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The map label for this gene is rrp1 [H]

Identifier: 28377004

GI number: 28377004

Start: 37770

End: 38477

Strand: Direct

Name: rrp1 [H]

Synonym: lp_0036

Alternate gene names: 28377004

Gene position: 37770-38477 (Clockwise)

Preceding gene: 28377003

Following gene: 28377005

Centisome position: 1.14

GC content: 45.76

Gene sequence:

>708_bases
ATGAAAAAAATCTTAGTAGTTGATGATGAAAAGCCCATCTCTGATATCATGAAATTTAATCTGACCAAAGAAGGCTATGA
AGTTCACGTTGCAGCTGACGGAGAGGAAGCCTTACAAAAAGTGGATGAAGTCCACCCTGATTTGATTTTGTTAGATTTGA
TGTTGCCTAAGATGGATGGCTTGGAAGTTGCTCGACAAGTACGGAAGAACTATGATATGCCAATTATCATGGTAACGGCA
AAGGACTCTGAATTAGACAAGGTGTTGGGCTTGGAACTGGGCGCGGACGACTATGTGACCAAACCGTTCTCAAACCGGGA
ACTCGTGGCTCGAGTCAAAGCAAATCTGCGGCGGCAAGGTACACCAAGTGCCCAACCAGCTGAAGTTGAAGAAAATTCAG
ACATTGAAATTGGCGATCTGGTGATTCATCCAGAAGCTTATATGGTTTCCAAACGCGGTGAAAACATCGAATTAACGCAC
CGTGAATTTGAACTGTTACATTACTTAGCCCAACATATCGGCCAAGTCATGACGCGGGAACACTTGTTGCAGACGGTCTG
GGGCTATGATTACTTTGGTGATGTCCGGACAGTTGATGTGACCGTGCGGCGGTTACGTGAAAAAGTTGAAGATAACCCGA
GTCATCCAAAATGGCTGGTGACGCGGCGGGGCGTGGGTTACTATCTCCGCAATCCTGAAAATGAGTAG

Upstream 100 bases:

>100_bases
AACCCTGACACGAGAAAGGACCTGTTTTCTCGTAATATATCGCGAATCACCCTAAAAATTGAAATGTAAACCTGTTTTCC
CCTAAGGAGGAAGAATCGTT

Downstream 100 bases:

>100_bases
AGGTTGCTAAACCGTGTTGAGATTTAAACGGAAAAATTTTTTTAAAACAATTAATTTCAAAATTGCGCTCGTGTTTGCCC
TTCTATTATTGATTACGTTG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKKILVVDDEKPISDIMKFNLTKEGYEVHVAADGEEALQKVDEVHPDLILLDLMLPKMDGLEVARQVRKNYDMPIIMVTA
KDSELDKVLGLELGADDYVTKPFSNRELVARVKANLRRQGTPSAQPAEVEENSDIEIGDLVIHPEAYMVSKRGENIELTH
REFELLHYLAQHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSHPKWLVTRRGVGYYLRNPENE

Sequences:

>Translated_235_residues
MKKILVVDDEKPISDIMKFNLTKEGYEVHVAADGEEALQKVDEVHPDLILLDLMLPKMDGLEVARQVRKNYDMPIIMVTA
KDSELDKVLGLELGADDYVTKPFSNRELVARVKANLRRQGTPSAQPAEVEENSDIEIGDLVIHPEAYMVSKRGENIELTH
REFELLHYLAQHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSHPKWLVTRRGVGYYLRNPENE
>Mature_235_residues
MKKILVVDDEKPISDIMKFNLTKEGYEVHVAADGEEALQKVDEVHPDLILLDLMLPKMDGLEVARQVRKNYDMPIIMVTA
KDSELDKVLGLELGADDYVTKPFSNRELVARVKANLRRQGTPSAQPAEVEENSDIEIGDLVIHPEAYMVSKRGENIELTH
REFELLHYLAQHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSHPKWLVTRRGVGYYLRNPENE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=44.9781659388646, Blast_Score=173, Evalue=7e-45,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=42.3580786026201, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.961038961039, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=40.7079646017699, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=38.2222222222222, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=36.1233480176211, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=37.8723404255319, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.4763948497854, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=36.2068965517241, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=33.7606837606838, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=30.7017543859649, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.5991189427313, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=34.7107438016529, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=35.7142857142857, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=113, Percent_Identity=30.9734513274336, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.0877192982456, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=111, Percent_Identity=36.9369369369369, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27061; Mature: 27061

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVVDDEKPISDIMKFNLTKEGYEVHVAADGEEALQKVDEVHPDLILLDLMLPKMDG
CCEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEHHCCCCCH
LEVARQVRKNYDMPIIMVTAKDSELDKVLGLELGADDYVTKPFSNRELVARVKANLRRQG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
TPSAQPAEVEENSDIEIGDLVIHPEAYMVSKRGENIELTHREFELLHYLAQHIGQVMTRE
CCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSHPKWLVTRRGVGYYLRNPENE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCC
>Mature Secondary Structure
MKKILVVDDEKPISDIMKFNLTKEGYEVHVAADGEEALQKVDEVHPDLILLDLMLPKMDG
CCEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEHHCCCCCH
LEVARQVRKNYDMPIIMVTAKDSELDKVLGLELGADDYVTKPFSNRELVARVKANLRRQG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
TPSAQPAEVEENSDIEIGDLVIHPEAYMVSKRGENIELTHREFELLHYLAQHIGQVMTRE
CCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSHPKWLVTRRGVGYYLRNPENE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]