

Name: ywaC [H]

Synonym: lp_0293

Alternate gene names: 28377216

Gene position: 265061-265753 (Clockwise)

Preceding gene: 28377215

Following gene: 28377218

Centisome position: 8.01

GC content: 43.29

Gene sequence:

>693_bases
TTGAGCACAACAAATTCCCAAGCAAGTGCAGATAATGATCAGCTTTTGCCAGCACCCCCGGAACTTTTGCAAGCTGTTGA
TCAGTTGAAAGCTTATTCGTTACGTTATGAAGTTGCGATGAAGCTCGTTTTAGATAAGTTAGATTATATTAGTCGAGAGT
ATGAGCTTCGTTACGGCTACGCGTTAATTGATAGCAAGCAGTCCCGGATCAAGTCGCCTGAGAGCATTGTTGGTAAGATG
CAACGTAAGCATTTACCGTTAACGTTAAATGCGGTGTTTAATAATTTGCATGATATTGCGGGTATCCGGTTGATTGTTCG
TTTCCTAAGCGATGTCAAGACAGTCGAGAATTTATTGGCGACTCAGGCTGACATTAAAGTATTACGAGTGAAGGATTATA
TTCATCATCCTAAAGCTAATGGCTATCAGAGTTTGCATTTAATCCTCGGGGTGCCGGTCTACACTGTTGATGGGCCGAGC
ATCATTGAGGTCGAACTACAAGTACGGACGATTGCCATGAACTTTTGGGCGTCGTTGGAGCATGAATTAAATTATAAGAA
GAACGTTCCGCATCAGGACGCATTGCGAGCGTCATTGACTAAGAAGGCGCAGTTAATTACGGAGCTGGATCAGGAAATGG
ACGATATCAAGCAACGGATGTATGAACCTAAGACGCCCCCAAAAGAAGTCTAA

Upstream 100 bases:

>100_bases
CGCACCAAATTGCGTATGACCAAATTGCGCGTGAGTGGACCATCACGATCCGTTAAGGTAGATTGAGAGAGAATAGAGTC
TTATATTGGAGCGATATTGA

Downstream 100 bases:

>100_bases
AAAATGCCCGATTATTAGCAGGTAATTGCTAATAATCGGGCATTTTGGGGTTTTCTTGACGCGAATCAAGTCCATCCATG
CACATGACTGGTATCTTATA

Product: GTP pyrophosphokinase (putative)

Products: NA

Alternate protein names: (p)ppGpp synthase ywaC; Small alarmone synthase 2; SAS 2 [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSTTNSQASADNDQLLPAPPELLQAVDQLKAYSLRYEVAMKLVLDKLDYISREYELRYGYALIDSKQSRIKSPESIVGKM
QRKHLPLTLNAVFNNLHDIAGIRLIVRFLSDVKTVENLLATQADIKVLRVKDYIHHPKANGYQSLHLILGVPVYTVDGPS
IIEVELQVRTIAMNFWASLEHELNYKKNVPHQDALRASLTKKAQLITELDQEMDDIKQRMYEPKTPPKEV

Sequences:

>Translated_230_residues
MSTTNSQASADNDQLLPAPPELLQAVDQLKAYSLRYEVAMKLVLDKLDYISREYELRYGYALIDSKQSRIKSPESIVGKM
QRKHLPLTLNAVFNNLHDIAGIRLIVRFLSDVKTVENLLATQADIKVLRVKDYIHHPKANGYQSLHLILGVPVYTVDGPS
IIEVELQVRTIAMNFWASLEHELNYKKNVPHQDALRASLTKKAQLITELDQEMDDIKQRMYEPKTPPKEV
>Mature_229_residues
STTNSQASADNDQLLPAPPELLQAVDQLKAYSLRYEVAMKLVLDKLDYISREYELRYGYALIDSKQSRIKSPESIVGKMQ
RKHLPLTLNAVFNNLHDIAGIRLIVRFLSDVKTVENLLATQADIKVLRVKDYIHHPKANGYQSLHLILGVPVYTVDGPSI
IEVELQVRTIAMNFWASLEHELNYKKNVPHQDALRASLTKKAQLITELDQEMDDIKQRMYEPKTPPKEV

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in respo

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 26278; Mature: 26146

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTNSQASADNDQLLPAPPELLQAVDQLKAYSLRYEVAMKLVLDKLDYISREYELRYGY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALIDSKQSRIKSPESIVGKMQRKHLPLTLNAVFNNLHDIAGIRLIVRFLSDVKTVENLLA
CEECCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQADIKVLRVKDYIHHPKANGYQSLHLILGVPVYTVDGPSIIEVELQVRTIAMNFWASLE
HHHHHHHHHHHHHHCCCCCCCHHHEEHEEECEEEEECCCCEEEEEEEHHHHHHHHHHHHH
HELNYKKNVPHQDALRASLTKKAQLITELDQEMDDIKQRMYEPKTPPKEV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STTNSQASADNDQLLPAPPELLQAVDQLKAYSLRYEVAMKLVLDKLDYISREYELRYGY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALIDSKQSRIKSPESIVGKMQRKHLPLTLNAVFNNLHDIAGIRLIVRFLSDVKTVENLLA
CEECCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQADIKVLRVKDYIHHPKANGYQSLHLILGVPVYTVDGPSIIEVELQVRTIAMNFWASLE
HHHHHHHHHHHHHHCCCCCCCHHHEEHEEECEEEEECCCCEEEEEEEHHHHHHHHHHHHH
HELNYKKNVPHQDALRASLTKKAQLITELDQEMDDIKQRMYEPKTPPKEV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]