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The map label for this gene is glgP [H]

Identifier: 28376996

GI number: 28376996

Start: 26753

End: 29149

Strand: Direct

Name: glgP [H]

Synonym: lp_0024

Alternate gene names: 28376996

Gene position: 26753-29149 (Clockwise)

Preceding gene: 28376995

Following gene: 28376997

Centisome position: 0.81

GC content: 47.98

Gene sequence:

>2397_bases
TTGAAATTAACGTGTGCGCAATTTAAAAAGGACTTTCTAAGTGAAATTGAGACCTTGTATTCAACATCGCTGAGTGACAC
CTCGACGATTGGGCAATTTATTGCACTGGGACAGCTAGTTCGGCGCTATAACAGTCAGAGTTGGACACGAACAGCTAAAT
TTTACCGCGATCATCATCAGAAACAAGTCTATTATTTTTCCATCGAGTTCTTGCCGGGACGCTTACTCGCTTCTAATTTG
TTGAATCTCAACTTATTGACGACTGTAAAAAAAGGGCTAACGGAATTGGGCTTAGACTTTGAGACAATCAGTCAGGCTGA
ACCTGATCCGGCGCTTGGTAACGGAGGATTAGGTCGGTTGGCAGCCTGCTATATGGACGCGATGGCTAGTTTGAAGATTG
CTGGCAACGGTAACGGCATCCGCTATCGTTACGGCTTGTTCAAACAAGTTTTCATGGATGGCTATCAAGTAGAATTACCC
GATGATTGGCTCCATCATGGCAACGTGTGGGAGACCCGGCGCGATAACAAGAGCTGCATTGTCCAGTTCGGCGGCAATGT
GTGGTTACAACCGCAAGCGGATGGTAGTTTACAACCGCAATCTGAAAATACGGAAGACGTGCTAGCGGTTCCTTACGACG
TTGGTATCGTCGGGTATCACAACGATATTACGAACACCTTGCGTTTGTGGTCCGCGGAGTTACCACCCAGTGCGACCTAT
TCTTCGCAGGATCAGCGTGATCGAATCAGTGAGATTACCAAGGTCTTGTATCCTGACGATTCTAACTCGGCCGGGCAACA
ACTGCGTTTACGCCAAGAATACTTTTTCTCTTCTGCGGGTGTTCAAAGTATCGTGCGTGATTTTTGTGCGACGCACCATG
GCATCAAATTGTTAGGCAAAAAGGTCGCGATTCACATTAACGATACGCACCCGACGCTGGTGATCCCTGAGATGATGCGG
CTATTAATGGATGAACATCACTGTTCATGGGAAGTTGCGTGGACGTTAACGACGCAAGTCATGAGTTACACGAACCATAC
GATTTTACAAGAGGCCCTCGAGACTTGGCCAATCGATATGTTTAAAAACCTGCTACCCCGGATCTATCAGATTATTGCGG
AAATCGACCGGCGCTACCGGGAACAACAAACGCCGATTTTTGGCAAAGCGCTCGTTGATCAGACGGCGCCTTTAGGCAAC
GGACAAGTACGGATGGCCTACCTAGCTGTGATTGGGAGTCACAGTGTGAACGGTGTCGCGCCACTGCATACGGAATTACT
GAAAACGGATGTGTTACGGGGCCTGTATCAAGTTTATCCGGAGCGGTTTAATAATAAGACGAATGGCATTGCAACCCGGC
GGTGGGTTCAATTGGCGAACCAACCACTAGCGCAATTGATTGATCAGACGATTGGTTCGGACTGGCGGCGGCAACCAGAT
TTATTACAGACGCTACTGCCGTATCAACAAGATGACCACTTTTTGTACCAGTTAGGTCAAGTTAAACTGACTAACAAGCA
AGCTTTAGCCGCGTACGTTCAGCGTACTATGGGGATCAAGATTCGCACCGACGCGATTTACGATGTTCAAATCAAACGGT
TGCATGCTTATAAGCGGCAACTCCTACACGTCTTTGAAATCTTGCGCGAGTATTTTGCCATTAAGGATCATCCGCAACAG
CCAGTCGTGCCGCGAGTACACATTTTCGGTGCCAAGGCGGCTCCTAGTTATCACTATGCCAAGGCGATTATCAAACTCAT
TAATGTCGTCGCTGACATGGTGAATCAGGACCCGGCGATTGGTGATCGGTTAAAGATCGTCTTTATTCCGAACTACGGGG
TCTCCATTGCCGAACTGATCATTCCCGCCGCCGACGTTAGCGAGCAGATTTCAACGGCCTCCAAAGAAGCGTCGGGGACT
AGTAACATGAAACTGATGGCCAACGGTGCATTATCATTGGCAACGTATGACGGCGCGAATATCGACATTATGCAAGCGGC
GGGTGCTGAAAATGAATATCCGTTTGGGCTTAAGGTCAATGAAGTGTACGACTATTACCATCGCGGCAACTATCACGCCG
CTGACTTTTACGATGCTGATCCTGAATTAAAACGGCTCTTAGATAGTTTGATTGATGGCACGATTCCGGGAATTCCAACG
GTTGGTCGGGAAATCTATGATTCATTACTGCGGTATAATGATGAATTCTTTGTCTTAGCCGATTACCGGGCTTATGTCAC
CCAACAACAGCAGATCAGTCGTGATTTTCAAAATCAACCCACTTGGCAACAACGCTCGTTAGCCAACATTGCCGCTTCGG
GACACTTTGCCGCGGACTTAGCAGTGGCGCGGTATGCTGACGATATTTGGCAAGTGCCCCACGAACGACTGAATTAA

Upstream 100 bases:

>100_bases
CACCAAGCAATGACTTGTGATTTTGGCTGGGAACATTCTGCACAGCAGTACCGTGCGACTTATCAGAAGCTAATGCGTTA
GGTTTGATGGGGGTGTGAAT

Downstream 100 bases:

>100_bases
GAAAGGAAGGGTGACGGATGCAGGTAACGTATAACTCATTTTTACCCACGTATAAGACACCCTTTGGTGCCGTGACCCGC
CAGACACCCGTTCAATTCAC

Product: glycogen phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 798; Mature: 798

Protein sequence:

>798_residues
MKLTCAQFKKDFLSEIETLYSTSLSDTSTIGQFIALGQLVRRYNSQSWTRTAKFYRDHHQKQVYYFSIEFLPGRLLASNL
LNLNLLTTVKKGLTELGLDFETISQAEPDPALGNGGLGRLAACYMDAMASLKIAGNGNGIRYRYGLFKQVFMDGYQVELP
DDWLHHGNVWETRRDNKSCIVQFGGNVWLQPQADGSLQPQSENTEDVLAVPYDVGIVGYHNDITNTLRLWSAELPPSATY
SSQDQRDRISEITKVLYPDDSNSAGQQLRLRQEYFFSSAGVQSIVRDFCATHHGIKLLGKKVAIHINDTHPTLVIPEMMR
LLMDEHHCSWEVAWTLTTQVMSYTNHTILQEALETWPIDMFKNLLPRIYQIIAEIDRRYREQQTPIFGKALVDQTAPLGN
GQVRMAYLAVIGSHSVNGVAPLHTELLKTDVLRGLYQVYPERFNNKTNGIATRRWVQLANQPLAQLIDQTIGSDWRRQPD
LLQTLLPYQQDDHFLYQLGQVKLTNKQALAAYVQRTMGIKIRTDAIYDVQIKRLHAYKRQLLHVFEILREYFAIKDHPQQ
PVVPRVHIFGAKAAPSYHYAKAIIKLINVVADMVNQDPAIGDRLKIVFIPNYGVSIAELIIPAADVSEQISTASKEASGT
SNMKLMANGALSLATYDGANIDIMQAAGAENEYPFGLKVNEVYDYYHRGNYHAADFYDADPELKRLLDSLIDGTIPGIPT
VGREIYDSLLRYNDEFFVLADYRAYVTQQQQISRDFQNQPTWQQRSLANIAASGHFAADLAVARYADDIWQVPHERLN

Sequences:

>Translated_798_residues
MKLTCAQFKKDFLSEIETLYSTSLSDTSTIGQFIALGQLVRRYNSQSWTRTAKFYRDHHQKQVYYFSIEFLPGRLLASNL
LNLNLLTTVKKGLTELGLDFETISQAEPDPALGNGGLGRLAACYMDAMASLKIAGNGNGIRYRYGLFKQVFMDGYQVELP
DDWLHHGNVWETRRDNKSCIVQFGGNVWLQPQADGSLQPQSENTEDVLAVPYDVGIVGYHNDITNTLRLWSAELPPSATY
SSQDQRDRISEITKVLYPDDSNSAGQQLRLRQEYFFSSAGVQSIVRDFCATHHGIKLLGKKVAIHINDTHPTLVIPEMMR
LLMDEHHCSWEVAWTLTTQVMSYTNHTILQEALETWPIDMFKNLLPRIYQIIAEIDRRYREQQTPIFGKALVDQTAPLGN
GQVRMAYLAVIGSHSVNGVAPLHTELLKTDVLRGLYQVYPERFNNKTNGIATRRWVQLANQPLAQLIDQTIGSDWRRQPD
LLQTLLPYQQDDHFLYQLGQVKLTNKQALAAYVQRTMGIKIRTDAIYDVQIKRLHAYKRQLLHVFEILREYFAIKDHPQQ
PVVPRVHIFGAKAAPSYHYAKAIIKLINVVADMVNQDPAIGDRLKIVFIPNYGVSIAELIIPAADVSEQISTASKEASGT
SNMKLMANGALSLATYDGANIDIMQAAGAENEYPFGLKVNEVYDYYHRGNYHAADFYDADPELKRLLDSLIDGTIPGIPT
VGREIYDSLLRYNDEFFVLADYRAYVTQQQQISRDFQNQPTWQQRSLANIAASGHFAADLAVARYADDIWQVPHERLN
>Mature_798_residues
MKLTCAQFKKDFLSEIETLYSTSLSDTSTIGQFIALGQLVRRYNSQSWTRTAKFYRDHHQKQVYYFSIEFLPGRLLASNL
LNLNLLTTVKKGLTELGLDFETISQAEPDPALGNGGLGRLAACYMDAMASLKIAGNGNGIRYRYGLFKQVFMDGYQVELP
DDWLHHGNVWETRRDNKSCIVQFGGNVWLQPQADGSLQPQSENTEDVLAVPYDVGIVGYHNDITNTLRLWSAELPPSATY
SSQDQRDRISEITKVLYPDDSNSAGQQLRLRQEYFFSSAGVQSIVRDFCATHHGIKLLGKKVAIHINDTHPTLVIPEMMR
LLMDEHHCSWEVAWTLTTQVMSYTNHTILQEALETWPIDMFKNLLPRIYQIIAEIDRRYREQQTPIFGKALVDQTAPLGN
GQVRMAYLAVIGSHSVNGVAPLHTELLKTDVLRGLYQVYPERFNNKTNGIATRRWVQLANQPLAQLIDQTIGSDWRRQPD
LLQTLLPYQQDDHFLYQLGQVKLTNKQALAAYVQRTMGIKIRTDAIYDVQIKRLHAYKRQLLHVFEILREYFAIKDHPQQ
PVVPRVHIFGAKAAPSYHYAKAIIKLINVVADMVNQDPAIGDRLKIVFIPNYGVSIAELIIPAADVSEQISTASKEASGT
SNMKLMANGALSLATYDGANIDIMQAAGAENEYPFGLKVNEVYDYYHRGNYHAADFYDADPELKRLLDSLIDGTIPGIPT
VGREIYDSLLRYNDEFFVLADYRAYVTQQQQISRDFQNQPTWQQRSLANIAASGHFAADLAVARYADDIWQVPHERLN

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI71037379, Length=815, Percent_Identity=42.0858895705521, Blast_Score=618, Evalue=1e-177,
Organism=Homo sapiens, GI5032009, Length=819, Percent_Identity=40.6593406593407, Blast_Score=616, Evalue=1e-176,
Organism=Homo sapiens, GI21361370, Length=785, Percent_Identity=42.5477707006369, Blast_Score=609, Evalue=1e-174,
Organism=Homo sapiens, GI255653002, Length=698, Percent_Identity=42.9799426934097, Blast_Score=581, Evalue=1e-165,
Organism=Homo sapiens, GI257900462, Length=669, Percent_Identity=41.5545590433483, Blast_Score=540, Evalue=1e-153,
Organism=Escherichia coli, GI2367228, Length=777, Percent_Identity=44.2728442728443, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=750, Percent_Identity=40.9333333333333, Blast_Score=569, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI32566204, Length=786, Percent_Identity=42.6208651399491, Blast_Score=634, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=786, Percent_Identity=42.6208651399491, Blast_Score=633, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=840, Percent_Identity=38.0952380952381, Blast_Score=531, Evalue=1e-151,
Organism=Drosophila melanogaster, GI78706832, Length=812, Percent_Identity=41.6256157635468, Blast_Score=630, Evalue=1e-180,
Organism=Drosophila melanogaster, GI24581010, Length=812, Percent_Identity=41.6256157635468, Blast_Score=630, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 90523; Mature: 90523

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTCAQFKKDFLSEIETLYSTSLSDTSTIGQFIALGQLVRRYNSQSWTRTAKFYRDHHQ
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
KQVYYFSIEFLPGRLLASNLLNLNLLTTVKKGLTELGLDFETISQAEPDPALGNGGLGRL
CEEEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHH
AACYMDAMASLKIAGNGNGIRYRYGLFKQVFMDGYQVELPDDWLHHGNVWETRRDNKSCI
HHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHCCCEEECCHHHHHCCCCCCCCCCCCEEE
VQFGGNVWLQPQADGSLQPQSENTEDVLAVPYDVGIVGYHNDITNTLRLWSAELPPSATY
EEECCCEEEECCCCCCCCCCCCCCCCEEEEEEECEEEEECCHHHHHHHHHCCCCCCCCCC
SSQDQRDRISEITKVLYPDDSNSAGQQLRLRQEYFFSSAGVQSIVRDFCATHHGIKLLGK
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECC
KVAIHINDTHPTLVIPEMMRLLMDEHHCSWEVAWTLTTQVMSYTNHTILQEALETWPIDM
EEEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHH
FKNLLPRIYQIIAEIDRRYREQQTPIFGKALVDQTAPLGNGQVRMAYLAVIGSHSVNGVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCC
PLHTELLKTDVLRGLYQVYPERFNNKTNGIATRRWVQLANQPLAQLIDQTIGSDWRRQPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHH
LLQTLLPYQQDDHFLYQLGQVKLTNKQALAAYVQRTMGIKIRTDAIYDVQIKRLHAYKRQ
HHHHHCCCCCCCHHHHHCCCEEECCHHHHHHHHHHHCCCEEEECCEEHHHHHHHHHHHHH
LLHVFEILREYFAIKDHPQQPVVPRVHIFGAKAAPSYHYAKAIIKLINVVADMVNQDPAI
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GDRLKIVFIPNYGVSIAELIIPAADVSEQISTASKEASGTSNMKLMANGALSLATYDGAN
CCCEEEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCC
IDIMQAAGAENEYPFGLKVNEVYDYYHRGNYHAADFYDADPELKRLLDSLIDGTIPGIPT
EEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCH
VGREIYDSLLRYNDEFFVLADYRAYVTQQQQISRDFQNQPTWQQRSLANIAASGHFAADL
HHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHH
AVARYADDIWQVPHERLN
HHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MKLTCAQFKKDFLSEIETLYSTSLSDTSTIGQFIALGQLVRRYNSQSWTRTAKFYRDHHQ
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
KQVYYFSIEFLPGRLLASNLLNLNLLTTVKKGLTELGLDFETISQAEPDPALGNGGLGRL
CEEEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHH
AACYMDAMASLKIAGNGNGIRYRYGLFKQVFMDGYQVELPDDWLHHGNVWETRRDNKSCI
HHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHCCCEEECCHHHHHCCCCCCCCCCCCEEE
VQFGGNVWLQPQADGSLQPQSENTEDVLAVPYDVGIVGYHNDITNTLRLWSAELPPSATY
EEECCCEEEECCCCCCCCCCCCCCCCEEEEEEECEEEEECCHHHHHHHHHCCCCCCCCCC
SSQDQRDRISEITKVLYPDDSNSAGQQLRLRQEYFFSSAGVQSIVRDFCATHHGIKLLGK
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECC
KVAIHINDTHPTLVIPEMMRLLMDEHHCSWEVAWTLTTQVMSYTNHTILQEALETWPIDM
EEEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHH
FKNLLPRIYQIIAEIDRRYREQQTPIFGKALVDQTAPLGNGQVRMAYLAVIGSHSVNGVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCC
PLHTELLKTDVLRGLYQVYPERFNNKTNGIATRRWVQLANQPLAQLIDQTIGSDWRRQPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHH
LLQTLLPYQQDDHFLYQLGQVKLTNKQALAAYVQRTMGIKIRTDAIYDVQIKRLHAYKRQ
HHHHHCCCCCCCHHHHHCCCEEECCHHHHHHHHHHHCCCEEEECCEEHHHHHHHHHHHHH
LLHVFEILREYFAIKDHPQQPVVPRVHIFGAKAAPSYHYAKAIIKLINVVADMVNQDPAI
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GDRLKIVFIPNYGVSIAELIIPAADVSEQISTASKEASGTSNMKLMANGALSLATYDGAN
CCCEEEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCC
IDIMQAAGAENEYPFGLKVNEVYDYYHRGNYHAADFYDADPELKRLLDSLIDGTIPGIPT
EEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCH
VGREIYDSLLRYNDEFFVLADYRAYVTQQQQISRDFQNQPTWQQRSLANIAASGHFAADL
HHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHH
AVARYADDIWQVPHERLN
HHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8145641; 9387221; 9384377 [H]