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The map label for this gene is sdaAA [H]

Identifier: 28211607

GI number: 28211607

Start: 2109136

End: 2110008

Strand: Direct

Name: sdaAA [H]

Synonym: CTC01982

Alternate gene names: 28211607

Gene position: 2109136-2110008 (Clockwise)

Preceding gene: 28211606

Following gene: 28211609

Centisome position: 75.35

GC content: 36.08

Gene sequence:

>873_bases
TTGTTTGTTAATACTGGTTTAGAGTTAATAGATATATGTAAGGAAAAAAATCTAAAAATATGGGAATATGGATTAAATGT
AGAACTTGAAGAAACTGGGGAAACCAAAGATTTCTTAATAGATAAAATGAACAAAACACTTCAAGTAATGAAACAATCTG
CCAACTTAGGTCTAGAAAAAGAAGTTAAATCCGTAAGTGGTCTCATTGGTGGAGATGCCTATAAATTAAATAAATATTCA
GAAGATAAAAACACATTAACAGGTTCTCTCATAGTTAAAGCTATGGCTAGAGCATTGTCTTCTTCTGAAGTAAATGCTGC
CATGGGTAAAATTGTGGCTTGTCCCACTGCTGGTTCTTGTGGTATATTACCTGCTGCATTAATCTCTGCTGGTGAAGCAT
TAAATAAATCAGATGAAGATTTAGTTAATGCATTATTTACCGCTTCAGTTGTAGGAGTTATAATAGCTAAGAATGCTACC
TTAGCAGGTGCTGAAGGAGGATGTCAAGCTGAATGTGGCTCTGCTGCTGCTATGGCCGCAGCTTCCATTGTAGAACTTAT
GGGCGGAACTGTTGATCAATCTTTAGATGCAGCTGCTATAGTTATAAAGAACATATTAGGATTAGTCTGTGACCCTGTAG
CAGGTCTTGTAGAAATACCTTGTGCTAAAAGAAATGCCGCTGGTGTTGTAAGTGCTCTTACCTCTGCTGATATGGTTATG
GCTGGTGTTAAAAGTGCTATACCTTTTGATGATACAGTTTTAGCTATGTATAAAGTGGGTAGACAATTACCTATGGAACT
TAGAGAAACTGCTTTAGGCGGTCTTGCAACAACACCTGCTGGACTTAAATTAAAAAATAAAGTGTTTAAATAA

Upstream 100 bases:

>100_bases
AGATAATGTAATTCCTCAAGCTACTATTGAAAAACTAAAAAAAATTCCAGAAATACATAGTATAAAAATAATAAACCCAA
TGGGGGAAGGAGAGCTTTAA

Downstream 100 bases:

>100_bases
ATGAAAGCATATATTGTGTAAAAATAATTACACAATATATGCTTTTTACCTATTAGTTACTCACTATCCTGTCTCTTCCC
ATTTCTTTTGCATTATACAT

Product: L-serine dehydratase alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MFVNTGLELIDICKEKNLKIWEYGLNVELEETGETKDFLIDKMNKTLQVMKQSANLGLEKEVKSVSGLIGGDAYKLNKYS
EDKNTLTGSLIVKAMARALSSSEVNAAMGKIVACPTAGSCGILPAALISAGEALNKSDEDLVNALFTASVVGVIIAKNAT
LAGAEGGCQAECGSAAAMAAASIVELMGGTVDQSLDAAAIVIKNILGLVCDPVAGLVEIPCAKRNAAGVVSALTSADMVM
AGVKSAIPFDDTVLAMYKVGRQLPMELRETALGGLATTPAGLKLKNKVFK

Sequences:

>Translated_290_residues
MFVNTGLELIDICKEKNLKIWEYGLNVELEETGETKDFLIDKMNKTLQVMKQSANLGLEKEVKSVSGLIGGDAYKLNKYS
EDKNTLTGSLIVKAMARALSSSEVNAAMGKIVACPTAGSCGILPAALISAGEALNKSDEDLVNALFTASVVGVIIAKNAT
LAGAEGGCQAECGSAAAMAAASIVELMGGTVDQSLDAAAIVIKNILGLVCDPVAGLVEIPCAKRNAAGVVSALTSADMVM
AGVKSAIPFDDTVLAMYKVGRQLPMELRETALGGLATTPAGLKLKNKVFK
>Mature_290_residues
MFVNTGLELIDICKEKNLKIWEYGLNVELEETGETKDFLIDKMNKTLQVMKQSANLGLEKEVKSVSGLIGGDAYKLNKYS
EDKNTLTGSLIVKAMARALSSSEVNAAMGKIVACPTAGSCGILPAALISAGEALNKSDEDLVNALFTASVVGVIIAKNAT
LAGAEGGCQAECGSAAAMAAASIVELMGGTVDQSLDAAAIVIKNILGLVCDPVAGLVEIPCAKRNAAGVVSALTSADMVM
AGVKSAIPFDDTVLAMYKVGRQLPMELRETALGGLATTPAGLKLKNKVFK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=181, Percent_Identity=42.5414364640884, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788116, Length=181, Percent_Identity=40.8839779005525, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789161, Length=275, Percent_Identity=34.5454545454545, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30001; Mature: 30001

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVNTGLELIDICKEKNLKIWEYGLNVELEETGETKDFLIDKMNKTLQVMKQSANLGLEK
CCCCCCHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
EVKSVSGLIGGDAYKLNKYSEDKNTLTGSLIVKAMARALSSSEVNAAMGKIVACPTAGSC
HHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEECCCCCCC
GILPAALISAGEALNKSDEDLVNALFTASVVGVIIAKNATLAGAEGGCQAECGSAAAMAA
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH
ASIVELMGGTVDQSLDAAAIVIKNILGLVCDPVAGLVEIPCAKRNAAGVVSALTSADMVM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AGVKSAIPFDDTVLAMYKVGRQLPMELRETALGGLATTPAGLKLKNKVFK
HHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MFVNTGLELIDICKEKNLKIWEYGLNVELEETGETKDFLIDKMNKTLQVMKQSANLGLEK
CCCCCCHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
EVKSVSGLIGGDAYKLNKYSEDKNTLTGSLIVKAMARALSSSEVNAAMGKIVACPTAGSC
HHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEECCCCCCC
GILPAALISAGEALNKSDEDLVNALFTASVVGVIIAKNATLAGAEGGCQAECGSAAAMAA
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH
ASIVELMGGTVDQSLDAAAIVIKNILGLVCDPVAGLVEIPCAKRNAAGVVSALTSADMVM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
AGVKSAIPFDDTVLAMYKVGRQLPMELRETALGGLATTPAGLKLKNKVFK
HHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]