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The map label for this gene is polC

Identifier: 28210957

GI number: 28210957

Start: 1360643

End: 1364926

Strand: Direct

Name: polC

Synonym: CTC01271

Alternate gene names: 28210957

Gene position: 1360643-1364926 (Clockwise)

Preceding gene: 28210956

Following gene: 28210958

Centisome position: 48.61

GC content: 29.39

Gene sequence:

>4284_bases
ATGGAATTAGCTAAAATATTAGAAGACAATACTTTTTCACAAGATAGTTTAGAGGGCATAAGAGTCCATAGAATACAGTA
TTTTAAAAAGAGTAATAAATTGAAGGTTATAGTAAAGTCTAAAAAAGAAGTAAATAATAATCAAATAACTGAAATAAAAA
AGGTGTTTTTTAAAAAATTCCAGTATTTTAAGGAAATAGAAGTGCTTTCTTATAGGGATGTATCTGGAATTAATTTAAAA
GACATATGTGAAAAATATTGGATAGATATAGTAAACAGCATACTTACATATATTCCATTTTGCAAAGAATGTTTAATAAG
TTCAAAAAGGAAAGTAATAGATGAAAACACTTTAAAATTACAATATGGAAATGACTTTTTATATAATATTTTAAAAGAAA
AGAATTTTGAAAAGATACTATCCAGCACCATAAAAGATGTATTTGGAGTAGAGTGTAAAGTAAAATTCATACTGGATAAA
TCCAATGGAAAATGTAATTATTTAGACTTTAAAGAAGAACAGGAAGCCTTAATTATAAAAAATATTATAAAAGAAAGTAG
AATTGAAAAGACCATTCCTAAAAAAGATAACAATTATAATAAAAGGGAAGAAAATAAAAATAGTAGCATAATTGTAGGGA
AAAATATAAATGAAGATCCAGTAGATATATCTAACATAGATGAAACTTCAGGAATTATTTCTATTTGTGGAGATGTGTTT
AAAACAAAGATAATAGAAACTAAAACTGGAAGAAAGATAGTGACCTTTTATATAACAGATTATACAAGTTCTATAACTGT
TAAGTTATTTCCAAAACCTAAAGATACTGAAAGAGTTATAGAGGAAATAAAGGAAGGGTTATATTGTAAAATAAGAGGAG
AAGTAGTAAATGACTCATATGCAAGAGAAATAGTTATAATGGCAAGGGATATAGTAAAACTAAACAAAATTGAAAAAATG
GATATAGCAGAAGAAAAAAGAGTAGAACTTCACCTTCATACAAAGATGAGTGCTATGGATGGAATGAATTCTGCAGAAAG
CTTAATAAAAAGAGCAGCCAAATGGGGACATAAAGCAGTAGCTATTACGGACCATGGCGTGGTTCAGGCATATCCGGAAG
CAATGGAGGCTGCTAAAAAGTACAATATAAAAATAATATATGGTGTAGAGGGTTATTTAGTAGATGATGGGATACCTATA
GCTATAAATGCAGGTCATAGAACTTTAGAGGACAGTTATGTGGTTTTTGACATTGAAACCACTGGTTTTTCTAATAAAAA
TGATAAAATAATAGAAATAGGTGCCGTAAAGATAAAAGAAGGTAAAGTAGTAGATAAATATAGCACTTTTGTCAATCCAG
AAAGAATTATTCCAGAGAAAATAATAGAACTTACAGGAATACATGATTATATGGTAAAGGATGCTCCTAAAATAGAAGAG
GTTTTACCAAAATTTATAGATTTTATTGAAGACTCTATATTAGTTGCTCATAACGCTAATTTTGATGTATCCTTTATAAA
AAAGAACTGTAAGGATTTCGGAATACATTTTAATAATCCAATATTAGATACCATTCCACTTTGTAAATTTTTATATCCTG
AGCTTAAAAGATATAAACTAAATGTGGTAGCAAAACATTTAGGAATACCCCTTTTAAATCATCATAGAGCGGTAGAAGAT
GCTAAAACTACGGGGGATATACTTTTAAAAGCTTTTGAGGATTTAAAAGATAAAGAGATAATGAACTTAAATATGTTAAA
TGAAGAATATTTTAAGAACCAAGATATAAAAAAATCACCTACCTATCATGTAATAATACTAGTTAAAAATAAAATAGGAT
TAAAAAATCTTTATAAACTTATATCTGAATCTCATTTAAATCATTTTTATAAAAAACCAAGAATGCCCAAAAGTCTTATA
AATAAATACAGAGAAGGGCTTATGATAGGATCAGCTTGTGAAGCAGGACAGGTATATAAAGAAGTTTTAATGGATAAATC
CAAAGAAGAATTAAAAGAAGTTATAAGTTTTTATGATTATTTAGAAATACAACCAATAAAGAATAACTATTTTATGATAA
GAAATGGAATAGTAAAAGATGAAGAAGAATTAAGAGATATAAATAAGAAGATATATAATTTAGCAGAAGAAAATAATATG
CCAGTAGTGGCTACTTGTGATGTTCACTTTTTAGATAAAAAAGATGAAGTTTTTAGAAAAATATTAATGGCTGGTCAAGG
ATTTAGCGATGCAGAAAATCAGCCGCCATTATACCTTAGAACTACAGACGAAATGTTAAAAGAATTTGAATATTTAGGAA
AAGAAAAAGCTTACAAGGCTGTTGTTACAAATACAGTAAAAATAGCAGATAGTATAGATAATATAAAACCTATACCCGAT
GAAACCTTTCCTCCAAAAATAGAGGGCTCAGAAGAAGAAGTTAGAAAAATGACTATAGAAAAAGCCCATTCAATATATGG
AGAGGTTTTACCAGAAATAGTAGAAAAAAGATTAGAAAAAGAATTAAATTCTATAATAAATAATGGATATGCGGTACTTT
ATTTAATTGCTCATAAACTAGTGGATAAATCAGTACAAGATGGGTATTTAGTAGGTTCTAGAGGTTCTGTAGGATCTTCC
TTGGTAGCAACTATGACAGATATTACAGAAGTTAATGGTTTGCCTCCACATTATGTTTGCCCTGGATGTAAGTACAATGA
ATTTATAACAGATGGATCTGTGTCTTCAGGAGCGGATCTTCCAGATAAAAACTGTCCTAATTGTGGAGTTTTATTAAGTA
AAGATGGTCACGATATTCCCTTTGAAACCTTTTTAGGTTTTGAAGGAGACAAAGAGCCGGATATAGATTTAAACTTTTCT
GGTGAATATCAAGCAGTAGTTCATAAATATACAGAAGTTCTATTTGGAGAAGGTAAAGTTTTTAAAGCTGGAACCATAGG
AACTATAGCAGAAAAAACTGCTTATGGATTTGTAAAAAAGTATATAAGTGAAAAAGATTTAAATGTAAGACAGGCGGAAA
TTGAGAGACTTACATTAGGATGCAGTGGTGTCAAGAGAACTACAGGACAGCATCCGGGTGGAATAATGGTTGTGCCTCAG
GATAATGAAATATTTAATTTTACACCTATTCAACGTCCAGCAGATGATAATGATACAGATATAATAACTACTCATTTTGA
CTATCATTCAATAAGTGGTAGACTTTTAAAGTTAGATATATTAGGTCATGATGATCCTACTGTATTAAGAATGCTTCAGG
ATTTAACAGGAGTAGATCCTAAAAAAATACCTTTAGCAGATCCAAAAGTAATGAGTTTATTTACCTCACCTAAGGCTTTA
GGTGTAAATGCGGAAGAGTTAAAATGTGAAGTGGGAACCTATGGGTTACCAGAGTTTGGTACAAAATTTGTTAGACAAAT
GCTTGTAGATACACAACCTAATAGTTTTTCAGATTTAGTTAGAATATCAGGTCTATCCCATGGTACTGATGTATGGTTAA
ATAATGCTCAATACTATATAAAGGAAGGGTATACCACTCTTAAGGATTGTATAGCCACAAGAGATGATATAATGACTTAT
TTAATACAAAAAGATCTTCCTCCAAAAATTGCTTTTACTATAATGGAAAAAGTAAGAAAAGGGAAAGGTCTCACAGAAGA
ACATGAAGCTATAATGAGAGAACATGATGTACCTGGTTGGTATATAGAATCCTGTAAGAAAATAAAATACATGTTCCCAA
AGGGGCATGCTGTGGCTTATGTTATGATGGCAGTGAGAATAGCATATTTTAAAGTTTATTATCCTACAGCTTACTATGCT
ACCTATTTTTCAGTAAGAGCTTCTGACTTTGATGCAGAAACTGTATTTAAAGGAGAAGAAGCTATATTAAATAAAATAGA
TGAAATAAACTCTTTAGGAAACAATGTTACACAAAAAGACAAAGGACTACTTACAGTATTAGAAATATGTCATGAAATGA
ATTTAAGGGGAATAAAATTTTTAAAAGCTGATCTTTATAAATCTAATGCTTCAAAATTCTTAATAGAGGAAGAAGGCATA
AGAATACCTTTAAGTGCTATACAGGGTGTTGGAGAAAATGCAGCTAAAAATATAGTTGAGGCTCGAGAAGAAGGAGAATT
TATATCCAAAGAAGATTTAAATAAGAGAGGAAAAGCTACAAAAACTGTAATAGAAAATTTAGAAAATCATGGTTGCTTAA
GGGGACTTCCTGAATCTAATCAATTATCTTTATTTAACTTATAA

Upstream 100 bases:

>100_bases
AAAAAGGGAGAAGTAGTAAGAAAGCTTAAAGAGGAAGATTTAGTAGAAGGGCTTATAGAAGAAATAAAAAATATATAGGA
TGTGAAGGGTATGAGTTGGT

Downstream 100 bases:

>100_bases
TCCATATAAATCTTTTCCTTGAATTATATTATTTATTATGTTAAAATTAAATTTGAAAGAACTCTTAATAATTTTAGCGC
AAAAGTGGGTTTCTACCCGC

Product: DNA polymerase III PolC

Products: NA

Alternate protein names: PolIII

Number of amino acids: Translated: 1427; Mature: 1427

Protein sequence:

>1427_residues
MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKFQYFKEIEVLSYRDVSGINLK
DICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKLQYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDK
SNGKCNYLDFKEEQEALIIKNIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVF
KTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSYAREIVIMARDIVKLNKIEKM
DIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAVAITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPI
AINAGHRTLEDSYVVFDIETTGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEE
VLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKLNVVAKHLGIPLLNHHRAVED
AKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSPTYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLI
NKYREGLMIGSACEAGQVYKEVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNM
PVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKAVVTNTVKIADSIDNIKPIPD
ETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEKELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSS
LVATMTDITEVNGLPPHYVCPGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFS
GEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLGCSGVKRTTGQHPGGIMVVPQ
DNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKAL
GVNAEELKCEVGTYGLPEFGTKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTY
LIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAYVMMAVRIAYFKVYYPTAYYA
TYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKDKGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGI
RIPLSAIQGVGENAAKNIVEAREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL

Sequences:

>Translated_1427_residues
MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKFQYFKEIEVLSYRDVSGINLK
DICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKLQYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDK
SNGKCNYLDFKEEQEALIIKNIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVF
KTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSYAREIVIMARDIVKLNKIEKM
DIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAVAITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPI
AINAGHRTLEDSYVVFDIETTGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEE
VLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKLNVVAKHLGIPLLNHHRAVED
AKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSPTYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLI
NKYREGLMIGSACEAGQVYKEVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNM
PVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKAVVTNTVKIADSIDNIKPIPD
ETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEKELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSS
LVATMTDITEVNGLPPHYVCPGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFS
GEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLGCSGVKRTTGQHPGGIMVVPQ
DNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKAL
GVNAEELKCEVGTYGLPEFGTKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTY
LIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAYVMMAVRIAYFKVYYPTAYYA
TYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKDKGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGI
RIPLSAIQGVGENAAKNIVEAREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL
>Mature_1427_residues
MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKFQYFKEIEVLSYRDVSGINLK
DICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKLQYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDK
SNGKCNYLDFKEEQEALIIKNIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVF
KTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSYAREIVIMARDIVKLNKIEKM
DIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAVAITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPI
AINAGHRTLEDSYVVFDIETTGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEE
VLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKLNVVAKHLGIPLLNHHRAVED
AKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSPTYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLI
NKYREGLMIGSACEAGQVYKEVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNM
PVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKAVVTNTVKIADSIDNIKPIPD
ETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEKELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSS
LVATMTDITEVNGLPPHYVCPGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFS
GEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLGCSGVKRTTGQHPGGIMVVPQ
DNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKAL
GVNAEELKCEVGTYGLPEFGTKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTY
LIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAYVMMAVRIAYFKVYYPTAYYA
TYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKDKGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGI
RIPLSAIQGVGENAAKNIVEAREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Escherichia coli, GI1786381, Length=917, Percent_Identity=23.2279171210469, Blast_Score=121, Evalue=3e-28,
Organism=Escherichia coli, GI1786409, Length=99, Percent_Identity=34.3434343434343, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO3_CLOTE (Q895K2)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781901.1
- ProteinModelPortal:   Q895K2
- GeneID:   1059360
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01271
- NMPDR:   fig|212717.1.peg.1123
- HOGENOM:   HBG617116
- OMA:   WKTTHFD
- PhylomeDB:   Q895K2
- ProtClustDB:   PRK00448
- BioCyc:   CTET212717:CTC_01271-MONOMER
- BRENDA:   2.7.7.7
- GO:   GO:0005737
- HAMAP:   MF_00356
- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00479
- SMART:   SM00481
- TIGRFAMs:   TIGR00573
- TIGRFAMs:   TIGR01405

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB; SSF53098 RNaseH_fold

EC number: =2.7.7.7

Molecular weight: Translated: 162362; Mature: 162362

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKF
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHCCCCHHHHHHHHHHHHH
QYFKEIEVLSYRDVSGINLKDICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKL
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDKSNGKCNYLDFKEEQEALIIK
EECCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCEEECCCCCCHHHHHHH
NIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVF
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
KTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSY
HHHHEEECCCCEEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECEECCCHH
AREIVIMARDIVKLNKIEKMDIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHCCCCEE
AITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPIAINAGHRTLEDSYVVFDIET
EEECCCHHHHCHHHHHHHHHCCEEEEEECCCEEEECCEEEEEECCCCCCCCCEEEEEEEE
TGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEE
CCCCCCCCCEEEEEEEEEECCCEEHHHHHHCCHHHHCHHHHHHHCCCHHHHHCCCCHHHH
VLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKL
HHHHHHHHHCCCEEEEECCCCCHHHHHHCHHHCCEECCCCCHHHHHHHHHHHHHHHHHHH
NVVAKHLGIPLLNHHRAVEDAKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
TYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLINKYREGLMIGSACEAGQVYK
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCCCHHHHHHH
EVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNM
HHHHCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
PVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKA
CEEEEECEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHCHHHHHHH
VVTNTVKIADSIDNIKPIPDETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEK
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSSLVATMTDITEVNGLPPHYVC
HHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
PGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFS
CCCCCCCEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCCCEEECCC
GEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLG
CCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEC
CSGVKRTTGQHPGGIMVVPQDNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDI
CCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEE
LGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKALGVNAEELKCEVGTYGLPEFG
ECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHEEECCCCCCCHHH
TKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTY
HHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHH
LIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAY
HHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEECCCCHHHHH
VMMAVRIAYFKVYYPTAYYATYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKD
HHHHHHHHHHHEECCHHEEHHEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHH
KGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGIRIPLSAIQGVGENAAKNIVE
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHCCCCCHHHHHHHH
AREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL
HHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKF
CCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHCCCCHHHHHHHHHHHHH
QYFKEIEVLSYRDVSGINLKDICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKL
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDKSNGKCNYLDFKEEQEALIIK
EECCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCEEECCCCCCHHHHHHH
NIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVF
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
KTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSY
HHHHEEECCCCEEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECEECCCHH
AREIVIMARDIVKLNKIEKMDIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHCCCCEE
AITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPIAINAGHRTLEDSYVVFDIET
EEECCCHHHHCHHHHHHHHHCCEEEEEECCCEEEECCEEEEEECCCCCCCCCEEEEEEEE
TGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEE
CCCCCCCCCEEEEEEEEEECCCEEHHHHHHCCHHHHCHHHHHHHCCCHHHHHCCCCHHHH
VLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKL
HHHHHHHHHCCCEEEEECCCCCHHHHHHCHHHCCEECCCCCHHHHHHHHHHHHHHHHHHH
NVVAKHLGIPLLNHHRAVEDAKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
TYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLINKYREGLMIGSACEAGQVYK
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCCCHHHHHHH
EVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNM
HHHHCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
PVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKA
CEEEEECEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHCHHHHHHH
VVTNTVKIADSIDNIKPIPDETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEK
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSSLVATMTDITEVNGLPPHYVC
HHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
PGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFS
CCCCCCCEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCCCEEECCC
GEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLG
CCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEC
CSGVKRTTGQHPGGIMVVPQDNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDI
CCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEE
LGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKALGVNAEELKCEVGTYGLPEFG
ECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHEEECCCCCCCHHH
TKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTY
HHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHH
LIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAY
HHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEECCCCHHHHH
VMMAVRIAYFKVYYPTAYYATYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKD
HHHHHHHHHHHEECCHHEEHHEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHH
KGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGIRIPLSAIQGVGENAAKNIVE
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEHHHHCCCCCHHHHHHHH
AREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL
HHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129