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The map label for this gene is fhuG [H]

Identifier: 28210885

GI number: 28210885

Start: 1279432

End: 1280439

Strand: Direct

Name: fhuG [H]

Synonym: CTC01196

Alternate gene names: 28210885

Gene position: 1279432-1280439 (Clockwise)

Preceding gene: 28210884

Following gene: 28210886

Centisome position: 45.71

GC content: 31.55

Gene sequence:

>1008_bases
ATGATTAATGATATGAAAAATATGAAAGAAATAAATAAGATAATTATTATATTACTCTCTTTTTTATTATTAATAAGTTT
AATAGTTATAACAATTGGAATGGGTAGTGTAAATTTACCGATTGGAGATATAATAGATGTTTTTTTAGGAAAAGGAAGTA
AAATAAATGAAAGTATAATAATGGACATGAGGTTACCTAGAATAATTCTTGCAGTATTTGTAGGAGCAGGACTTTCTATA
TCAGGGGCTTTATTACAATCTGTTATGAAAAACCCACTAGCAGACCCAGGAATAACAGGAGTATCTTCTGGAGGAAGCTT
AGCAGCTATTTTGATAATGCTATATTTTCCACAAATGTATAAGGCACTGCCTCTTATAGCTTTTTTAGGATCTATATTGG
CATGTACTATAGTATTCTTTTTATCTTGGGATAATGGTATAAAACCTATGAGAGTAATTTTATCTGGAGTGGCTGTGAAT
GCAATGTTTTTAGGAGCAACTTCATTATTGGCTATATTGAATACAGAAAAAATTCAAGGAGTCTTACTATGGGTAAATGG
AAGTATTGCATATAGGGGTTGGAGAGAAGTTGGTTATTTTTTACCCTATTGTATTATAGGAATTCTGTTATCATTTTTTT
GCATAAGAGGAGCTAATATATTAGCACTTGGAGATGATGTCGCTACTAATTTAGGTGTAAATGTAAATAGAACAAGAATA
TTAATATCTGTAGTGGCAGTATTTTTAGCAGGAATAAGTACGTCAGCTGTTGGGATTATAGGATTTATAGGTCTTATAGT
ACCACATATATGTAGGCTTATATTAGGATATGATTATAAGACTTTGGTCCCATTGAGTGCGATTTTGGGAGGAACAATAT
TACTTTTAGCAGATACCTTAGCACGATATATAGCAAGACCAATAGAATTACCAGTAGGGGTATTAATGTCTATGATAGGC
GGACCATTTTTCTTATTCTTACTAAGGAGGCGAAAGGACAATGCTTAA

Upstream 100 bases:

>100_bases
ATATGACTTAGATCCTAAATATTTTGGAGTTACAGGAGACATAAAACAAGTAGAGTCATTAAAAATGATGAAAGATTATT
TATATAAATAAAGTAAGGAA

Downstream 100 bases:

>100_bases
AGTGGATAATTTTAAGGTAGGTTATGATAATAAAATTATAGTAAAAGATTTTAATCTTCATGTTAAAAAGGGAGATATAA
TAACTATAATAGGTCCTAAT

Product: putative ferrichrome ABC transporter

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MINDMKNMKEINKIIIILLSFLLLISLIVITIGMGSVNLPIGDIIDVFLGKGSKINESIIMDMRLPRIILAVFVGAGLSI
SGALLQSVMKNPLADPGITGVSSGGSLAAILIMLYFPQMYKALPLIAFLGSILACTIVFFLSWDNGIKPMRVILSGVAVN
AMFLGATSLLAILNTEKIQGVLLWVNGSIAYRGWREVGYFLPYCIIGILLSFFCIRGANILALGDDVATNLGVNVNRTRI
LISVVAVFLAGISTSAVGIIGFIGLIVPHICRLILGYDYKTLVPLSAILGGTILLLADTLARYIARPIELPVGVLMSMIG
GPFFLFLLRRRKDNA

Sequences:

>Translated_335_residues
MINDMKNMKEINKIIIILLSFLLLISLIVITIGMGSVNLPIGDIIDVFLGKGSKINESIIMDMRLPRIILAVFVGAGLSI
SGALLQSVMKNPLADPGITGVSSGGSLAAILIMLYFPQMYKALPLIAFLGSILACTIVFFLSWDNGIKPMRVILSGVAVN
AMFLGATSLLAILNTEKIQGVLLWVNGSIAYRGWREVGYFLPYCIIGILLSFFCIRGANILALGDDVATNLGVNVNRTRI
LISVVAVFLAGISTSAVGIIGFIGLIVPHICRLILGYDYKTLVPLSAILGGTILLLADTLARYIARPIELPVGVLMSMIG
GPFFLFLLRRRKDNA
>Mature_335_residues
MINDMKNMKEINKIIIILLSFLLLISLIVITIGMGSVNLPIGDIIDVFLGKGSKINESIIMDMRLPRIILAVFVGAGLSI
SGALLQSVMKNPLADPGITGVSSGGSLAAILIMLYFPQMYKALPLIAFLGSILACTIVFFLSWDNGIKPMRVILSGVAVN
AMFLGATSLLAILNTEKIQGVLLWVNGSIAYRGWREVGYFLPYCIIGILLSFFCIRGANILALGDDVATNLGVNVNRTRI
LISVVAVFLAGISTSAVGIIGFIGLIVPHICRLILGYDYKTLVPLSAILGGTILLLADTLARYIARPIELPVGVLMSMIG
GPFFLFLLRRRKDNA

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=321, Percent_Identity=37.0716510903427, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1790741, Length=291, Percent_Identity=33.6769759450172, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786805, Length=302, Percent_Identity=35.0993377483444, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786804, Length=326, Percent_Identity=33.4355828220859, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1786347, Length=335, Percent_Identity=27.4626865671642, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=34.2560553633218, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36011; Mature: 36011

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDMKNMKEINKIIIILLSFLLLISLIVITIGMGSVNLPIGDIIDVFLGKGSKINESII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHH
MDMRLPRIILAVFVGAGLSISGALLQSVMKNPLADPGITGVSSGGSLAAILIMLYFPQMY
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KALPLIAFLGSILACTIVFFLSWDNGIKPMRVILSGVAVNAMFLGATSLLAILNTEKIQG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
VLLWVNGSIAYRGWREVGYFLPYCIIGILLSFFCIRGANILALGDDVATNLGVNVNRTRI
EEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCHHHH
LISVVAVFLAGISTSAVGIIGFIGLIVPHICRLILGYDYKTLVPLSAILGGTILLLADTL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ARYIARPIELPVGVLMSMIGGPFFLFLLRRRKDNA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINDMKNMKEINKIIIILLSFLLLISLIVITIGMGSVNLPIGDIIDVFLGKGSKINESII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHH
MDMRLPRIILAVFVGAGLSISGALLQSVMKNPLADPGITGVSSGGSLAAILIMLYFPQMY
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KALPLIAFLGSILACTIVFFLSWDNGIKPMRVILSGVAVNAMFLGATSLLAILNTEKIQG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
VLLWVNGSIAYRGWREVGYFLPYCIIGILLSFFCIRGANILALGDDVATNLGVNVNRTRI
EEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCHHHH
LISVVAVFLAGISTSAVGIIGFIGLIVPHICRLILGYDYKTLVPLSAILGGTILLLADTL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ARYIARPIELPVGVLMSMIGGPFFLFLLRRRKDNA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]