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The map label for this gene is tsf

Identifier: 28210948

GI number: 28210948

Start: 1351985

End: 1352899

Strand: Direct

Name: tsf

Synonym: CTC01262

Alternate gene names: 28210948

Gene position: 1351985-1352899 (Clockwise)

Preceding gene: 28210947

Following gene: 28210949

Centisome position: 48.3

GC content: 31.48

Gene sequence:

>915_bases
ATGATAACTGCTAAAATGGTAAAAGAACTTAGAGAAATAACTGGTGCAGGTATGATGGATTGTAAAAAAGCTTTAACAGA
AACTAATGGAGATACTGAAAAAGCTGTAGAAGTATTAAGAGAAAAAGGATTAGCTGCTGCGGCTAAAAAATCAGGAAGAA
TAGCAGCAGAAGGACTTGTAGAAACTTATATAGCTGAAGATAAAAAGAATGCTTCAATAGTAGAAGTAAACTGTGAAACA
GATTTCGTAGCAGCAAATGAAGAGTTTAAAGGACTTGTTGCTAATATAGCAAAACAAGCTGCAAATACAAAGGCTGAAGA
TGTTGATTCTTTTATAGAAGAAAAATACATAGGAAGCGAAGAAGGTACAATTAAAGATGCAGTTACTGCATTAGTTGCAA
AGCTTGGAGAAAATATGTCTGTAAGAAGATTTAAACAATTATCTGTTGAAAATGGAATAATTGAAAGTTATATACACGGA
GATGGAAAAATAGGTGTATTAGTAGAATTAGAATGTGAAAAAGAAAGCGAAGTATTAAGTGAAGTAGCGAAAGATGTAGC
AATGCAAGTAGCTGCAGTTAATCCTCCTTTCTTAGATAGAACATTTGTAGATGAAGAAACTTTAGACAAAGAAAGAGAAA
TCTACAGAGTTCAAGCTTTAAATGAAGGAAAACCTGAAAAAATTGTTGATAAAATGGTAGAAGGAAGAATTCAAAAATAC
TACAAAGAAAACTGCCTAGTTGAGCAAGTTTGGGTTAGAAATTCAGATTACACTATAGATAAATACGTTAAAGAAAAATC
TAAAGAAGTTGGAGCAGATATAAAAGTTGCTAATTTTGTTAGATTTGAAAAAGGTGAAGGCATAGAAAAGAAAGAAGAAG
ATTTTGCAGAAGAAGTTAAGAAGCAAATGCAATAA

Upstream 100 bases:

>100_bases
CAATTAGCTGAGTAATCCAAAAAAACATTTTAAAAAAGGTAGATGATATTAATTCATTTACCTTTTAAAAAAAGAATTAA
TAACACAGGAGGTCATAAGT

Downstream 100 bases:

>100_bases
TTAAAGAGAGAACACTGAGTGTTCTCTTTTTTTGAGAAAATCACAGAAAACATCAATTGATACATCTATAACCAAAAATG
CTTTTTGAAATAAAAGTTCT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MITAKMVKELREITGAGMMDCKKALTETNGDTEKAVEVLREKGLAAAAKKSGRIAAEGLVETYIAEDKKNASIVEVNCET
DFVAANEEFKGLVANIAKQAANTKAEDVDSFIEEKYIGSEEGTIKDAVTALVAKLGENMSVRRFKQLSVENGIIESYIHG
DGKIGVLVELECEKESEVLSEVAKDVAMQVAAVNPPFLDRTFVDEETLDKEREIYRVQALNEGKPEKIVDKMVEGRIQKY
YKENCLVEQVWVRNSDYTIDKYVKEKSKEVGADIKVANFVRFEKGEGIEKKEEDFAEEVKKQMQ

Sequences:

>Translated_304_residues
MITAKMVKELREITGAGMMDCKKALTETNGDTEKAVEVLREKGLAAAAKKSGRIAAEGLVETYIAEDKKNASIVEVNCET
DFVAANEEFKGLVANIAKQAANTKAEDVDSFIEEKYIGSEEGTIKDAVTALVAKLGENMSVRRFKQLSVENGIIESYIHG
DGKIGVLVELECEKESEVLSEVAKDVAMQVAAVNPPFLDRTFVDEETLDKEREIYRVQALNEGKPEKIVDKMVEGRIQKY
YKENCLVEQVWVRNSDYTIDKYVKEKSKEVGADIKVANFVRFEKGEGIEKKEEDFAEEVKKQMQ
>Mature_304_residues
MITAKMVKELREITGAGMMDCKKALTETNGDTEKAVEVLREKGLAAAAKKSGRIAAEGLVETYIAEDKKNASIVEVNCET
DFVAANEEFKGLVANIAKQAANTKAEDVDSFIEEKYIGSEEGTIKDAVTALVAKLGENMSVRRFKQLSVENGIIESYIHG
DGKIGVLVELECEKESEVLSEVAKDVAMQVAAVNPPFLDRTFVDEETLDKEREIYRVQALNEGKPEKIVDKMVEGRIQKY
YKENCLVEQVWVRNSDYTIDKYVKEKSKEVGADIKVANFVRFEKGEGIEKKEEDFAEEVKKQMQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=220, Percent_Identity=30.9090909090909, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI1786366, Length=302, Percent_Identity=43.7086092715232, Blast_Score=207, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17561440, Length=301, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19921466, Length=300, Percent_Identity=28, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_CLOTE (Q895L1)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781892.1
- ProteinModelPortal:   Q895L1
- SMR:   Q895L1
- GeneID:   1059130
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01262
- NMPDR:   fig|212717.1.peg.1114
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q895L1
- ProtClustDB:   PRK09377
- BioCyc:   CTET212717:CTC_01262-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 33954; Mature: 33954

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAKMVKELREITGAGMMDCKKALTETNGDTEKAVEVLREKGLAAAAKKSGRIAAEGLV
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
ETYIAEDKKNASIVEVNCETDFVAANEEFKGLVANIAKQAANTKAEDVDSFIEEKYIGSE
HHHHHCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
EGTIKDAVTALVAKLGENMSVRRFKQLSVENGIIESYIHGDGKIGVLVELECEKESEVLS
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEECCHHHHHHH
EVAKDVAMQVAAVNPPFLDRTFVDEETLDKEREIYRVQALNEGKPEKIVDKMVEGRIQKY
HHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YKENCLVEQVWVRNSDYTIDKYVKEKSKEVGADIKVANFVRFEKGEGIEKKEEDFAEEVK
HHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHEECCCCCCCHHHHHHHHHHH
KQMQ
HHCC
>Mature Secondary Structure
MITAKMVKELREITGAGMMDCKKALTETNGDTEKAVEVLREKGLAAAAKKSGRIAAEGLV
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
ETYIAEDKKNASIVEVNCETDFVAANEEFKGLVANIAKQAANTKAEDVDSFIEEKYIGSE
HHHHHCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
EGTIKDAVTALVAKLGENMSVRRFKQLSVENGIIESYIHGDGKIGVLVELECEKESEVLS
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEEECCHHHHHHH
EVAKDVAMQVAAVNPPFLDRTFVDEETLDKEREIYRVQALNEGKPEKIVDKMVEGRIQKY
HHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YKENCLVEQVWVRNSDYTIDKYVKEKSKEVGADIKVANFVRFEKGEGIEKKEEDFAEEVK
HHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHEECCCCCCCHHHHHHHHHHH
KQMQ
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129