Click here to switch to the map view.

The map label for this gene is agl1 [H]

Identifier: 28377114

GI number: 28377114

Start: 149293

End: 150966

Strand: Direct

Name: agl1 [H]

Synonym: lp_0174

Alternate gene names: 28377114

Gene position: 149293-150966 (Clockwise)

Preceding gene: 28377113

Following gene: 28377115

Centisome position: 4.51

GC content: 46.36

Gene sequence:

>1674_bases
ATGAGCAAGCATTGGTATGATCAACAAACGATTTATCAAATATATCCTAAGAGTTTTAACGATAGTAATCACGATGGCAT
TGGTGATATTCCGGGAATTACCGCGAAGATTCCCTATTTGAAGCAACTTGGGATTACCACGATATGGTTAAACCCAATTT
ATCAATCACCCCAGGTTGATAATGGCTACGATGTTTCGGATTACTACCAAGTTGATTCGAGCTTAGGGACCATGACGGAC
GTTGAGACGCTCATTAAAACGGTCCATGAGCACGGCATGTATCTTATCTTTGACTTTGTCTTGAATCATACTTCAGATCA
GCATCCATGGTTCAAGCAAGCTCTCGCTGATCCACAGAGTAAGTATCGGGACTACTATTTATGGCAAGATCCCGCAGCCG
ATGGTGGGCGCCCAAACAACTGGGGCTCATTTTTCGGTGGCAGTGTTTGGGCGAAGGATCCGGCAGGCGGCTCACAGTAT
TATTTCCACTTGTTTGATAAACGGATGCCGGACCTCAATTGGAAGAATCCGGCAGTGCAACAGGCGATGCGTGATGTTGC
TGAGTTTTGGGTTGAAAAGGGGATTGATGGTCTCCGGTTAGATGCGTTTATTCATCTGGCTAAAGCAGATTTTCGCCAAA
CTTATCCAAATCGGACTGGTGATTCGACACCCATCATTAGCGATATGTTTTATGCCCACTTACCGAAAGTGCATCAGTAC
TTACACGACTTTGTCGCCGTAATCAAAGCTAAGCACCCGGATACGTACGTCGTCGGTGAAGCGTCATCCGCTGACCCCCA
TTTGATGGTCGACTATACGACACCAGGTACGGATGAGTGTGATCAAGTGATTACGTTCAGAACTTTTGCGGACGACAATA
CCCAGGATGATCCGAGCTTCTCCGACACATTTCAGCCCCGACCGATGGATGTGACGGCCTATAAGCAAAATACGGTCGGT
ATTCAAGCGGCTTTAGCAGACACCAGTCTACCAACACTTTACTGGAATAATCATGATATGGCTCGGGTCGCCACGCGTTA
CGGTGATCCTGATTATCCGCAAGCAAGTGCCAAGGCGTTAGCGACGGCCCTGTATTTGCAGCGTGGCATTCCCATTATTT
ATTATGGGGAAGAATTAGGATTAACAAATATCCGTTATCATGATATTGCGGACTTTGAAGACCAGACGGTACCCACCTTT
GTTGCGAGCGCTCAAGCCGCTGGTAAGTCTAAGGTGGAAATCATGCGGATGTTGAATCAAACTCATAAAATGGCGGGGCG
CGGCCCCATGCAATGGGACAATACGGTTTATCATGGTTTCTCTGACCACTTACCATGGAAACATGGTGATACTGATGACA
TGAATGCGCAAGCAGAAATCGCTGACCCCGACAGTATTTATCACTATTATCAACAGTTGCTGCAGCTAAAGCAGTGCGCA
CCCTTTACTAATGGTCAGTTCATTATGCTCGGAAGTGCTGAACAACTCTTTACCTACCTCATTGATGATGGTCAAAAACA
AGCAGCGATAGTTTGTAATTTAAGTGCGCAAGCGCAAACGTATCTGTTGCCGTTTGTTGGTGGTAAAGTGTTGCTTGTAC
AGGGTGGTGCAACATATAGGGGACGCCAAGTGACGTTACCAGCTTGGAGTAGCTTAGTCGTTAAATCGGCATAA

Upstream 100 bases:

>100_bases
CATACTGATCGTTCTCGCGGGCGGCATGATCAAGAAAAAATCATCATTAATTCACGGTTGTCGGTGGCTGAATCGACCCG
TTAAAGAGGAGTCTGGATAG

Downstream 100 bases:

>100_bases
GCAATGTGAGTGCATGATTATCCTAAAATTGGTATATATAAATCATGTGATGTATTTTAATTAACTTATCAATCTTTATA
TAAATTGGTATAAAGGTTGA

Product: alpha-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MSKHWYDQQTIYQIYPKSFNDSNHDGIGDIPGITAKIPYLKQLGITTIWLNPIYQSPQVDNGYDVSDYYQVDSSLGTMTD
VETLIKTVHEHGMYLIFDFVLNHTSDQHPWFKQALADPQSKYRDYYLWQDPAADGGRPNNWGSFFGGSVWAKDPAGGSQY
YFHLFDKRMPDLNWKNPAVQQAMRDVAEFWVEKGIDGLRLDAFIHLAKADFRQTYPNRTGDSTPIISDMFYAHLPKVHQY
LHDFVAVIKAKHPDTYVVGEASSADPHLMVDYTTPGTDECDQVITFRTFADDNTQDDPSFSDTFQPRPMDVTAYKQNTVG
IQAALADTSLPTLYWNNHDMARVATRYGDPDYPQASAKALATALYLQRGIPIIYYGEELGLTNIRYHDIADFEDQTVPTF
VASAQAAGKSKVEIMRMLNQTHKMAGRGPMQWDNTVYHGFSDHLPWKHGDTDDMNAQAEIADPDSIYHYYQQLLQLKQCA
PFTNGQFIMLGSAEQLFTYLIDDGQKQAAIVCNLSAQAQTYLLPFVGGKVLLVQGGATYRGRQVTLPAWSSLVVKSA

Sequences:

>Translated_557_residues
MSKHWYDQQTIYQIYPKSFNDSNHDGIGDIPGITAKIPYLKQLGITTIWLNPIYQSPQVDNGYDVSDYYQVDSSLGTMTD
VETLIKTVHEHGMYLIFDFVLNHTSDQHPWFKQALADPQSKYRDYYLWQDPAADGGRPNNWGSFFGGSVWAKDPAGGSQY
YFHLFDKRMPDLNWKNPAVQQAMRDVAEFWVEKGIDGLRLDAFIHLAKADFRQTYPNRTGDSTPIISDMFYAHLPKVHQY
LHDFVAVIKAKHPDTYVVGEASSADPHLMVDYTTPGTDECDQVITFRTFADDNTQDDPSFSDTFQPRPMDVTAYKQNTVG
IQAALADTSLPTLYWNNHDMARVATRYGDPDYPQASAKALATALYLQRGIPIIYYGEELGLTNIRYHDIADFEDQTVPTF
VASAQAAGKSKVEIMRMLNQTHKMAGRGPMQWDNTVYHGFSDHLPWKHGDTDDMNAQAEIADPDSIYHYYQQLLQLKQCA
PFTNGQFIMLGSAEQLFTYLIDDGQKQAAIVCNLSAQAQTYLLPFVGGKVLLVQGGATYRGRQVTLPAWSSLVVKSA
>Mature_556_residues
SKHWYDQQTIYQIYPKSFNDSNHDGIGDIPGITAKIPYLKQLGITTIWLNPIYQSPQVDNGYDVSDYYQVDSSLGTMTDV
ETLIKTVHEHGMYLIFDFVLNHTSDQHPWFKQALADPQSKYRDYYLWQDPAADGGRPNNWGSFFGGSVWAKDPAGGSQYY
FHLFDKRMPDLNWKNPAVQQAMRDVAEFWVEKGIDGLRLDAFIHLAKADFRQTYPNRTGDSTPIISDMFYAHLPKVHQYL
HDFVAVIKAKHPDTYVVGEASSADPHLMVDYTTPGTDECDQVITFRTFADDNTQDDPSFSDTFQPRPMDVTAYKQNTVGI
QAALADTSLPTLYWNNHDMARVATRYGDPDYPQASAKALATALYLQRGIPIIYYGEELGLTNIRYHDIADFEDQTVPTFV
ASAQAAGKSKVEIMRMLNQTHKMAGRGPMQWDNTVYHGFSDHLPWKHGDTDDMNAQAEIADPDSIYHYYQQLLQLKQCAP
FTNGQFIMLGSAEQLFTYLIDDGQKQAAIVCNLSAQAQTYLLPFVGGKVLLVQGGATYRGRQVTLPAWSSLVVKSA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=548, Percent_Identity=29.9270072992701, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI1790687, Length=536, Percent_Identity=35.8208955223881, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1786604, Length=369, Percent_Identity=24.1192411924119, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32565753, Length=205, Percent_Identity=29.7560975609756, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25147709, Length=485, Percent_Identity=23.5051546391753, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322245, Length=577, Percent_Identity=29.6360485268631, Blast_Score=256, Evalue=5e-69,
Organism=Saccharomyces cerevisiae, GI6322241, Length=547, Percent_Identity=30.8957952468007, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6322021, Length=547, Percent_Identity=30.8957952468007, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321726, Length=547, Percent_Identity=30.3473491773309, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6324416, Length=547, Percent_Identity=30.8957952468007, Blast_Score=246, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6321731, Length=564, Percent_Identity=31.9148936170213, Blast_Score=243, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6319776, Length=564, Percent_Identity=31.9148936170213, Blast_Score=243, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24583747, Length=534, Percent_Identity=33.8951310861423, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24583749, Length=534, Percent_Identity=33.8951310861423, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24583745, Length=517, Percent_Identity=33.0754352030948, Blast_Score=246, Evalue=4e-65,
Organism=Drosophila melanogaster, GI45549022, Length=540, Percent_Identity=30.5555555555556, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24586597, Length=527, Percent_Identity=31.3092979127135, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24586591, Length=522, Percent_Identity=30.8429118773946, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI221330053, Length=509, Percent_Identity=30.2554027504912, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586589, Length=458, Percent_Identity=32.5327510917031, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586599, Length=571, Percent_Identity=28.0210157618214, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586593, Length=507, Percent_Identity=29.9802761341223, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24586587, Length=401, Percent_Identity=32.6683291770574, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI281360393, Length=452, Percent_Identity=26.7699115044248, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 62932; Mature: 62801

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHWYDQQTIYQIYPKSFNDSNHDGIGDIPGITAKIPYLKQLGITTIWLNPIYQSPQVD
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEECCCHHHHCCCEEEEECCCCCCCCCC
NGYDVSDYYQVDSSLGTMTDVETLIKTVHEHGMYLIFDFVLNHTSDQHPWFKQALADPQS
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCHHHHHHCCHHH
KYRDYYLWQDPAADGGRPNNWGSFFGGSVWAKDPAGGSQYYFHLFDKRMPDLNWKNPAVQ
HHCCEEEECCCCCCCCCCCCCCHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCHHHH
QAMRDVAEFWVEKGIDGLRLDAFIHLAKADFRQTYPNRTGDSTPIISDMFYAHLPKVHQY
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LHDFVAVIKAKHPDTYVVGEASSADPHLMVDYTTPGTDECDQVITFRTFADDNTQDDPSF
HHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHEEEEEEECCCCCCCCCCC
SDTFQPRPMDVTAYKQNTVGIQAALADTSLPTLYWNNHDMARVATRYGDPDYPQASAKAL
CCCCCCCCCEEEEECCCCCEEEEEECCCCCCEEEECCCCHHHHHHHCCCCCCCCHHHHHH
ATALYLQRGIPIIYYGEELGLTNIRYHDIADFEDQTVPTFVASAQAAGKSKVEIMRMLNQ
HHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
THKMAGRGPMQWDNTVYHGFSDHLPWKHGDTDDMNAQAEIADPDSIYHYYQQLLQLKQCA
HHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCC
PFTNGQFIMLGSAEQLFTYLIDDGQKQAAIVCNLSAQAQTYLLPFVGGKVLLVQGGATYR
CCCCCCEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCCC
GRQVTLPAWSSLVVKSA
CCEEECCCCCCEEEECC
>Mature Secondary Structure 
SKHWYDQQTIYQIYPKSFNDSNHDGIGDIPGITAKIPYLKQLGITTIWLNPIYQSPQVD
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEECCCHHHHCCCEEEEECCCCCCCCCC
NGYDVSDYYQVDSSLGTMTDVETLIKTVHEHGMYLIFDFVLNHTSDQHPWFKQALADPQS
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCHHHHHHCCHHH
KYRDYYLWQDPAADGGRPNNWGSFFGGSVWAKDPAGGSQYYFHLFDKRMPDLNWKNPAVQ
HHCCEEEECCCCCCCCCCCCCCHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCHHHH
QAMRDVAEFWVEKGIDGLRLDAFIHLAKADFRQTYPNRTGDSTPIISDMFYAHLPKVHQY
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LHDFVAVIKAKHPDTYVVGEASSADPHLMVDYTTPGTDECDQVITFRTFADDNTQDDPSF
HHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHEEEEEEECCCCCCCCCCC
SDTFQPRPMDVTAYKQNTVGIQAALADTSLPTLYWNNHDMARVATRYGDPDYPQASAKAL
CCCCCCCCCEEEEECCCCCEEEEEECCCCCCEEEECCCCHHHHHHHCCCCCCCCHHHHHH
ATALYLQRGIPIIYYGEELGLTNIRYHDIADFEDQTVPTFVASAQAAGKSKVEIMRMLNQ
HHHHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
THKMAGRGPMQWDNTVYHGFSDHLPWKHGDTDDMNAQAEIADPDSIYHYYQQLLQLKQCA
HHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCC
PFTNGQFIMLGSAEQLFTYLIDDGQKQAAIVCNLSAQAQTYLLPFVGGKVLLVQGGATYR
CCCCCCEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCCC
GRQVTLPAWSSLVVKSA
CCEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]